Zobrazeno 1 - 10
of 32
pro vyhledávání: '"T. E. Wagner"'
Publikováno v:
Reproduction. 95:109-118
Reproductive performance was studied in transgenic males from lines expressing and transmitting four hybrid genes: mouse metallothionein-I/human growth hormone (GH) (MT/hGH), MT/hGH placental variant (MT/hGH.V), MT/bovine GH (MT/bGH) and phosphoenolp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fff53d0ee65d04ea036fc6730090ab5
https://doi.org/10.1530/jrf.0.0950109
https://doi.org/10.1530/jrf.0.0950109
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(11)
Human breast cancer is the predominant malignancy and the leading cause of cancer death in women from Western societies. The cause of breast cancer is still unknown. Recently, the association between human prolactin (hPRL) activity and breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0840e33f854e342fa5d3bfa7bc8fed07
https://pubmed.ncbi.nlm.nih.gov/10589775
https://pubmed.ncbi.nlm.nih.gov/10589775
Publikováno v:
Transgenic research. 7(1)
In rodents, bovine (b) growth hormone (GH) binds only to GH receptors, while human (h) GH binds to both GH and PRL receptors. The phenotypic consequences of expression of bGH and hGH in transgenic mice are different and, in some cases, opposite. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caa6146b3b98ca18aabfb1f6d7f841ee
https://pubmed.ncbi.nlm.nih.gov/9556914
https://pubmed.ncbi.nlm.nih.gov/9556914
Publikováno v:
Cancer gene therapy. 2(4)
We recently have developed a unique cytoplasmic transient gene expression system based on cotransfection of target cells with bacteriophage T7 RNA polymerase (RNAP) and plasmid DNA vectors containing a T7 autogene. Because this T7 system is self-init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ec6115d090c7ff0ba1054bdd34c0997
https://pubmed.ncbi.nlm.nih.gov/8548582
https://pubmed.ncbi.nlm.nih.gov/8548582
Publikováno v:
The Journal of biological chemistry. 269(32)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a9ce9c2a433fc88f9ff21b5ae249319
https://pubmed.ncbi.nlm.nih.gov/8051183
https://pubmed.ncbi.nlm.nih.gov/8051183
Publikováno v:
The Journal of biological chemistry. 269(22)
A bovine growth hormone (bGH) analog, bGH-G119R, has been shown to act as a functional antagonist of GH activity both in vitro and in vivo. In the present study, human (h) GH analogs with alterations in the third alpha-helix (G120A, G120R) and N term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a467596f667e06a5f9ee522c31ecb71
https://pubmed.ncbi.nlm.nih.gov/8195244
https://pubmed.ncbi.nlm.nih.gov/8195244
Publikováno v:
Journal of andrology. 15(1)
To determine the effects of testosterone on the regulation of gonadotropins in metallothionein-1/human growth hormone (MT/hGH) transgenic mice, basal and gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) and follicle-stimulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::777289b210223dd4e237d8e2089250fd
https://pubmed.ncbi.nlm.nih.gov/8188541
https://pubmed.ncbi.nlm.nih.gov/8188541
Publikováno v:
Biology of reproduction. 49(2)
Expression of the mouse metallothionein-I (MT) promoter/bovine growth hormone (bGH) or the phosphoenolpyruvate carboxykinase (Pepck) promoter/bGH fusion genes in male transgenic mice is associated with alternations in adenohypophyseal function and fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bf014d1fb77fadf7947d06f96406b96
https://pubmed.ncbi.nlm.nih.gov/8373959
https://pubmed.ncbi.nlm.nih.gov/8373959
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 68(5)
In mice transgenic for growth hormone (GH), the ectopic production of foreign GH causes gigantism and strong inhibition of endogenous pituitary GH. In human (h) GH transgenics, morphologic changes occurred not only in somatotrophs but in lactotrophs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68742f13b899d1afcf0fabdcc95188a1
https://pubmed.ncbi.nlm.nih.gov/8388524
https://pubmed.ncbi.nlm.nih.gov/8388524
Publikováno v:
Endocrinology. 131(1)
Transgenic mice carrying the phosphoenolpyruvate carboxykinase promoter region-human growth hormone (PEPCK-hGH) fusion gene are characterized by accelerated growth and plasma hGH levels ranging from 100 to 700 ng/ml. Both sexes are fertile, in contra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875511027e90503d47ab1d1374e4d549
https://pubmed.ncbi.nlm.nih.gov/1612034
https://pubmed.ncbi.nlm.nih.gov/1612034