Zobrazeno 1 - 10
of 72
pro vyhledávání: '"T. C. Spelsberg"'
Autor:
T C Spelsberg, Terry M. Therneau, George M. Farrow, Michael M. Lieber, Ofer Nativ, D S Colvard, T Umehara
Publikováno v:
European Urology. 32:96-99
Objective: To evalute the relationship between the nuclear DNA content and the tissue estrogen receptor (ER) level in patients with operable adenocarcinoma of the prostate. Method: Surgical specimens taken from 73 patients with clinically localized p
Autor:
T. C. Spelsberg, Stuart R. Stock, Nalini M. Rajamannan, Yan Chen, Mahesh Polavarapu, S. Malayannan, Rehan Riaz, Erin L. Hsu, Ming Zhang, Wellington K. Hsu
Publikováno v:
Developments in X-Ray Tomography VII.
The world-wide explosion of commercial microComputed Tomography (microCT) system emplacement has led to dayin, day-out access to laboratory scanners. Most biologically-oriented microCT facilities must characterize large numbers of samples rapidly at
Autor:
F, Chytil, T C, Spelsberg
Publikováno v:
Nature: New biology. 233(41)
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 263:E724-E729
Total cellular RNA was extracted from bone cells of three different femoral compartments of 2-mo-old rats. The intact femora were first incubated with collagenase to obtain periosteal cells. The bisected periosteum-free diaphyses and metaphyses were
Publikováno v:
Journal of musculoskeletalneuronal interactions. 3(4)
Publikováno v:
Endocrinology. 141(12)
The one or more molecular mechanisms that determine the obligatory sequence of resorption followed by formation during bone remodeling is unclear. RANK ligand (RANK-L) is an essential requirement for osteoclastogenesis, and its activity is neutralize
Autor:
G G, Reinholz, B, Getz, L, Pederson, E S, Sanders, M, Subramaniam, J N, Ingle, T C, Spelsberg
Publikováno v:
Cancer research. 60(21)
Bisphosphonates are widely used clinically to treat bone diseases in which bone resorption is in excess. However, the mechanism of bisphosphonate action on bone is not fully understood. Studies of direct action of bisphosphonates on bone have been li
Publikováno v:
Journal of cellular biochemistry. 78(3)
Select members of the TGF-beta family of cytokines play key regulatory roles in skeletal development, structure, and turnover. This laboratory has previously reported that TGF-beta treatment of immortalized normal human fetal osteoblast (hFOB) cells
Publikováno v:
Journal of cellular biochemistry.
The many recent and exciting advances that have taken place in the field of estrogen action on the skeleton are the subjects of this review. Leading these new developments is the discovery of alternative estrogen receptors that exhibit differential m
Publikováno v:
Cancer research. 59(22)
Metastatic breast cancer causes destruction of significant amounts of bone, and, although bone is the most likely site of breast cancer metastasis, little is understood about interactions between tumor cells and bone-resorbing osteoclasts. We have in