Zobrazeno 1 - 10
of 406
pro vyhledávání: '"T. Hünig"'
Publikováno v:
Clinical and Developmental Immunology, Vol 4, Iss 3, Pp 181-188 (1995)
Externí odkaz:
https://doaj.org/article/bedcfe19a19941aea069a0b568936b40
Akademický článek
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Publikováno v:
AIDS Research and Human Retroviruses. 18:1319-1325
Downregulation of MHC class I expression following human immunodeficiency virus 1 (HIV-1) infection is thought to play an important role in viral escape from immune recognition by cytotoxic T-lymphocytes (CTLs). Since exogenous addition of HIV-1-deri
Autor:
M Pallardy, T Hünig
Publikováno v:
British Journal of Pharmacology. 161:509-511
The failure of toxicity studies in non-human primates to predict the cytokine release syndrome during a first-in-man study of the CD28-specific monoclonal antibody TGN1412 has remained unexplained so far. In this issue of the BJP, work from the NIBSC
Autor:
Bernd Sido, R. Zimmerman, T. Hünig, Christian F. Vahl, Thomas J. Dengler, Gábor Szabó, Stefan Meuer, W. Nottmeyer
Publikováno v:
Transplantation. 67:392-398
Background. Allograft rejection depends on T cell immune responses requiring antigen recognition and costimulatory signals through accessory T cell receptors, including CD28. Inhibition of CD28 signaling with a CTLA-4-immunoglobulin (Ig) fusion prote
Publikováno v:
The Journal of Immunology. 157:4436-4441
This study addresses the molecular basis of a Tcrb-V polymorphism in the reactivity to the superantigens staphylococcus enterotoxin B (SEB) and the mtv-7 sag (MIs1a) of T cells recognized by the mAb R78, which reacts with the T cell receptor beta-cha
Publikováno v:
International Immunology. 8:1221-1227
DBA/1 (H-2q) and C57BL/6 (H-2b) mice develop an intermediate immune responses when immunized with chicken type II collagen (CII) emulsified with incomplete Freund's adjuvant (IFA). Only a few animals develop a mild form of arthritis. As reported befo
Publikováno v:
The Journal of Immunology. 154:5121-5127
CD28 has been identified in man and mouse as a potent costimulatory receptor on T cells. We have generated a mAb, called JJ319, to rat CD28 and show that it is expressed on virtually all peripheral rat alpha beta and on most gamma delta T cells, and
Publikováno v:
The Journal of Immunology. 154:4390-4394
The biologic role and repertoire of cells bearing the gamma delta T cell receptor has not been fully defined. However, their tropism for epithelial microenvironments is recognized and suggests an important role for these cells in immune defense at mu
Publikováno v:
The Journal of Immunology. 153:979-986
A mAb called V65 was raised to a CD3+, TCR-alpha/beta- rat/mouse T cell hybrid that selectively reacts with all CD3+, TCR-alpha/beta- rat lymphocytes. Both anti-CD3 and V65 precipitate a 48- to 50-kDa heterodimeric protein from digitonin-lysed surfac