Výsledky vyhledávání

Teaching Aldehydes New Tricks Using Rhodium- and Cobalt-Hydride Catalysis

Autor: Vy M. Dong, Erin L. Kuker, Ryan T Davison

Publikováno v: Accounts of chemical research, vol 54, iss 5
Acc Chem Res

By using transition metal catalysts, chemists have altered the ‘logic of chemical synthesis’ by enabling the functionalization of carbon-hydrogen bonds, which have traditionally been considered inert. Within this framework, our laboratory has bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e5683d43b4939386063057da3e7e8e
https://doi.org/10.1021/acs.accounts.0c00771

Zobrazit plný text záznamu

Predictors and associations of the persistent airflow limitation phenotype in asthma: a post-hoc analysis of the ATLANTIS study

Autor: Tessa M Kole, Elise Vanden Berghe, Monica Kraft, Judith M Vonk, Martijn C Nawijn, Salman Siddiqui, Kai Sun, Leonardo M Fabbri, Klaus F Rabe, Kian Fan Chung, Gabriele Nicolini, Alberto Papi, Chris Brightling, Dave Singh, Thys van der Molen, Sven-Erik Dahlén, Alvar Agusti, Rosa Faner, Jadwiga A Wedzicha, Gavin C Donaldson, Ian M Adcock, Lies Lahousse, Huib A M Kerstjens, Maarten van den Berge, P. Badorrek, M. Broeders, W.G. Boersma, A. Chetta, A. Cukier, M. D'Amato, R. Djukanovic, M.P. Foschino, C. Gessner, N. Hanania, R. Martin, S. Milleri, R. Olivenstein, P. Paggiaro, E. Pizzichini, V. Plaza Moral, D.S. Postma, N. Scichilone, R. Schilz, A. Spanevello, R. Stelmach, J.S. Vroegop, O.S. Usmani, Q. Zhang, H. Ahmed, D. Allen, S. Ballereau, M.K. Batuwitage, A. Bedding, A.F. Behndig, A. Berglind, A. Berton, J. Bigler, M.J. Boedigheimer, K. Bønnelykke, P. Brinkman, A. Bush, D. Campagna, C. Casaulta, A. Chaiboonchoe, T. Davison, B. De Meulder, I. Delin, P. Dennison, P. Dodson, L. El Hadjam, D. Erzen, C. Faulenbach, K. Fichtner, N. Fitch, E. Formaggio, M. Gahlemann, G. Galffy, D. Garissi, T. Garret, E. Guillmant-Farry, E. Henriksson, U. Hoda, J.M. Hohlfeld, X. Hu, A. James, K. Johnson, N. Jullian, G. Kerry, M. Klüglich, R. Knowles, J.R. Konradsen, K. Kretsos, L. Krueger, A-S. Lantz, C. Larminie, P. Latzin, D. Lefaudeux, N. Lemonnier, L.A. Lowe, R. Lutter, A. Manta, A. Mazein, L. McEvoy, A. Menzies-Gow, N. Mores, C.S. Murray, K. Nething, U. Nihlén, R. Niven, B. Nordlund, S. Nsubuga, J. Pellet, C. Pison, G. Praticò, M. Puig Valls, K. Riemann, J.P. Rocha, C. Rossios, G. Santini, M. Sagi, S. Scott, N. Sehgal, A. Selby, P. Söderman, A. Sogbesan, F. Spycher, S. Stephan, J. Stokholm, M. Sunther, M. Szentkereszty, L. Tamasi, K. Tariq, S Valente, W.M. Van Aalderen, C.M. Van Drunen, J. Van Eyll, A. Vyas, W. Yu, W. Zetterguist, Z. Zolkipli, A.H. Zwinderman, A. Agusti, J.A. Wedzicha, G.C. Donaldson, R. Faner, R. Breyer-Kohansal, A.H. Maitland-van der Zee, E. Melén, J.P. Allinson, L.E.G.W. Vanfleteren, J. Vestbo, I.M. Adcock, L. Lahousse, M. Van den Berge, P. Alter, F. Barbe, C.E. Brightling, M.K. Breyer, O.C. Burghuber, M. Casas, K.F. Chung, B.G. Cosío, F. Crispi, J. De Batlle, J.W. Fitting, J. Garcia, J. Hallberg, S. Hartl, D. Jarvis, A. Mathioudakis, L. Nicod, A. Papi, A. Ritchie, T. Sigsgaard, P.J. Sterk, A. Ullman, K. Vellvé, C. Vogelmeier, A.M. Wheelock, C.E. Wheelock

Publikováno v: The Lancet Respiratory Medicine, 11(1), 55-64. Elsevier Limited
The Lancet. Respiratory Medicine, 11(1), 55-64. ELSEVIER SCI LTD
LANCET RESPIRATORY MEDICINE

