Zobrazeno 1 - 10
of 114
pro vyhledávání: '"T. G. Allen‐Mersh"'
Autor:
A. A. Epenetos, A. P. Zbar, W. A. Kmiot, M. Wadhwa, David Snary, T. G. Allen-Mersh, Elizabeth L. Ross, K. N. Syrigos, Walter F. Bodmer, P. Dilger, Robert W. Wilkinson, H. Thomas
BACKGROUND AND AIMS: The aim was to determine the toxicity, clinical and immune responses to the murine monoclonal anti-carcinoembryonic antigen (CEA) antibody, PR1A3, in patients with advanced colorectal cancer. MATERIALS AND METHODS: Fifteen patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd9c50311b379d894e5246fb90184a8
https://ora.ox.ac.uk/objects/uuid:73d53d8c-0e15-4928-8f27-cd14369f8c2f
https://ora.ox.ac.uk/objects/uuid:73d53d8c-0e15-4928-8f27-cd14369f8c2f
Autor:
A. C. von Roon, James Newman, Shradha Gupta, Joseph F. Fitzgerald, T. G. Allen-Mersh, H. H. Sigurdsson
Publikováno v:
Colorectal Disease. 14:1020-1026
Aim The BLEED criterion is a triaging model for lower gastrointestinal bleeding (LGIB), which was developed and validated in the USA. We assessed the BLEED criteria in a UK population and aimed to elucidate factors that can be implemented for early r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a2419b55713e024426d22f33727163
https://doi.org/10.1111/j.1463-1318.2011.02824.x
https://doi.org/10.1111/j.1463-1318.2011.02824.x
Publikováno v:
British Journal of Surgery. 94:96-105
Background This study assessed the potential for reverse transcriptase–polymerase chain reaction (RT–PCR)-based circulating tumour cell identification to predict colorectal cancer recurrence. Methods mRNA for carcinoembryonic antigen and cytokera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a629afe717e7ff42096def7351061b57
https://doi.org/10.1002/bjs.5526
https://doi.org/10.1002/bjs.5526
Publikováno v:
Clinical and Experimental Immunology. 134:270-278
SUMMARY Cancer-related cytokines may interfere with the differentiation and migration of dendritic cells (DCs) and with the associated up-regulation of co-stimulatory molecules in vitro. We determined whether cytokines affected the distribution and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90c1314488435915ade3ef2f78ae2f8
https://doi.org/10.1046/j.1365-2249.2003.02295.x
https://doi.org/10.1046/j.1365-2249.2003.02295.x
Publikováno v:
British Journal of Cancer
Cancer-related indoleamine (2,3)-dioxygenase up-regulation by interferon-γ might influence quality of life by depleting serum tryptophan. We correlated serum tryptophan levels with immune activation and quality of life in patients with colorectal li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50173a7822965921d2c4ef1e54307cc7
https://doi.org/10.1038/sj.bjc.6600336
https://doi.org/10.1038/sj.bjc.6600336
Publikováno v:
Colorectal Disease. 4:158-161
Sentinel lymph node (SLN) biopsy in colorectal cancer is feasible, and may offer a means of reducing histopathology workload while maintaining staging accuracy. Although SLN biopsy allows use of sensitive molecular markers that can identify isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e484ad4fd6c5dcac7881420b60173e
https://doi.org/10.1046/j.1463-1318.2002.00356.x
https://doi.org/10.1046/j.1463-1318.2002.00356.x
Publikováno v:
Cancer Immunology, Immunotherapy. 51:53-57
It is unclear whether the presence of interleukin-2 soluble receptor alpha (IL-2 sRalpha) in the serum of colorectal cancer patients is solely due to T cell activation. In this study, we therefore investigated whether T cell activation, indicated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50469c86ca202e05a5cce84ae448699f
https://doi.org/10.1007/s00262-001-0250-6
https://doi.org/10.1007/s00262-001-0250-6
Autor:
Hitesh C. Patel, Michael M. Henry, R.Q. Wharton, C Glover, Nadia Le Marer, Ruth Araia, Zulfiqar A. J. Khan, T G Allen-Mersh
Publikováno v:
Annals of Surgery. 235:226-231
Experimental in vivo studies suggest that circulating tumor cells (CTCs) can be detected early in the natural history of solid tumor growth, before the development of metastases. 1 Hematogenous metastasis is thought to be an inefficient process where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb25a4335673cc4db4252691df029cc
https://doi.org/10.1097/00000658-200202000-00010
https://doi.org/10.1097/00000658-200202000-00010
Publikováno v:
Clinical and Experimental Metastasis. 19:495-502
The aim of this study was to determine whether flow cytometry (FACS) could detect spiked or circulating colorectal cancer cells. A flow cytometric assay was developed and its sensitivity compared with the reverse transcription polymerase-chain reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72846e910093ef01b336883dde165980
https://doi.org/10.1023/a:1020350117292
https://doi.org/10.1023/a:1020350117292
Publikováno v:
Acta Oncologica. 41:84-90
Tumour response depends on intratumoural cytotoxic concentration, which varies with tumour vascularity. We determined whether basic fibroblast growth factor (bFGF) infusion increased tumour vascularity, blood flow and cytotoxic drug uptake. The effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de67263e4d8bc0e8cd7141d0852c7f6
https://doi.org/10.1080/028418602317314118
https://doi.org/10.1080/028418602317314118