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of 111
pro vyhledávání: '"T. Godard"'
Autor:
Delphine Loussouarn, Mario Campone, Jérôme Abadie, F. Nguyen, Laetitia Jaillardon, T. Godard, Brigitte Siliart
Publikováno v:
Cancer Research. 73:P2-05
Background: Dogs spontaneously develop invasive mammary carcinoma with a high prevalence of the triple-negative subtype, making this model relevant for the investigation of new therapeutic pathways. Insulin-like growth factor-1 receptor (IGF-1R) is e
Akademický článek
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Publikováno v:
Immuno-analyse & Biologie Spécialisée. 24:281-288
Summary We evaluated the impact of identification in 2 h directly on positive blood cultures bottles of Staphylococcus aureus associated with mecA gene detection by GeneOhm StaphSR ® test (GOSSR) on the delay of optimal treatment and on the isolatio
Publikováno v:
Scopus-Elsevier
Iodine could be added to the diet of human population in the form of iodide or iodate but iodate had not been adequately tested for genotoxicity and carcinogenicity. In the present study, genotoxic effects of potassium iodate were evaluated in vitro
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 520:207-211
Using a particular model of apoptosis, we here demonstrate the ability of the comet assay to differentiate between different cell populations. In our study, the natural killer Kurloff cells, used as effector cells, recognize and bind to the tumoral L
Autor:
C. Vigreux, Vladimir N. Anisimov, Mark A. Zabezhinski, Véronique André, T. Godard, François Sichel, Irina G. Popovich, Elena A Zaripova, Sergey A Musatov
Publikováno v:
Cancer Letters. 156:199-205
Forty female CBA mice aged 3–4 months were exposed twice a week during 2 months to intravaginal applications of polyurethane sponges impregnated with 0.1% solution of 7,12-dimethylbenz[ a ]anthracene (DMBA) in triethyleneglycol. Three hours after e
Publikováno v:
Journal of Applied Toxicology. 19:421-430
The genotoxic potential of the fungicide malachite green (MG) and its reduced derivative leucomalachite green (LMG) was assessed in bacteria and mammalian cells using the standard Salmonella typhimurium/Ames and CHO/HGPRT tests. In vitro potential DN
Autor:
T. Godard, Edwige Deslandes, Jean-Michel Poul, François Sichel, Pascal Gauduchon, C. Vigreux, Pierre Lebailly
Publikováno v:
Histochemistry and Cell Biology. 112:155-161
Comet, TUNEL, and annexin V assays were used to identify DNA fragmentation and plasma membrane alterations occurring during staurosporine-induced apoptosis in Chinese hamster ovary cells. TUNEL assay detected apoptotic cells after 6 h treatment. The
Publikováno v:
Cell Biology and Toxicology. 15:185-192
Dysregulation of apoptosis contributes to various diseases such as neurodegenerative or aging disorders, autoimmune syndromes or cancers. Numerous experimental paradigms have been explored to characterize molecular and cellular modulators of apoptosi
Autor:
Véronique André, V.N. Anisimov, C. Vigreux, Pascal Gauduchon, S.A. Musatov, T. Godard, François Sichel
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 417:75-84
The effect of a potent endogenous antioxidant, the pineal gland indole melatonin (MLT) on the mutagenicity of twelve well-known mutagens and carcinogens has been investigated using two in vitro tests the Ames test and the single cell gel electrophore