Zobrazeno 1 - 10
of 140
pro vyhledávání: '"T. Ehrlich"'
Autor:
Rita R. Fagan, David F. Lee, Matan Geron, Grégory Scherrer, Mark von Zastrow, Aliza T. Ehrlich
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114164- (2024)
Summary: Opioid receptors are therapeutically important G protein-coupled receptors (GPCRs) with diverse neuromodulatory effects. The functional consequences of opioid receptor activation are known to depend on receptor location in the plasma membran
Externí odkaz:
https://doaj.org/article/bc53921370f5478ea5e16804e7e64541
Autor:
Florence Allain, Aliza T. Ehrlich, Michael McNicholas, Florence Gross, Weiya Ma, Brigitte L. Kieffer, Emmanuel Darcq
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionTianeptine is approved in some countries to treat depression and anxiety. In addition to its activity on serotonin and glutamate neurotransmission, tianeptine has been proven to be a mu-opioid receptor (MOR) agonist, but only a few precli
Externí odkaz:
https://doaj.org/article/fbc1e78565a6457984f10478c201776d
Autor:
Aliza T. Ehrlich, Pierre Couvineau, Selin Schamiloglu, Stefan Wojcik, Dillon Da Fonte, Amina Mezni, Mark von Zastrow, Kevin J. Bender, Michel Bouvier, Brigitte L. Kieffer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Dopamine (DA) neurons are primarily concentrated in substantia nigra (SN) and ventral tegmental area (VTA). A subset of these neurons expresses the neurotensin receptor NTSR1 and its putative ligand neurotensin (Nts). NTSR1, a G protein-coupled recep
Externí odkaz:
https://doaj.org/article/60946e01acc54ad989070a28ad6aa5b1
Autor:
Aliza T. Ehrlich, Meriem Semache, Pierre Couvineau, Stefan Wojcik, Hiroyuki Kobayashi, Marcus Thelen, Florence Gross, Mireille Hogue, Christian Le Gouill, Emmanuel Darcq, Michel Bouvier, Brigitte L. Kieffer
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-23 (2021)
Abstract The atypical chemokine receptor 3, ACKR3, is a G protein-coupled receptor, which does not couple to G proteins but recruits βarrestins. At present, ACKR3 is considered a target for cancer and cardiovascular disorders, but less is known abou
Externí odkaz:
https://doaj.org/article/c691042905314379a42058d6da6d43ec
Autor:
Aliza T. Ehrlich, Meriem Semache, Florence Gross, Dillon F. Da Fonte, Leonie Runtz, Christine Colley, Amina Mezni, Christian Le Gouill, Viktoriya Lukasheva, Mireille Hogue, Emmanuel Darcq, Michel Bouvier, Brigitte L. Kieffer
Publikováno v:
iScience, Vol 14, Iss , Pp 47-57 (2019)
Summary: G protein-coupled receptors are key signaling molecules and major targets for pharmaceuticals. The concept of ligand-dependent biased signaling raises the possibility of developing drugs with improved efficacy and safety profiles, yet transl
Externí odkaz:
https://doaj.org/article/88fbd700e88446eda04c7bc96f781810
Autor:
Maria Zamfir, Behrang Sharif, Samantha Locke, Aliza T. Ehrlich, Nicole E. Ochandarena, Grégory Scherrer, Alfredo Ribeiro-da-Silva, Brigitte L. Kieffer, Philippe Séguéla
Publikováno v:
Pain. 164:703-716
The anterior cingulate cortex (ACC) processes the affective component of pain, whereas the primary somatosensory cortex (S1) is involved in its sensory-discriminative component. Injection of morphine in the ACC has been reported to be analgesic, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae77096ffb681a8e6f43d6c3cfaf92b
https://doi.org/10.1097/j.pain.0000000000002751
https://doi.org/10.1097/j.pain.0000000000002751
Akademický článek
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Publikováno v:
The Thoracic and Cardiovascular Surgeon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a970cd502fd3026659c86615369b8f70
https://doi.org/10.1055/s-0042-1742920
https://doi.org/10.1055/s-0042-1742920
Akademický článek
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