Zobrazeno 1 - 10
of 23
pro vyhledávání: '"T. D. Bjornsson"'
Autor:
T. D. Bjornsson
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 22:1-14
This article summarizes the practical uses of the six key pharmacokinetic parameters, i.e. elimination half-life, volume of distribution, total clearance, fraction of administered dose eliminated by the kidneys, free fraction in plasma, and bioavaila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d0ff41613584412276f555247452b0
https://doi.org/10.1007/bf03189779
https://doi.org/10.1007/bf03189779
Autor:
P. Wilson, Andrew Zalewski, David C. Levin, Sheldon Goldberg, B. Bravette, Donald Nardone, T. D. Bjornsson, Yi Shi, David L. Fischman, P. Weinstock
Publikováno v:
Circulation. 83:1685-1691
BACKGROUND The goal of this study was to evaluate the role of the fibrinolytic system in patients with unstable angina at rest associated with transient electrocardiographic changes. METHODS AND RESULTS Tissue plasminogen activator activity in plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a35b67f0620305c2e4364aace6ec7c
https://doi.org/10.1161/01.cir.83.5.1685
https://doi.org/10.1161/01.cir.83.5.1685
Autor:
K M Wolfram, T D Bjornsson
Publikováno v:
European Journal of Clinical Pharmacology. 21:491-497
The significance of baseline coagulation times and plasma concentrations of serine protease inhibitors as determinants of the relationship between heparin activity and its anticoagulant effect has been investigated in vitro. Citrated plasma was prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144264dec572dec4775785429293fe72
https://doi.org/10.1007/bf00542044
https://doi.org/10.1007/bf00542044
Publikováno v:
Journal of Vascular Surgery. 8:623-633
The efficacies of standard heparin (SH), low molecular weight heparin (LMWH), and a mixture of sulfated glycosaminoglycans (Org 10172) were investigated with respect to their inhibitory effects on intimal thickening after endothelial injury in the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ec5b0253f366850035fe63b775b078
https://doi.org/10.1067/mva.1988.avs0080623
https://doi.org/10.1067/mva.1988.avs0080623
Publikováno v:
Journal of Clinical Investigation. 75:1591-1599
To resolve questions of drug actions, efficacy, and interactions for platelet-modifying agents used clinically, we have compared the relative capacities and mechanisms of aspirin, dipyridamole, sulfinpyrazone, and dazoxiben to prevent arterial thromb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d12c783579df38e73e717d62ca3622
https://doi.org/10.1172/jci111865
https://doi.org/10.1172/jci111865
Publikováno v:
Biochemical Journal. 262:633-641
Bovine aortic endothelial cells contain Ca2+-dependent tissue-type transglutaminase. Its activity in these cells was high, with apparent Km and Vmax. values with respect to putrescine of 0.203 mM and 18.5 nmol/min per mg of protein, and its activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a770ba31afc820f7dc7a055bfb289826
https://doi.org/10.1042/bj2620633
https://doi.org/10.1042/bj2620633
Autor:
T D, Bjornsson, G, Levy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 210(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b339eaad727fa00a918f909bbd04ec91
https://pubmed.ncbi.nlm.nih.gov/458630
https://pubmed.ncbi.nlm.nih.gov/458630
Publikováno v:
Journal of chromatography. 137(1)
A rapid, sensitive and specific high-pressure liquid chromatographic method is described for the quantitative analysis of clofibrinic acid in plasma, saliva and urine. In contrast to previously reported gas-liquid chromatographic methods, which requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::181382ff39b78aa89bd3cd02b1b080e1
https://pubmed.ncbi.nlm.nih.gov/893579
https://pubmed.ncbi.nlm.nih.gov/893579
Publikováno v:
Cancer treatment reports. 69(12)
Diaziquone (AZQ) is a benzoquinone derivative exhibiting significant effects against CNS tumors. This study investigates the pharmacokinetics of AZQ for three different durations of continuous iv infusions, over 20 mins, 4 hrs, and 6 hrs, in nine pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e513edb5dfa98e9a563225323d965d89
https://pubmed.ncbi.nlm.nih.gov/4075314
https://pubmed.ncbi.nlm.nih.gov/4075314
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 11(1)
The pharmacokinetics and metabolism of a single dermal 20.0 mg/kg of uniformly phenyl-labeled [14C]EPN (O-ethyl O-4-nitrophenyl [14C]phenylphosphonothioate) were investigated in adult male cats. Three treated cats were killed at each time interval: 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a1e989e9a8559c60f732d54db6100f4
https://pubmed.ncbi.nlm.nih.gov/6132792
https://pubmed.ncbi.nlm.nih.gov/6132792