Zobrazeno 1 - 10
of 19
pro vyhledávání: '"T. Chandramohan Reddy"'
Autor:
Chandrani Achari, T. Chandramohan Reddy, V. Lakshmipathi, Gorla V. Reddy, A. Subramanyam, A. Aparna, D. Bharat Reddy, Geetika Gupta, Pallu Reddanna, Kalle M. Arunasree
Publikováno v:
Toxicology in Vitro. 26:396-405
Gallic acid (GA) induces apoptosis in various cancer cell lines. In this study, we investigated the apoptotic activity induced by GA on chronic myeloid leukemia (CML) cell line-K562 and the underlying mechanism. GA reduced the viability of K562 cells
Autor:
P. Ramu Sridhar, Pallu Reddanna, Polamarasetty Aparoy, Chandrani Achari, Nimmanapalli P. Reddy, T. Chandramohan Reddy
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:5807-5815
Ten novel mono- and di-O-prenylated chalcone derivatives were designed on the basis of a homology derived molecular model of 5-lipoxygenase (5-LOX). The compounds were docked into 5-LOX active site and the binding characteristics were quantified usin
Autor:
Pallu Reddanna, M.K. Arunasree, Karnati R. Roy, Devalraju Sreekanth, Gorla V. Reddy, T. Chandramohan Reddy
Publikováno v:
Phytomedicine. 14:739-746
Betalains are water-soluble nitrogenous vacuolar pigments present in flowers and fruits of many caryophyllales with potent antioxidant properties. In the present study the antiproliferative effects of betanin, a principle betacyanin pigment, isolated
Publikováno v:
Journal of Social Sciences. 5:193-199
On widowhood an individual’s living arrangement gains significance as it provides an opportunity for support and has an edge in specific areas of support due to close physical proximity. In Indian ...
Publikováno v:
The Anthropologist. 2:153-159
Autor:
K Anil, Kumar, T Chandramohan, Reddy, Gorla V, Reddy, D Bharat Kumar, Reddy, S V K, Mahipal, Sudhir, Sinha, Anil N, Gaikwad, P, Reddanna
Publikováno v:
Indian journal of biochemistrybiophysics. 48(4)
High-throughput screening (HTS) involves testing of compound libraries against validated drug targets using quantitative bioassays to identify 'hit' molecules that modulate the activity of target, which forms the starting point of a drug discovery ef
Autor:
Chandrani Achari, Polamarasetty Aparoy, T. Chandramohan Reddy, Pallu Reddanna, P. Ramu Sridhar, Nimmanapalli P. Reddy
Publikováno v:
European journal of medicinal chemistry. 47(1)
A group of 4-(benzyloxy)-1-phenylbut-2-yn-1-ol derivatives were designed using Site point connection method, synthesized and evaluated for their 5-Lipoxygenase (5-LOX) inhibitory activity. Hydrophobic site points in 5-LOX were considered for the stud
Autor:
Suresh K. Kalangi, Pallu Reddanna, Kakularam Kumar Reddy, T. Chandramohan Reddy, Polamarasetty Aparoy
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(3)
Inhibitors of the 5-Lipoxygenase (5-LOX) pathway have a therapeutic potential in a variety of inflammatory disorders such as asthma. In this study, chemical feature based pharmacophore models of inhibitors of 5-LOX have been developed with the aid of
Akademický článek
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Akademický článek
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