BACKGROUND: Persistent airflow limitation (PAL) occurs in a subset of patients with asthma. Previous studies on PAL in asthma have included relatively small populations, mostly restricted to severe asthma, or have no included longitudinal data. The a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398c06c4dcd6d075885b6472a2c74e3f
http://hdl.handle.net/10044/1/98623

Zobrazit plný text záznamu

Synthesis and Biological Evaluation of a Depsipeptidic Histone Deacetylase Inhibitor via a Generalizable Approach Using an Optimized Latent Thioester Solid-Phase Linker

Autor: Leila Peraro, Sigrid Carle, Xiaoyu Zang, Heli K. Shah, Ryan T. Davison, Travis R. Blum, David J. Slade, Deepak Vallabhaneni, Caitlyn E. Fennell, Kathryn E. Cole, Matthew R. Burnett, Justin S. Miller, Deirdre M. Wholly, Kathryn M. Ingalls, Jacob T. Sivak, Vernon E. Lawson, Elissa A. Fink, Stephanie L. Cramer, Chelsea T. Herr

Publikováno v: The Journal of Organic Chemistry. 85:8253-8260

We describe the synthesis of Xyzidepsin, a depsipeptidic analogue of HDAC inhibitor Romidepsin (FK228), using a solid-phase strategy. Our latent thioester solid-phase linker was synthesized in 92% yield (three steps). Chemoselective conditions unmask

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d336d3c2d41912dc2b9df760e904381
https://doi.org/10.1021/acs.joc.0c00854

Zobrazit plný text záznamu

Innovative Approaches for Long Term Care

Autor: T. Davison, H. Jayaram, D. Koder, B. Knight, K. Laidlaw, S. Bhar

Publikováno v: Reference Module in Neuroscience and Biobehavioral Psychology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9059cf9194d3ecc43983d4d27d5bfdf
https://doi.org/10.1016/b978-0-12-818697-8.00107-2

Zobrazit plný text záznamu

Unmasking latent thioesters under hydrophobic‐compatible conditions

Autor: Gregory B. Shelkey, Grace E. Hutton, Wade S. Perkins, Vernon E. Lawson, Ryan T. Davison, Justin S. Miller

Publikováno v: Journal of Peptide Science. 27

Hydrophobic latent C-terminal thioesters were converted into thioesters, and were also coupled with cysteine in one-pot reactions, using conditions generally compatible with hydrophobic materials. The reaction conditions (ethanethiol and triethylamin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3f347fa90664828611edc0c16c8bdc
https://doi.org/10.1002/psc.3358

Zobrazit plný text záznamu

Catalytic Hydrothiolation: Counterion-Controlled Regioselectivity

Autor: Shao-Zhen Nie, Xiao-Hui Yang, Vy M. Dong, Faben A. Cruz, Ryan T Davison, Tristan M. McGinnis

Publikováno v: Journal of the American Chemical Society. 141:3006-3013

In this article, we expand upon the catalytic hydrothiolation of 1,3-dienes to afford either allylic or homoallylic sulfides with high regiocontrol. Mechanistic studies support a pathway where regioselectivity is dictated by the choice of counter-ion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9835ea3a50535261f9413e0a86edc11
https://doi.org/10.1021/jacs.8b11395

Zobrazit plný text záznamu

Ready for EURONEAR NEA surveys using the NEARBY moving source detection platform

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
New Astronomy, 88:101600. ELSEVIER SCIENCE BV

Full list of authors: Vaduvescu, O.; Gorgan, D.; Copandean, D.; Bacu, V.; Stefanut, T.; Sabou, A.; Nandra, C.; Boldea, C.; Pinter, V.; Popescu, M.; Petrescu, E.; Bertesteanu, D.; Davison, T.; Pérez Toledo, F. M.; Boldea, A.; Predatu, M.; Zegmott, T.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa898506dee5fc184506047d94fdbf9
http://hdl.handle.net/10261/256624

Zobrazit plný text záznamu

Enantioselective Addition of α-Nitroesters to Alkynes

Autor: Ryan T Davison, Xintong Hou, Vy M. Dong, Patrick D Parker, Sara A Augustine, Crystal P. Chung

Publikováno v: Angew Chem Int Ed Engl

By using Rh-H catalysis, we couple α-nitroesters and alkynes to prepare α-amino acid precursors. This atom-economical strategy generates two contiguous stereocenters, with high enantio- and diastereocontrol. In this transformation, the alkyne under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8dd1c6d933c238610df9c0c803466d
https://pubmed.ncbi.nlm.nih.gov/33411337

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání