Zobrazeno 1 - 10
of 3 326
pro vyhledávání: '"T. Graham"'
Publikováno v:
Gynecologic Oncology Reports, Vol 30, Iss , Pp - (2019)
Background: Immune checkpoint inhibitors (ICI) eliminate cancer cells through release of inhibition of cytotoxic CD8+ lymphocytes. Potent systemic activation of immune cells provides unprecedented efficacy in some types of advanced cancer therapy, bu
Externí odkaz:
https://doaj.org/article/48d4c579ab8d4a29a6c3688daea666b4
Autor:
K. D. Williams, D. Copsey, E. W. Blockley, A. Bodas‐Salcedo, D. Calvert, R. Comer, P. Davis, T. Graham, H. T. Hewitt, R. Hill, P. Hyder, S. Ineson, T. C. Johns, A. B. Keen, R. W. Lee, A. Megann, S. F. Milton, J. G. L. Rae, M. J. Roberts, A. A. Scaife, R. Schiemann, D. Storkey, L. Thorpe, I. G. Watterson, D. N. Walters, A. West, R. A. Wood, T. Woollings, P. K. Xavier
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 10, Iss 2, Pp 357-380 (2018)
Abstract The Global Coupled 3 (GC3) configuration of the Met Office Unified Model is presented. Among other applications, GC3 is the basis of the United Kingdom's submission to the Coupled Model Intercomparison Project 6 (CMIP6). This paper documents
Externí odkaz:
https://doaj.org/article/53976442308d43aebb777b949532840b
Autor:
H. T. Hewitt, M. J. Roberts, P. Hyder, T. Graham, J. Rae, S. E. Belcher, R. Bourdallé-Badie, D. Copsey, A. Coward, C. Guiavarch, C. Harris, R. Hill, J. J.-M. Hirschi, G. Madec, M. S. Mizielinski, E. Neininger, A. L. New, J.-C. Rioual, B. Sinha, D. Storkey, A. Shelly, L. Thorpe, R. A. Wood
Publikováno v:
Geoscientific Model Development, Vol 9, Iss 10, Pp 3655-3670 (2016)
There is mounting evidence that resolving mesoscale eddies and western boundary currents as well as topographically controlled flows can play an important role in air–sea interaction associated with vertical and lateral transports of heat and salt.
Externí odkaz:
https://doaj.org/article/73d03f385b474b6c97df9d955835c3bf
Autor:
M. Zhao, T. B. Wild, N. T. Graham, S. H. Kim, M. Binsted, A. F. M. K. Chowdhury, S. Msangi, P. L. Patel, C. R. Vernon, H. Niazi, H.-Y. Li, G. W. Abeshu
Publikováno v:
Geoscientific Model Development, Vol 17, Pp 5587-5617 (2024)
Reservoirs play a significant role in modifying the spatiotemporal availability of surface water to meet multi-sector human demands, despite representing a relatively small fraction of the global water budget. Yet the integrated modeling frameworks t
Externí odkaz:
https://doaj.org/article/d62e85bcc63e4a85aad35634b11354ba
Autor:
K. D. Williams, C. M. Harris, A. Bodas-Salcedo, J. Camp, R. E. Comer, D. Copsey, D. Fereday, T. Graham, R. Hill, T. Hinton, P. Hyder, S. Ineson, G. Masato, S. F. Milton, M. J. Roberts, D. P. Rowell, C. Sanchez, A. Shelly, B. Sinha, D. N. Walters, A. West, T. Woollings, P. K. Xavier
Publikováno v:
Geoscientific Model Development, Vol 8, Iss 5, Pp 1509-1524 (2015)
The latest coupled configuration of the Met Office Unified Model (Global Coupled configuration 2, GC2) is presented. This paper documents the model components which make up the configuration (although the scientific description of these components
Externí odkaz:
https://doaj.org/article/93166d9105d543d199e90711d63a474f
Autor:
A. Megann, D. Storkey, Y. Aksenov, S. Alderson, D. Calvert, T. Graham, P. Hyder, J. Siddorn, B. Sinha
Publikováno v:
Geoscientific Model Development, Vol 7, Iss 3, Pp 1069-1092 (2014)
We describe a new Global Ocean standard configuration (GO5.0) at eddy-permitting resolution, developed jointly between the National Oceanography Centre and the Met Office as part of the Joint Ocean Modelling Programme (JOMP), a working group of the U
Externí odkaz:
https://doaj.org/article/e731a061b6e3432bbb82658e4830c335
Autor:
Ginevra Lilli, Charlotte Sirot, Hayley Campbell, Fanny Hermand, Deirdre Brophy, Jean-François Flot, Conor T. Graham, Isabelle F. George
Publikováno v:
Animal Microbiome, Vol 6, Iss 1, Pp 1-24 (2024)
Abstract Background Biogeography has been linked to differences in gut microbiota in several animals. However, the existence of such a relationship in fish is not clear yet. So far, it seems to depend on the fish species studied. However, most studie
Externí odkaz:
https://doaj.org/article/99e549dc1b8940ceb123d604aae91a2c
Autor:
Enrico Pracucci, Robert T. Graham, Laura Alberio, Gabriele Nardi, Olga Cozzolino, Vinoshene Pillai, Giacomo Pasquini, Luciano Saieva, Darren Walsh, Silvia Landi, Jinwei Zhang, Andrew J. Trevelyan, Gian-Michele Ratto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Cortical activity patterns are strongly modulated by fast synaptic inhibition mediated through ionotropic, chloride-conducting receptors. Consequently, chloride homeostasis is ideally placed to regulate activity. We therefore investigated th
Externí odkaz:
https://doaj.org/article/57f6e1bbcdb94d1f836d57eeffbd978a
Autor:
Ginevra Lilli, Charlotte Sirot, Hayley Campbell, Fanny Hermand, Deirdre Brophy, Jean‑François Flot, Conor T. Graham, Isabelle F. George
Publikováno v:
Animal Microbiome, Vol 6, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/958a9b1155cd4b20a2e7acfb0548428e
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-16 (2023)
Abstract Water usage is closely linked with societal goals that are both local and global in scale, such as sustainable development and economic growth. It is therefore of value, particularly for long-term planning, to understand how future sectoral
Externí odkaz:
https://doaj.org/article/fcebdef2604e4eca970b73aba750e9f7