Výsledky vyhledávání - "T. E. Hansen-Hagge"

Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: Suggestion for classification by immunophenotype and T-cell receptor studies

Autor: Martin Gramatzki, T. E. Hansen-Hagge, Renate Burger, Hans G. Drexler

Publikováno v: Leukemia Research. 23:19-27

Hematopoietic cell lines are often used as representatives for a certain cell differentiation lineage and stage, particularly in immunological and hematological studies. Acute lymphoblastic leukemia (ALL) of T-cell type is a rather heterogeneous grou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24610545724cd35007e7e43ce18168d6
https://doi.org/10.1016/s0145-2126(98)00133-7

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In Vitro Culture Studies of Childhood Myelodysplastic Syndrome: Establishment of the Cell Line MUTZ-1

Autor: Suzanne M. Gignac, Hartmut Kabisch, Roderick A.F. MacLeod, Hans G. Drexler, Hilmar Quentmeier, Gerhard Gaedicke, Zhenbo Hu, Dörthe Teepe, Klaus G. Steube, T. E. Hansen-Hagge, D. Harms

Publikováno v: Leukemia & Lymphoma. 25:345-363

Myelodysplastic syndrome (MDS) in childhood is considered to be very rare and detailed pathobiological data are scarce. More biological information regarding MDS in children is clearly needed and in vitro culture studies provide one possibility for g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b40559906183754a72071edb31f844
https://doi.org/10.3109/10428199709114174

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Therapy with CD7 monoclonal antibody TH‐69 is highly effective for xenografted human T‐cell ALL

Autor: Joachim R. Kalden, Helmuth Steininger, Elisabeth Kremmer, Wolfgang Becker, Martin Gramatzki, T. E. Hansen-Hagge, Wolfgang Baum, H. J. Bair, Michael Kressel

Publikováno v: British Journal of Haematology. 95:327-338

Human T-cell acute lymphocytic leukaemia (ALL) was established in athymic nude or severe combined immunodeficient (SCID) mice by injecting CEM or MOLT-16 cells. When nude mice bearing approx. 2 g of tumour were treated with a single injection of CD7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938163bd39819c7a245cfcbfe1edaeac
https://doi.org/10.1046/j.1365-2141.1996.d01-1900.x

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Alternative splicing restricts translation of rearrangements at the T- cell receptor delta/alpha locus

Autor: C. R. Bartram, C. Mahotka, R. E. Panzer-Grümayer, H. J. Reuter, Klaus Schwarz, J. J. M. Van Dongen, T. E. Hansen-Hagge

Publikováno v: Blood. 85:1888-1896

Lymphocytes expressing alpha beta or gamma delta T-cell receptors (TCR) represent distinct T-cell populations. Because TCR delta genes lie within the TCR alpha locus, the rearrangement processes, transcription, and translation of TCR delta or TCR alp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aedf9a46c63ebcb7d9212991ff7544ae
https://doi.org/10.1182/blood.v85.7.1888.bloodjournal8571888

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The acute lymphoblastic leukaemia cell line SEM with t(4;11) chromosomal rearrangement is biphenotypic and responsive to interleukin-7

Autor: Markus Peltner, Renate Burger, Udo Trautmann, Jörn D. Beck, Claus R. Bartram, Rolf Marschalek, Martin Gramatzki, T. E. Hansen-Hagge, Georg H. Fey, Klemens Stehr, Johann Greil

Publikováno v: British Journal of Haematology. 86:275-283

A cell line, designated SEM, was established from the peripheral blood of a 5-year-old girl in relapse with acute lymphoblastic leukaemia (ALL). Both the lymphoblasts of the patient and the cells of the cell line SEM showed the t(4;11) chromosomal re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96396985b572c7a55d2d2f1decbbff3
https://doi.org/10.1111/j.1365-2141.1994.tb04726.x

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Human common acute lymphoblastic leukemia-derived cell lines are competent to recombine their T-cell receptor delta/alpha regions along a hierarchically ordered pathway

Autor: T. E. Hansen-Hagge, S. Yokota, H. J. Reuter, Klaus Schwarz, C. R. Bartram

Publikováno v: Blood. 80:2353-2362

Rearrangements of the T-cell receptor (TCR) delta locus are observed in the majority of human B-cell precursor acute lymphoblastic leukemias (ALL) with a striking predominance of V delta 2(D)D delta 3 recombinations in common ALL (cALL) patients. Rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3af48ca3d7fc570976e149d5bb4d1996
https://doi.org/10.1182/blood.v80.9.2353.2353

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Expansion of a maternally derived monoclonal T cell population with CD3+/CD8+/T cell receptor-gamma/delta+ phenotype in a child with severe combined immunodeficiency

Autor: V Wahn, S Yokota, K L Meyer, J W Janssen, T E Hansen-Hagge, C Knobloch, S Koletzko, H Stein, W Friedrich, C R Bartram

Publikováno v: The Journal of Immunology. 147:2934-2941

The diagnosis of severe combined immunodeficiency complicated by chronic graft-vs-host disease affecting liver and skin in association with engraftment of maternal T cells was established in a 5-mo-old boy. Detailed immunologic and molecular genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::256c024fc941034e932d1676118285fc
https://doi.org/10.4049/jimmunol.147.9.2934

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Molecular genetic analysis of DNA obtained from fixed, air dried or paraffin embedded sources

Autor: J. Lyons, C. R. Bartram, J. W. G. Janssen, T. E. Hansen-Hagge, Hans Feichtinger, Kurt Grünewald

Publikováno v: Annals of Hematology. 62:108-114

In the present study methods are described for the analysis of the genomic structure of DNA isolated from tissues that have been stored up to several years as air-dried or stained bone marrow smears, bone marrow biopsies in "Histicon", chromosomal pr

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https://doi.org/10.1007/bf01702923

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Use of polymerase chain reactions to monitor minimal residual disease in acute lymphoblastic leukemia patients

Autor: Anand Raghavachar, Wolf-Dieter Ludwig, T. E. Hansen-Hagge, Claus R. Bartram, Enno Kleihauer, S. Yokota, Alfred Reiter

Publikováno v: Blood. 77:331-339

T-cell receptor (TCR) delta gene rearrangements are observed in more than 80% of acute lymphoblastic leukemia (ALL) patients. Moreover, a preferential usage of specific genetic elements has been shown in different ALL subtypes: V delta 1 DJ delta 1 r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebdfad161c6f423954f6bb696438960f
https://doi.org/10.1182/blood.v77.2.331.331

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T-cell receptor delta gene recombination in common acute lymphoblastic leukemia: preferential usage of V delta 2 and frequent involvement of the J alpha cluster

Autor: T. E. Hansen-Hagge, C. R. Bartram, S. Yokota

Publikováno v: Blood. 77:141-148

A high frequency (greater than 80%) of acute lymphoblastic leukemias (ALL) exhibit a recombination of the T-cell receptor (TCR) delta chain locus. Interestingly, distinct TCR delta elements are preferentially used in immunologic subtypes. In a recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d68cdc9935e2156634df1983593a895
https://doi.org/10.1182/blood.v77.1.141.bloodjournal771141

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