Zobrazeno 1 - 10
of 19
pro vyhledávání: '"T. G. Gor'kova"'
Autor:
A. M. Scherbakov, T. I. Fetisov, D. V. Sorokin, V. Yu. Zinovieva, N. I. Moiseeva, L. A. Laletina, E. M. Kirilin, A. E. Manikaylo, L. Ya. Fomina, L. V. Mekheda, B. Yu. Bokhyan, E. A. Lesovaya, L. S. Trukhanova, T. G. Gor’kova, E. E. Antoshina, O. V. Morozova, K. I. Kirsanov, M. G. Yakubovskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 2, Pp 58-65 (2022)
Introduction. The identification of predictive factors is a cornerstone task of modern oncology. The development of new targeted drugs determines the need for prediction of chemosensitivity of each patient to the prescribed therapy, in this regard, t
Externí odkaz:
https://doaj.org/article/71afdbbddba344529bf70f023fe79b06
Autor:
T. I. Fetisov, L. R. Tilova, E. A. Lesovaya, E. E. Antoshina, T. G. Gor’kova, L. S. Trukhanova, O. V. Morozova, E. V. Shipaeva, R. V. Ivanov, A. A. Purmal, G. A. Belitskiy, M. G. Yakubovskaya, A. V. Gudkov, K. V. Gurova, K. I. Kirsanov
Publikováno v:
Успехи молекулярной онкологии, Vol 3, Iss 3, Pp 67-72 (2016)
Curaxins represent low molecular weight carbazole derivatives, which simultaneously activate p53-dependent apoptosis and inhibit NF-kBdependent signal transduction pathways. Antitumor activity of curaxin CBL0137 was demonstrated in vivo on the model
Externí odkaz:
https://doaj.org/article/e6c530241b8c4a55a5f7c6a083abc4f0
Autor:
Marianna G. Yakubovskaya, Daria Fleyshman, O. S. Morozova, Roman Ivanov, Elena V. Shipaeva, T. I. Fetisov, Andrei Purmal, Andrey Leonov, Andrei V. Gudkov, E E Antoshina, Ramiz M. Salimov, Varvara Maksimova, Ekaterina A. Lesovaya, Alfiya Safina, Gennady A. Belitsky, Katerina Gurova, L S Trukhanova, T G Gor'kova, Kirill I. Kirsanov
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 13(1)
Chemoprevention is considered a valid approach to reduce the incidence of colorectal cancer, one of the most common malignancies worldwide. Here, we investigated the tumor-preventive activity of curaxin CBL0137. This compound represents a new class o
Autor:
L S Trukhanova, Gennady A. Belitsky, Andrey V. Shubin, Kirill I. Kirsanov, Marianna G. Yakubovskaya, T G Gor'kova, E E Antoshina, Ekaterina A. Lesovaya, Ilya V. Demidyuk
Publikováno v:
Bulletin of experimental biology and medicine. 164(5)
Studies of the molecular mechanisms of esophageal cancer development have to be carried out on sufficient amount of tumor material, obtained under conditions of controlled exposure to carcinogenic factors. Esophageal cancer models on laboratory anima
Autor:
E E Antoshina, Gennady A. Belitsky, Mikhail V. Blagosklonny, L S Trukhanova, Elena V. Shipaeva, Ramiz M. Salimov, Marianna G. Yakubovskaya, Olga B. Chernova, T G Gor'kova, Ekaterina A. Lesovaya, Kirill I. Kirsanov
Publikováno v:
Oncotarget
Benign prostatic hyperplasia (BPH) is the most common age-related disease in men. Here we tested the efficacy of Rapatar, a micellar nanoformulation of rapamycin, in two rat models of BPH: testosterone-induced and sulpiride-induced hyperplasia in ven
Autor:
V A, Kobliakov, E E, Antoshina, T G, Gor'kova, I L, Gol'dman, L S, Trukhanova, E R, Sadchikova
Publikováno v:
Voprosy onkologii. 58(5)
There was studied effect of recombinant form of human breast milk component-lactoferrin, received from milk of goats-producers (neolactoferrin), on growth of transplantable tumor of the cervix in mice (TTC-5). Neolactoferrin in dose of 100 mg/kg and
Autor:
T. S. Kolesnichenko, T. G. Gor'kova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 115:320-323
Publikováno v:
Voprosy onkologii. 52(1)
It was investigated whether preliminary administration of water with reduced Deuterium content may modify the inhibitory effect of the water given to BDF1 and CDA mice on the day of tumor transplantation. Two models were used: Lewis lung carcinoma (L
Autor:
V S, Turusov, Iu E, siniak, A I, Grigor'ev, D G, Zaridze, E E, Antoshina, L S, Trukhanova, T G, Gor'kova
Publikováno v:
Voprosy onkologii. 51(1)
Such models of transplantable tumors as Lewis sarcoma, uterine sarcoma-322 and uterine carcinoma-5 were used to study possible inhibitory effect by low-deuterium water. Such water was given to experimental animals (20 mice in each group). Controls (3
Autor:
Iu E, Siniak, V S, Turusov, A I, Grigor'ev, D G, Zaridze, V B, Gaĭdadymov, E I, Gus'kova, E E, Antoshina, T G, Gor'kova, L S, Trukhanova
Publikováno v:
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 37(6)
Interplanetary missions, including to Mars, will put crews into severe radiation conditions. Search for methods of reducing the risk of radiation-induced cancer is of the top priority in preparation for the mission to Mars. One of the options is desi