The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers

Autor: Stefan J. Jodl, Wouter tenVoorde, Stefan Klein, Andrea Wagenfeld, Frank S. Zollmann, Maximilian Feldmüller, Naomi B. Klarenbeek, Digna T. deBruin, Manon A. A. Jansen, Robert Rissmann, Beate Rohde, Matthijs Moerland

Publikováno v: Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)

Abstract This study evaluated and characterized the pharmacological activity of the orally administered interleukin‐1 receptor‐associated kinase 4 (IRAK4) inhibitors BAY1834845 (zabedosertib) and BAY1830839 in healthy male volunteers. Participant

Externí odkaz: https://doaj.org/article/89d49a01219946438e0011ce97dc1147

Abstracts of papers presented at the 14th conference of the Weed Science Society of Israel Abstracts of papers presented at the international conference on controlled atmosphere and fumigation (CAF) in stored products Abstracts of papers presented at the joint international conference of FAOPMA — CEPA on pest control in the 21st century Abstracts of papers presented at the 2nd international Agro-Ecology Symposium on integrated pest management: from the drawing board to the market

Autor: E. Yogev, M. Berson, Y. Benyamini, Y. Sheinboim, T. Lev-Ran, A. Bahat, Y. Barkai, Y. Gatti, M. Zaidan, O. Barazani, Y. Boshvize, S. Graph, U. Luchinsky, T. Blumenfeld, Y. Kleifeld, G. Herzlinger, H. Bucsbaum, S. Golan, T. Chilf, R. Aly, Y. Ohali, A. Ovadia, Y. Chachlon, H. Yovel, Y. Tesler, G. Colodney, A. Nir, S. Zarka, A. Tal, B. Rubin, T. Yaacoby, Y. Alon, Y. Kedar, Orit Ben-Zvi Assaraf, O. Shainberg, H. D. Rabinowitch, E. Tel-Or, Y. Goldwasser, D. M. Joel, D. Plakhine, V. Portnoy, G. Tzuri, N. Katzir, Dalia Losner-Goshen, A. M. Mayer, R. Jacobsohn, Z. Tanaami, H. Eisenberg, Ziva Amsellem, Z. Kernyi, L. Hornok, J. Gressel, Adiva Shomer-Ilan, Ela Nir, Daphna Michaeli, V. Kampel, A. Warshawsky, M. Yogev, M. Negbi, J. Hershenhorn, Y. Lavan, T. Hilf, M. Horowitz, M. Cohen, I. Hirsch, A. Veneziani, S. T. Conyers, C. H. Bell, Ana C. Sá-Fischer, C. S. Adler, Ch. Reichmuth, P. W. Flinn, D. W. Hagstrum, G. N. Mbata, R. G. Winks, Elisabeth A. Hyne, M. Q. Chaudhry, A. D. MacNicoll, N. R. Price, M. Schöller, J. -F. Dugast, R. Plarre, S. Navarro, E. J. Donahaye, R. Diaz, Miriam Rindner, A. Azrieli, P. Trematerra, F. Fontana, M. Mancini, Ailsa D. Hocking, Marta H. Taniwaki, J. Lacey, A. Hamer, N. Magan, N. Paster, F. M. Caliboso, D. G. Alvindia, G. C. Sabio, M. T. dela Cruz, Okky Setyawati Dharmaputra, A. S. R. Putri, M. Sidik, Eleni Papademetriou, A. Varnava, C. Mouskos, M. A. Malek, B. Parveen, K. A. Dzisi, W. O. Ellis, Ana Maria Estevez, Ljubica Galletti, T. Fichet, E. Oteiza, L. A. Lizana, M. X. Gonzalez, B. Yakobson, Y. Slavezky, H. Ephrati, El-H. Bartaly, R. K. Kashyap, M. Gupta, W. L. Kashyap, B. S. Dahiya, A. K. Dash, J. R. Rangaswamy, R. D. Shroff, D. S. Jayas, W. E. Muir, N. D. G. White, L Gaye, null Weller, J. E. van S. Graver, Wu-Kang Peng, M. Bengston, E. Alip, C. Reed, J. G. Leesch, G. F. Knapp, G. F. Russell, L. B. Llewellin, Ch. Ulrichs, H. J. Banks, P. C. Annis, R. Allanson, R. Tauscher, K. Westphal, S. Mohan, M. Gopalan, P. C. Sumdarababu, V. V. Sree Narayanan, Sabine Prozell, G. Ziegleder, B. Schartmann, R. Matissek, J. Kraus, D. Gerard, S. Rogg, W. Raemann, R. F. Ryan, Ya-Nan Wang, R. T. Noyes, P. Kenkel, J. T. Criswell, G. W. Cuperus, C. J. Waterford, C. P. Whittle, L. Benzing, S. Ball, T. DeBruin, C. R. Newman, S. J. Hilton, B. W. Bridgeman, R. J. Hodges, M. Smith, A. Madden, D. Russell, H. Halid, J. L. Zettler, Perlina D. Sayaboc, A. J. O. Gibe, S. Ignatowicz, S. Oboza, C. Slusarski, P. J. Collins, F. A. El-Lakwah, A. A. Darwish, M. M. Khattab, A. M. Abdel-Latif, R. N. Emery, S. Pratt, C. Waterford, A. L. Clifton, K. A. Mills, T. J. Wontner-Smith, G. Khair, W. S. Magee, R. T. Baker, R. W. D. Taylor, J. Klijnstra, R. T. Ross, M. Kostokovski, Valérie Ducom, Julie A. Cassells, R. H. Burton, S. Bhadrikaju, R. L. Meagher, R. Wilkin, C. van Natto, V. Stejskal, P. M. Cogan, N. G. Gratz, U. Shalom, Hedva Pener, A. G. Havron, Z. Klein, H. Adler, S. Moran, A. Wilamowski, R. Amichai, D. K. Mueller, M. Spiegelstein, E. Shaaya, M. Kostjukovski, N. Cooper, M. Coll, S. Steinberg, E. Ravins, W. Waldner, R. Ausher, Y. Rössler, H. Denzer, E. Dunkelblum, M. Kehat

Publikováno v: Phytoparasitica. 24:199-265

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53cf026bf5320ce36ecec1a2d4c62a9d
https://doi.org/10.1007/bf02981419

Analysis of the humoral immune response using combinatorial phage display libraries

Autor: J Vanderheijden, T Debruin, J Dekruif, T Logtenberg

Publikováno v: Immunology Methods Manual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7571f0e6677de367c60030357c3972
https://doi.org/10.1016/b978-012442710-5/50113-1

Editorial

Autor: G BLIJHAM, T DEBRUIN, A HOEPELMAN

Publikováno v: The Netherlands Journal of Medicine. 50:1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e5f2de215756b002673a666c9944a1c
https://doi.org/10.1016/s0300-2977(96)00087-3

Quantitative EEG changes in the human menstrual cycle

Autor: A A, Sugerman, A T, DeBruin, C W, Roth

Publikováno v: Research communications in chemical pathology and pharmacology. 1(4)

Quantitative EEG amplitude analysis was used to study electroencephalographic changes occurring over the course of the human menstrual cycle in 15 normal subjects who were not on any medication and 8 subjects who had been receiving hormonal oral cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2fe8c140960570106bab0ea1461225c2
https://pubmed.ncbi.nlm.nih.gov/5535650