Zobrazeno 1 - 10
of 55
pro vyhledávání: '"T. Georgouli"'
Publikováno v:
Expert Opinion on Drug Safety. 13:1525-1534
Bone morphogenetic proteins are multi-functional growth factors, which play an important role in embryonic development and cellular functions. Among several molecules in this family, BMP-2 and BMP-7 are currently being used in the clinical setting. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab370373621a4799c214576a421d89b
https://doi.org/10.1517/14740338.2014.968124
https://doi.org/10.1517/14740338.2014.968124
Publikováno v:
Injury. 44:1725-1732
Delayed bone healing and non-union occurs in approximately 10-15% of long bone fractures. Both pathologies may result in prolonged period of pain, disability and repetitive operative interventions. Despite intense investigations and progress done in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed6a66f988d2321e6763ab55873efe0
https://doi.org/10.1016/j.injury.2013.09.009
https://doi.org/10.1016/j.injury.2013.09.009
Publikováno v:
Acta Orthopaedica
Background and purpose The systemic response after fracture is regulated by a complex mechanism involving numerous growth factors. In this study, we analyzed the kinetics of key growth factors following lower-limb long bone fracture. Materials and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2759c6699e1e6234ef5bee81c1f89da
https://doi.org/10.3109/17453674.2013.765624
https://doi.org/10.3109/17453674.2013.765624
Publikováno v:
Expert Opinion on Drug Safety. 10:935-945
Bone healing is a complex cascade of events that involves the proliferation and differentiation of osteoblastic cells under the influence of signals from growth factors, cytokines and mechanical loading. Several medications have been found to interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c5e6ed41918b916ad8e7d4ecdac794
https://doi.org/10.1517/14740338.2011.589833
https://doi.org/10.1517/14740338.2011.589833
Publikováno v:
Injury : International Journal of the Care of the Injured, 39, 4, pp. 384-94
Injury : International Journal of the Care of the Injured, 39, 384-94
Injury : International Journal of the Care of the Injured, 39, 384-94
Contains fulltext : 71494.pdf (Publisher’s version ) (Closed access) Bone healing is an extremely complex process which depends on the coordinated action of several cell lineages on a cascade of biological events, and has always been a major medica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0b2fa7734adb6ac315f176fd88e6ff
https://doi.org/10.1016/j.injury.2007.10.035
https://doi.org/10.1016/j.injury.2007.10.035
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 60(4)
The aim of this study was to investigate the effect of antibiotics used in clinical practice on Mesenchymal Stem Cells (MSCs) potential to proliferate and differentiate towards an osteogenic lineage. Trabecular bone was obtained from 10 patients (mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::846e202fb2a4183b6d8886b42b72de32
https://pubmed.ncbi.nlm.nih.gov/25350512
https://pubmed.ncbi.nlm.nih.gov/25350512
Publikováno v:
Injury Extra. 43(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b87f31696e258545540246c9b54aeb
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
The Scientific World Journal
The Scientific World Journal
Nonsteroidal anti-inflammatory drugs (NSAIDs) play an essential part in our approach to control pain in the posttraumatic setting. Over the last decades, several studies suggested that NSAIDs interfere with bone healing while others contradict these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6756a2e08c32c857b65f375fbacb0d6c
https://doaj.org/article/29ef1a0ef36e40e790101368e725bbc9
https://doaj.org/article/29ef1a0ef36e40e790101368e725bbc9
Autor:
Howard A. Bird, T. Georgouli, Elena Jones, Ippokratis Pountos, K Henshaw, Peter V. Giannoudis
Publikováno v:
Journal of orthopaedic trauma. 24(9)
Introduction: It has been previously shown that in patients with osteoporosis, mesenchymal stem cell (MSC) growth rate and osteogenic potential is decreased contributing to inferior fracture consolidation. The aim of this study was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a765fe2d82f9bdec5f33a459b2ff306
https://pubmed.ncbi.nlm.nih.gov/20736793
https://pubmed.ncbi.nlm.nih.gov/20736793