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pro vyhledávání: '"T. D. Randall"'
Publikováno v:
Molecular and Cellular Biology. 13:3929-3936
Interleukin-5 (IL-5) and IL-6 have both been reported to act as B-cell differentiation factors by stimulating activated B cells to secrete antibody. However, it has not been possible to directly compare the effects of these two lymphokines because of
Publikováno v:
The Journal of Immunology. 150:78-86
The open reading frames of the 3' long terminal repeat of mouse mammary tumor viruses (MMTV) encode superantigens. When expressed with MHC class II molecules on the surface of B cells, superantigens stimulate T cells expressing receptors with particu
Autor:
D A, Cockayne, T, Muchamuel, J C, Grimaldi, H, Muller-Steffner, T D, Randall, F E, Lund, R, Murray, F, Schuber, M C, Howard
Publikováno v:
Blood. 92(4)
CD38 is a membrane-associated ecto-nicotinamide adenine dinucleotide (NAD+) glycohydrolase that is expressed on multiple hematopoietic cells. The extracellular domain of CD38 can mediate the catalysis of NAD+ to cyclic adenosine diphosphoribose (cADP
Autor:
T D, Randall, I L, Weissman
Publikováno v:
Blood. 89(10)
A significant fraction of hematopoietic stem cells (HSCs) have been shown to be resistant to the effects of cytotoxic agents such as 5-fluorouracil (5-FU), which is thought to eliminate many of the rapidly dividing, more committed progenitors in the
Publikováno v:
The Journal of biological chemistry. 269(25)
The predominant functions of secreted IgM, complement fixation and transcytosis across epithelial barriers via the poly(Ig) receptor, are properties of IgM polymers; thus, the mechanisms that regulate oligomerization are critical to immune function.
Publikováno v:
SPIE Proceedings.
During the fabrication and field installation of fiber optic cables, a combination of torsion and tension may result in premature failure of optical fibers. In this paper, we examine changes to the fracture stress of fibers due to externally applied
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 150(1)
The open reading frames of the 3' long terminal repeat of mouse mammary tumor viruses (MMTV) encode superantigens. When expressed with MHC class II molecules on the surface of B cells, superantigens stimulate T cells expressing receptors with particu
Publikováno v:
Seminars in immunology. 4(5)
Mouse mammary tumor proviruses (MMTV) use a common enhancer/promoter region to accommodate their transcription in two different cellular environments. In mammary tissue, transcription is regulated through the hormone response element located in the 5
Publikováno v:
The Journal of biological chemistry. 267(25)
IgM is secreted in two functional polymeric forms. Secreted IgM was originally thought to be exclusively a pentameric molecule containing J (joining) chain, but many B cells also secrete hexameric IgM lacking J chain. Hexameric IgM may play an import