Zobrazeno 1 - 10
of 17
pro vyhledávání: '"T. H. Foster"'
Publikováno v:
Biomedical Optical Spectroscopy and Diagnostics.
We have constructed a steady-state radially-resolved dif€use reflectance spectrometer capable of simultaneously measuring the absorption (μa) and transport scattering (μa′) spectra of tissue-simulating phantoms within an adjustable 160 nm wavel
Publikováno v:
Photochemistry and photobiology. 73(6)
Remarkable rates of oxygen consumption are observed via microelectrode measurements immediately upon the onset of 325 nm irradiation of multicell tumor spheroids. Consumption is irradiance dependent over the range 20-200 mW cm-2, and its magnitude is
Autor:
S, Coutier, S, Mitra, L N, Bezdetnaya, R M, Parache, I, Georgakoudi, T H, Foster, F, Guillemin
Publikováno v:
Photochemistry and photobiology. 73(3)
We report the influence of fluence rate on the photobleaching and cell survival in Colo 26 multicell spheroids photosensitized by meta-tetra-(hydroxyphenyl)chlorin (mTHPC). Photosensitizer degradation and therapeutic efficacy increased dramatically a
Publikováno v:
Photochemistry and photobiology. 73(1)
Photobleaching kinetics of aminolevulinic acid-induced protoporphyrin IX (PpIX) were measured in the normal skin of rats in vivo using a technique in which fluorescence spectra were corrected for the effects of tissue optical properties in the emissi
Autor:
I, Georgakoudi, T H, Foster
Publikováno v:
Photochemistry and photobiology. 68(1)
We present experimental evidence that demonstrates directly how the subcellular localization and redistribution of two nile blue derivatives, 5-ethylamino-9-diethyl-aminobenzo[a]phenothiazinium chloride (EtNBS) and 5-ethylamino-9-diethyl-aminobenzo[a
Publikováno v:
Photochemistry and photobiology. 65(3)
Photodynamic therapy (PDT), a novel treatment for a variety of human malignancies, usually consists of visible light irradiation of lesions following the systemic administration of a photosensitizer. Induction of the endogenous photosensitizer protop
Publikováno v:
Cancer research. 55(8)
We examined the effectiveness of systemic administration of delta-aminolevulinic acid (delta-ALA) to induce endogenous protoporphyrin as a regimen for use in photodynamic therapy (PDT) of transplanted R3230AC rat mammary adenocarcinomas in vivo. Leve
Publikováno v:
Cancer research. 53(6)
EMT6/Ro spheroids approximately 500 microns in diameter were subjected to photodynamic therapy administered at various incident radiation fluence rates. Following 24 h incubation with 10 micrograms/ml Photofrin, groups of spheroids were irradiated at
Autor:
L A, Sporn, T H, Foster
Publikováno v:
Cancer research. 52(12)
Endothelial cells were cultured from human umbilical veins and incubated with Photofrin (1 microgram/ml). Cells were then exposed to light, and cytoplasmic microtubule (MT) status was monitored by immunofluorescence microscopy using alpha-tubulin ant
Publikováno v:
Cancer research. 51(12)
Cultured endothelial cells from the human umbilical vein were incubated with low concentrations (1 microgram/ml) of the photosensitizer Photofrin II. Following a sublethal light exposure, a light dose-dependent release of von Willebrand factor (vWf)