Zobrazeno 1 - 10
of 29
pro vyhledávání: '"T. H. C. Cheung"'
Autor:
Yunmin Ding, T. H. C. Cheung, Neal Joshi, David Sulzer, Un Jung Kang, Thong C. Ma, Se Joon Choi, Eugene V. Mosharov
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
SummaryChanges in striatal cholinergic interneuron (ChI) activity are thought to contribute to Parkinson’s disease pathophysiology and dyskinesia from chronic L-3,4-dihydroxyphenylalanine (L-DOPA) treatment, but the physiological basis of these cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbc5a8dcd0bbf987bc702923cfee42f
https://doi.org/10.1101/2020.02.14.950022
https://doi.org/10.1101/2020.02.14.950022
Autor:
Martin Dufwenberg, Nora R. Dado, Rachel Mendoza, Kayla N. Hatch, Allegra Campagna, Janet L. Neisewander, Hanna Molla, Natalie A. Peartree, Julianna Goenaga, Joshua S. Talboom, T. H. C. Cheung
Publikováno v:
Psychopharmacology. 234:1815-1828
Smoking typically begins during adolescence or early adulthood in a social context, yet the role of social context in animal models is poorly understood. The present study examined the effect of social context on acquisition of nicotine self-administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e743539c30dcaa713fe5bbabaea17292
https://doi.org/10.1007/s00213-017-4590-0
https://doi.org/10.1007/s00213-017-4590-0
Autor:
T. H. C. Cheung, Jozsef Meszaros, Un Jung Kang, Dalibor Sames, Christoph Kellendonk, Maya M Erler, David Sulzer
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Dopamine neurotransmission is suspected to play important physiological roles in multiple sparsely innervated brain nuclei, but there has not been a means to measure synaptic dopamine release in such regions. The globus pallidus externa (GPe) is a ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bc285e34732b7a5c5ff64a6e97dfbb
https://elifesciences.org/articles/42383
https://elifesciences.org/articles/42383
Autor:
C. M. Bradshaw, G. Bezzina, Jeffrey C. Glennon, Simon C. Body, T. H. C. Cheung, C. L. Hampson, Elemer Szabadi
Publikováno v:
Psychopharmacology, 232, 4, pp. 699-711
Psychopharmacology, 232, 699-711
Psychopharmacology, 232, 699-711
Item does not contain fulltext RATIONALE: 5-Hydroxytryptamine2C (5-HT2C) receptor agonists reduce the breakpoint in progressive ratio schedules of reinforcement, an effect that has been attributed to a decrease of the efficacy of positive reinforcers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06203f41a938ecb719d9afda0046191
https://doi.org/10.1007/s00213-014-3700-5
https://doi.org/10.1007/s00213-014-3700-5
Autor:
Robert H. Mach, Kayla N. Chandler, Robert R. Luedtke, Romina F. Schaan, Amy L. Loriaux, Suzanne M. Weber, Janet L. Neisewander, T. H. C. Cheung, Jeffrey D. Lenz
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 347:410-423
Dopamine D3 receptor (D3R)-selective compounds may be useful medications for cocaine dependence. In this study, we identified two novel arylamide phenylpiperazines, OS-3-106 and WW-III-55, as partial agonists at the D3R in the adenylyl cyclase inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60265a667ebda3a6aa1b7ee125f4f0b
https://doi.org/10.1124/jpet.112.202911
https://doi.org/10.1124/jpet.112.202911
Autor:
Robert H. Mach, Brian C. Nolan, Robert R. Luedtke, Janet L. Neisewander, Shinban Liu, T. H. C. Cheung, Jeffrey D. Lenz, Lindsey R. Hammerslag
Publikováno v:
Synapse. 67:847-855
WC 44 and WC 10 are phenylpiperazines with low (23 fold) to moderate (42 fold) selectivity for dopamine D3 receptors (D3Rs) over D2Rs, respectively. WC 44 is a full D3R agonist in the forskolin-stimulated adenylyl cyclase (AC) assay, whereas WC 10 ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::543e9c5b1ffa0bf8d31581d3b8bae169
https://doi.org/10.1002/syn.21691
https://doi.org/10.1002/syn.21691
Autor:
B. C. Nolan, T. H. C. Cheung, Janet L. Neisewander, Natalie A. Peartree, Robert T. Luedtke, J. P. Durbin, Lindsey R. Hammerslag, Robert H. Mach, Suzanne M. Weber
Publikováno v:
Neuropharmacology. 63:1346-1359
This study examined cocaine self-administration after pretreatments with three structurally related compounds that bind selectively to dopamine D3 receptors (D3Rs) relative to the D2 receptor subtype (D2Rs) and exhibit varying intrinsic activities in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b87260cd02b32a5311ee945ad098395
https://doi.org/10.1016/j.neuropharm.2012.08.011
https://doi.org/10.1016/j.neuropharm.2012.08.011
Publikováno v:
Behavioural Processes. 90:111-123
Extinction performance is often used to assess underlying psychological processes without the interference of reinforcement. For example, in the extinction/reinstatement paradigm, motivation to seek drug is assessed by measuring responding elicited b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4103936729f135e8aadb97e3559fd5
https://doi.org/10.1016/j.beproc.2012.02.012
https://doi.org/10.1016/j.beproc.2012.02.012
Autor:
C. M. Bradshaw, Simon C. Body, F.S. den Boon, G. Bezzina, T. H. C. Cheung, E. Szabadi, C. L. Hampson, Kevin C. F. Fone, R. W. Langley
Publikováno v:
Behavioural Pharmacology. 21:11-20
Rats' ability to discriminate durations is disrupted by the monoamine-releasing agent D-amphetamine and the 5-HT2 receptor agonist 2,5-dimethoxy-4-iodoamphetamine (DOI). It is unknown whether this effect is specific for temporal discrimination or ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef2a126cfe9cd8232b91b302ec06283
https://doi.org/10.1097/fbp.0b013e328334707a
https://doi.org/10.1097/fbp.0b013e328334707a