Zobrazeno 1 - 10
of 10
pro vyhledávání: '"T. E. Mabry"'
Autor:
E. J. Holsztynska, K. L. Sacchi, L. Z. Chen, J. C. Clemens, I. M. Lieberburg, L. C. Mutter, Bruce D. Gitter, T. C. Britton, C. A. Whitesitt, E. D. Thorsett, L. D. Altstiel, M. H. Bender, K. L. Johnson-Wood, G. M. Shopp, R. N. Motter, B. Folmer, T. E. Mabry, D. Stephenson, S. Yang, B. D. Potts, Binhui Ni, D. B. Schenk, T. Yin, Paul A. Hyslop, Jon K. Reel, K. L. Hu, W.-Y. Li, C. T. Yin, J. E. Knops, P. De Saint Andrieu, V. John, Z. Liao, E. Goldbach, F. D. Miller, L. A. Shipley, J. Wu, E. M. Johnstone, L. H. Latimer, S. B. Freedman, J. P. Anderson, H. F. Dovey, P. A. Seubert, Michael K. Lee, D. K. Dieckman-Mcginty, S. L. Kennedy, J. S. Nissen, Sheila P. Little, Leonard N. Boggs, J. S. Tung, J. Nietz, L. Y. Fang, D. L. Czilli, Patrick C. May, Warren J. Porter, James E. Audia, K. P. Quinn, J. J. Droste, D. Kholodenko, Y. Su, Kimberly S. Fuson
Publikováno v:
Journal of Neurochemistry. 76:173-181
Converging lines of evidence implicate the beta-amyloid peptide (Ass) as causative in Alzheimer's disease. We describe a novel class of compounds that reduce A beta production by functionally inhibiting gamma-secretase, the activity responsible for t
Autor:
T. E. Mabry, J. C. Scheuring, K. K. Richardson, A. J. Baxter, J. M. Colacino, K. A. Staschke, Frank C. Richardson, D. M. Huffman, W. C. Smith
Publikováno v:
Nucleic Acids Research. 24:4111-4116
The thymidine analog, 1-(2-deoxy-2-fluoro-beta-D-arabino-furanosyl)-5-iodouracil (FIAU), is incorporated into DNA in cell culture and in vivo. To investigate the effect of incorporation of FIAU into DNA on the binding of transcription factors, oligon
Autor:
H. L. Pearce, J. M. Colacino, Chou Ta-Sen, C. D. Jones, T. E. Mabry, G. B. Grindey, J. F. Worzalla
Publikováno v:
Nucleosides and Nucleotides. 13:1125-1133
The synthesis of β-dFARPP was accomplished by Mitsunobu coupling of 6-cyanopurine with 2-deoxy-2, 2-difluororibose followed by purine ring-expansion under the action of methanolic ammonia. The title compound inhibited the growth of proliferating hum
Autor:
J. M. Colacino, H. L. Pearce, Chou Ta-Sen, Gerald B. Grindey, Chauncey D. Jones, John F. Worzalla, T. E. Mabry
Publikováno v:
ChemInform. 26
Autor:
H F, Dovey, V, John, J P, Anderson, L Z, Chen, P, de Saint Andrieu, L Y, Fang, S B, Freedman, B, Folmer, E, Goldbach, E J, Holsztynska, K L, Hu, K L, Johnson-Wood, S L, Kennedy, D, Kholodenko, J E, Knops, L H, Latimer, M, Lee, Z, Liao, I M, Lieberburg, R N, Motter, L C, Mutter, J, Nietz, K P, Quinn, K L, Sacchi, P A, Seubert, G M, Shopp, E D, Thorsett, J S, Tung, J, Wu, S, Yang, C T, Yin, D B, Schenk, P C, May, L D, Altstiel, M H, Bender, L N, Boggs, T C, Britton, J C, Clemens, D L, Czilli, D K, Dieckman-McGinty, J J, Droste, K S, Fuson, B D, Gitter, P A, Hyslop, E M, Johnstone, W Y, Li, S P, Little, T E, Mabry, F D, Miller, J E, Audia
Publikováno v:
Journal of neurochemistry. 76(1)
Converging lines of evidence implicate the beta-amyloid peptide (Ass) as causative in Alzheimer's disease. We describe a novel class of compounds that reduce A beta production by functionally inhibiting gamma-secretase, the activity responsible for t
Autor:
Jeffrey A. Kirkwood, D L Hyslop, T E Mabry, B L Hatcher, G D Place, Joyce A. Compton, Ronald R. Bowsher, Karl A. DeSante, C D Jones
Fialuridine (FIAU) is a halogen-substituted analog of thymidine that was undergoing clinical investigation as a drug for the treatment of chronic hepatitis B viral infection. However, clinical trials of FIAU were terminated after adverse events occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5583f9e39b839ea0125fe2f9c0bcd2ca
https://europepmc.org/articles/PMC284697/
https://europepmc.org/articles/PMC284697/
Publikováno v:
Antiviral research. 23(1)
A human hepatoblastoma cell line was stably transfected with a head-to-tail dimer of the Hepatitis B virus (HBV), subtype adw, genome to generate a cell line which produces HBV. FIAU [1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodo)uracil] inh
Autor:
C. Chakrabarty, T. E. Mabry, P. L. Bock, R. W. Stevenson, S. J. Ganion, C. C. Yoder, M. Yao, T. E. Trehearne, B. E. Beeson, S. Barnell, L. R. Sousa, B. Son, S. Pope
Publikováno v:
ACS Symposium Series ISBN: 9780841227286
Fluorescent Chemosensors for Ion and Molecule Recognition
Fluorescent Chemosensors for Ion and Molecule Recognition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e50c59d3c2150c97704f365f8ac9bebb
https://doi.org/10.1021/bk-1993-0538.ch002
https://doi.org/10.1021/bk-1993-0538.ch002
Publikováno v:
Antiviral Research. 26:A291
Autor:
ANTHONY W. CZARNIK, L. R. Sousa, B. Son, T. E. Trehearne, R. W. Stevenson, S. J. Ganion, B. E. Beeson, S. Barnell, T. E. Mabry, M. Yao, C. Chakrabarty, P. L. Bock, C. C. Yoder, S. Pope, Bernard Valeur, Jean Bourson, Jacques Pouget, Richard A. Bissell, A. Prasanna de Silva, H. Q. Nimal Gunaratne, P. L. Mark Lynch, Colin P. McCoy, Glenn E. M. Maguire, K. R. A. Samankumara Sandanayake, H. Bouas-Laurent, J-P. Desvergne, F. Fages, P. Marsau, Akihiko Ueno, Thomas W. Bell, Daniel L. Beckles, Peter J. Cragg, Jia Liu, James Maioriello, Andrew T. Papoulis, Vincent J. Santora, Roger Y. Tsien, Michael A. Kuhn, Divakar Masilamani, Mariann E. Lucas, Grant A. Krafft, Gary T. Wang, H. Szmacinski, J. R. Lakowicz