Zobrazeno 1 - 10 of 40 pro vyhledávání: '"T. E. Emerson"'
1
Study of septic shock in the non-human primate: relationship of pathophysiological response to therapy with anti-TNF antibody
Autor: L B, Hinshaw, T E, Emerson, A C, Chang, M, Duerr, G, Peer, M, Fournel
Publikováno v: Circulatory shock. 44(4)
Therapy with anti-TNF antibody is reported to be effective in preventing morbidity and mortality in baboons given lethal infusions of Escherichia coli. Treated animals survived, and organ histopathology was absent when antibody was administered early
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::853edca8aa27a39e66312d2c3db508d9
https://pubmed.ncbi.nlm.nih.gov/7628065
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2
Lethal Staphylococcus aureus-induced shock in primates: prevention of death with anti-TNF antibody
Autor: L B, Hinshaw, T E, Emerson, F B, Taylor, A C, Chang, M, Duerr, G T, Peer, D J, Flournoy, G L, White, S D, Kosanke, C K, Murray
Publikováno v: The Journal of trauma. 33(4)
A successful experimental treatment for gram-positive sepsis to our knowledge has not been achieved. The objectives of this study were to develop a nonhuman primate model of lethal gram-positive sepsis employing the micro-organism Staphylococcus aure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f95863609afb1c2deeb5de9df008c58b
https://pubmed.ncbi.nlm.nih.gov/1433404
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3
Efficacy of monoclonal antibody against tumor necrosis factor alpha in an endotoxemic baboon model
Autor: T E, Emerson, D C, Lindsey, G J, Jesmok, M L, Duerr, M A, Fournel
Publikováno v: Circulatory shock. 38(2)
Tumor necrosis factor alpha (TNF) has been described as a primary mediator of the pathophysiology associated with bacterial sepsis/endotoxemia. We tested the efficacy and possible mechanisms of protection of a monoclonal antibody against TNF (TNF Mab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0acc1e967697296993233d98f587a76c
https://pubmed.ncbi.nlm.nih.gov/1423924
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4
Characterization of an endotoxemic baboon model of metabolic and organ dysfunction
Autor: D C, Lindsey, T E, Emerson, T E, Thompson, A E, John, M L, Duerr, C M, Valdez, H S, Kuo, R B, Bouffard, R G, Irwin, D, Canivel
Publikováno v: Circulatory shock. 34(3)
An anesthetized endotoxemic baboon model has been developed by infusing 2.0 mg E. coli endotoxin/kg i.v. over 1 hr (n = 7). Animals were monitored for 5-7 days with analyses of: cardiovascular, metabolic, and organ dysfunction; acid base, hemostatic,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::499accc4ccb285edaf75d9b59669cd32
https://pubmed.ncbi.nlm.nih.gov/1653118
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6
Survival of primates in LD100 septic shock following therapy with antibody to tumor necrosis factor (TNF alpha)
Autor: L B, Hinshaw, P, Tekamp-Olson, A C, Chang, P A, Lee, F B, Taylor, C K, Murray, G T, Peer, T E, Emerson, R B, Passey, G C, Kuo
Publikováno v: Circulatory shock. 30(3)
The purpose of this study was to determine the efficacy of treatment with anti-TNF monoclonal antibody in preventing the deleterious effects of sepsis in a nonhuman primate. Experiments were carried out on anesthetized baboons intravenously infused w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c151bae29edb35f4d87eed231ce7d01b
https://pubmed.ncbi.nlm.nih.gov/2178801
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8
Involvement of adenosine in cerebral hypoxic hyperemia in the dog
Autor: T. E. Emerson, R. M. Raymond
Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 241:H134-H138
Theophylline, a competitive adenosine antagonist, was used to evaluate the role of adenosine in cerebral hypoxic hyperemia. Cerebral venous outflow was measured by the Rapela-Green technique in mongrel dogs anesthetized with pentobarbital sodium and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d420722d2e49a31392886456ae50b5
https://doi.org/10.1152/ajpheart.1981.241.2.h134
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