Zobrazeno 1 - 10
of 301
pro vyhledávání: '"T. Grey"'
Autor:
Jared M. Campbell, Saabah B. Mahbub, Ayad G. Anwer, Abbas Habibalahi, Stan Gronthos, Sharon Paton, Shane T. Grey, Lindsay E. Wu, Robert B. Gilchrist, Ewa M. Goldys
Publikováno v:
Cells, Vol 13, Iss 20, p 1731 (2024)
Understanding the molecular mechanisms of differentiation is important for regenerative medicine and developmental biology. This study aims to characterise the role of the glycolysis/oxidative phosphorylation balance as a driver of mesenchymal stem c
Externí odkaz:
https://doaj.org/article/6fc592edb3774f5e8a345c5ad1d27934
Autor:
Abbas Habibalahi, Jared M. Campbell, Stacey N. Walters, Saabah B. Mahbub, Ayad G. Anwer, Shane T. Grey, Ewa M. Goldys
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1851-1859 (2023)
Islets transplanted for type-1 diabetes have their viability reduced by warm ischemia, dimethyloxalylglycine (DMOG; hypoxia model), oxidative stress and cytokine injury. This results in frequent transplant failures and the major burden of patients ha
Externí odkaz:
https://doaj.org/article/e3f1f2fe6db1478f866cff0d8c98e40f
Autor:
Kay K. Myo Min, Darling Rojas-Canales, Daniella Penko, Mark DeNichilo, Michaelia P. Cockshell, Charlie B. Ffrench, Emma J. Thompson, Olof Asplund, Christopher J. Drogemuller, Rashmi B. Prasad, Leif Groop, Shane T. Grey, Helen E. Thomas, Thomas Loudovaris, Thomas W. Kay, My G. Mahoney, Claire F. Jessup, P. Toby Coates, Claudine S. Bonder
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-15 (2022)
Abstract Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune processes and β-cell dysfunction are known to occur in type 1 diabetes, a compl
Externí odkaz:
https://doaj.org/article/afcc41530a1443548bde1470cff8d8ab
Autor:
Jared M. Campbell, Stacey N. Walters, Abbas Habibalahi, Saabah B. Mahbub, Ayad G. Anwer, Shannon Handley, Shane T. Grey, Ewa M. Goldys
Publikováno v:
Cells, Vol 12, Iss 18, p 2302 (2023)
Islets prepared for transplantation into type 1 diabetes patients are exposed to compromising intrinsic and extrinsic factors that contribute to early graft failure, necessitating repeated islet infusions for clinical insulin independence. A lack of
Externí odkaz:
https://doaj.org/article/c9315b8b587b41bd91763a294813a4cd
Autor:
Nathan W. Zammit, Joseph McDowell, Joanna Warren, Walter Muskovic, Joanne Gamble, Yan-Chuan Shi, Dominik Kaczorowski, Chia-Ling Chan, Joseph Powell, Chris Ormandy, David Brown, Samantha R. Oakes, Shane T. Grey
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Women with autoimmune and inflammatory aetiologies can exhibit reduced fecundity. TNFAIP3 is a master negative regulator of inflammation, and has been linked to many inflammatory conditions by genome wide associations studies, however its role in fer
Externí odkaz:
https://doaj.org/article/a3dbda4377db4fd2b3439ec0ab65c36f
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a95bb2d277024b8081612bbcbbcb458d
Autor:
Natasha M. Rogers, Nathan Zammit, Danny Nguyen-Ngo, Yassine Souilmi, Nikita Minhas, Daniel N. Meijles, Eleanor Self, Stacey N. Walters, Joanna Warren, Daniele Cultrone, Maryam El-Rashid, Jennifer Li, Tatyana Chtanova, Philip J. O’Connell, Shane T. Grey
Publikováno v:
Kidney International. 103:1105-1119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5349e71cf0f3e0b159c18a935683bda9
https://doi.org/10.1016/j.kint.2023.02.030
https://doi.org/10.1016/j.kint.2023.02.030
Autor:
Claire Vennin, Pauline Mélénec, Romain Rouet, Max Nobis, Aurélie S. Cazet, Kendelle J. Murphy, David Herrmann, Daniel A. Reed, Morghan C. Lucas, Sean C. Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T. Grey, Andrew Da Silva, Wilfred Leung, Australian Pancreatic Genome Initiative (APGI), Suresh Mathivanan, Yingxiao Wang, Anthony W. Braithwaite, Daniel Christ, Ales Benda, Ashleigh Parkin, Phoebe A. Phillips, John M. Whitelock, Anthony J. Gill, Owen J. Sansom, David R. Croucher, Benjamin L. Parker, Marina Pajic, Jennifer P. Morton, Thomas R. Cox, Paul Timpson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-22 (2019)
Subtypes of cancer associated fibroblasts can both promote and suppress tumorigenesis. Here, the authors investigate how p53 status in pancreatic cancer cells affects their interaction with cancer associated fibroblasts, and report perlecan as a medi
Externí odkaz:
https://doaj.org/article/9cbe7f002204495db0cd437d4360e24c
Autor:
Darling Rojas-Canales, Stacey N. Walters, Daniella Penko, Daniele Cultrone, Jacqueline Bailey, Tatyana Chtanova, Jodie Nitschke, Julie Johnston, Svjetlana Kireta, Thomas Loudovaris, Thomas W. Kay, Tim R. Kuchel, Wayne Hawthorne, Philip J. O’Connell, Greg Korbutt, John E. Greenwood, Shane T. Grey, Chris J. Drogemuller, P. Toby Coates
Publikováno v:
Diabetes. 72:758-768
Intrahepatic islet transplantation for type 1 diabetes is limited by the need for multiple infusions and poor islet viability posttransplantation. The development of alternative transplantation sites is necessary to improve islet survival and facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5805a900a3f68cf12f75bc32ef3662c
https://doi.org/10.2337/db21-0841
https://doi.org/10.2337/db21-0841
Autor:
Andrew O. Yam, Jacqueline Bailey, Francis Lin, Arnolda Jakovija, Scott E. Youlten, Claudio Counoupas, Matthias Gunzer, Tobias Bald, Trent M. Woodruff, James A. Triccas, Leonard D. Goldstein, David Gallego-Ortega, Shane T. Grey, Tatyana Chtanova
Publikováno v:
Cancer Research. 83:1315-1328
The inflammatory microenvironment of solid tumors creates a protumorigenic milieu that resembles chronic inflammation akin to a subverted wound healing response. Here, we investigated the effect of converting the tumor microenvironment from a chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec6dded98834e150ef95012c32f4cc1
https://doi.org/10.1158/0008-5472.can-21-4025
https://doi.org/10.1158/0008-5472.can-21-4025