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Akademický článek

PATIENT-CENTRED SCREENING FOR PRIMARY IMMUNODEFICIENCY, A MULTI-STAGE DIAGNOSTIC PROTOCOL DESIGNED FOR NONIMMUNOLOGISTS: 2011 UPDATE

Publikováno v: Медицинская иммунология, Vol 15, Iss 5, Pp 477-492 (2014)

Abstract. Members of the European Society for Immunodeficiencies (ESID) and other colleagues have updated themulti-stage expert-opinion-based diagnostic protocol for non-immunologists incorporating newly defined primary immunodeficiency diseases (PID

Externí odkaz: https://doaj.org/article/9cb9fdcb7bfa4429832701b902e8a2e1

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Defective Self-Reactive Antibody Repertoire of Serum IgM in Patients with Hyper-IgM Syndrome

Autor: S, Lacroix-Desmazes, I, Resnick, D, Stahl, L, Mouthon, T, Espanol, J, Levy, S V, Kaveri, L, Notarangelo, M, Eibl, A, Fischer, H, Ochs, M D, Kazatchkine

Publikováno v: The Journal of Immunology. 162:5601-5608

We have analyzed the self-reactive repertoires of IgM and IgG Abs in the serum of 19 patients with hyper-IgM syndrome (HIM) by means of a quantitative immunoblotting technique that allows for a quantitative comparison of Ab repertoires in health and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ef6eb4579bd7e356cac7dfed10f42b
https://doi.org/10.4049/jimmunol.162.9.5601

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Identification of a CD40L gene mutation and genetic counselling in a family with immunodeficiency with hyperimmunoglobulinemia M

Autor: M. De Weers, Rudolf W. Hendriks, Ruud K. B. Schuurman, Margriet E. M. Kraakman, T. Espanol

Publikováno v: Clinical Genetics. 48:46-48

A 13-year-old boy with immunodeficiency with hyper-IgM was analyzed for mutations in the CD40L gene. An insertional mutation of an extra T in a run of four T's was found in the second exon of the gene, leading to a premature translation stop. Genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71d34b3f75d0363fc1bfdd62ba64f84
https://doi.org/10.1111/j.1399-0004.1995.tb04053.x

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Expression of c-fos and hsp70 mRNA in neonatal rat cerebrocortical slices during NMDA-induced necrosis and apoptosis

Autor: Lawrence Litt, Maryceline T. Espanol, Pak H. Chan, Frank R. Sharp, Koh Hasegawa

Publikováno v: Brain Research. 785:262-278

Respiring neonatal rat cerebrocortical slices were exposed for 30 min to toxic concentrations of N-methyl-D-aspartate (NMDA; 100 microM, 500 microM and 1000 microM). In situ hybridization was used to study c-fos and hsp70 mRNA before, during, and for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aebf7f14cfadb07cc56aa1942478e03
https://doi.org/10.1016/s0006-8993(97)01410-8

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Preparative methods for brain slices: a discussion

Autor: P. Lipton, G. R. Breese, M. T. Espanol, F. Edwards, P. M. Larkman, K. H. Reid, P. J. Voulalas, M. E. Rice, F. F. Dudek, G. C. Newman, T. J. Teyler, J. M. Sarvey, Peter G. Aitken, K. L. Panizzon, C. P. Taylor, Kathleen M. Raley-Susman, Thaddeus Nowak, M. Segal, D. D. Schoepp

Publikováno v: Journal of Neuroscience Methods. 59:139-149

Criteria for slice health and factors that affect slice health were discussed by many of the participants in the conference. In addition to the standard parameters of slice health (energy metabolism, morphology, electrophysiological responsiveness) m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92514ef6d00d2bcd5699e48bfdc00088
https://doi.org/10.1016/0165-0270(94)00204-t

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19F NMR calcium changes, edema and histology in neonatal rat brain slices during glutamate toxicity

Autor: Lee-Hong Chang, Lawrence Litt, Yan Xu, Pak H. Chan, Philip Weinstein, Maryceline T. Espanol, Thomas L. James

Publikováno v: Brain Research. 647:172-176

Respiring neonatal cerebrocortical slices (350 microns thick), loaded with the free calcium indicator 5F-BAPTA, were perfused in a 20-mm-diameter glass NMR tube with oxygenated artificial CSF, exposed to extracellular glutamate and studied at 4.7 Tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05073b697971f74cd67d7baa5d4c60cc
https://doi.org/10.1016/0006-8993(94)91414-1

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Comparison of lithium ion transport and distribution in human red blood cells in the presence and absence of dysprosium(III) complexes of triphosphate and triethylenetetraminehexaacetate

Autor: Maryceline T. Espanol, Ravichandran Ramasamy, Richard J. Labotka, Duarte Mota de Freitas

Publikováno v: Inorganic Chemistry. 29:3972-3979

Discrimination between intra- and extracellular Li + pools in Li + -loaded human red blood cells (RBCs) was achieved by two distinct 7 Li NMR methods. One NMR method involved the incorporation in the RBC suspension of cell-impermeable shift reagents,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed8ffc9199da1dd0edb9bb7ac3fe5ea4
https://doi.org/10.1021/ic00345a013

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Rapid protein-based assays for the diagnosis of T-B+ severe combined immunodeficiency

Autor: K C, Gilmour, T, Cranston, S, Loughlin, J, Gwyther, T, Lester, T, Espanol, M, Hernandez, G, Savoldi, E G, Davies, M, Abinun, C, Kinnon, A, Jones, H B, Gaspar

Publikováno v: British journal of haematology. 112(3)

The severe combined immunodeficiencies (SCID) are a heterogeneous group of conditions arising from a variety of molecular defects. The X-linked form of SCID (X-SCID) is caused by defects in the common gamma chain (gammac), and is characterized by a T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91f66106049e0c98321653d9ed555ff0
https://pubmed.ncbi.nlm.nih.gov/11260071

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Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives

Autor: I. Caragol, C. Altisent, Arantxa Gutiérrez, L. Puig, B. Clotet, Jordi Barretina, José A. Esté, T. Espanol, Julià Blanco

Publikováno v: Transfusion. 40(4)

BACKGROUND: Overproduction of β-chemokines and genetic variations in chemokine receptors have been correlated with protection against infection by HIV-1 or slow progression to AIDS in infected individuals. STUDY DESIGN AND METHODS: The protective ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b59ebf6e19ad9890e7e2a337274045
https://pubmed.ncbi.nlm.nih.gov/10773060

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