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Autor:
Carol Hopkins Sibley, James G. Kublin, Zul Premji, T. Christian Happi, William M. Watkins, Ali Alloueche, Sarah J. Bates, Juma Bwika, Peter G. Kremsner, Peter Winstanley
Publikováno v:
The Journal of Infectious Diseases. 190:1783-1792
In eastern and southern Africa, there has been a rapid increase in the prevalence of alleles with mutations in the Plasmodium falciparum dihydrofolate reductase gene (dhfr) associated with increased risk of clinical failure of sulfadoxine-pyrimethami