Výsledky vyhledávání - "T. C. Merigan"

Characterization of HLA-A 0201-restricted cytotoxic T cell epitopes in conserved regions of the HIV type 1 gp160 protein

Autor: M Dupuis, S K Kundu, T C Merigan

Publikováno v: The Journal of Immunology. 155:2232-2239

CTL activity is a major component of the host immune response associated with control of HIV replication in the course of infection. Emerging populations of HIV overcome the protective effector mechanisms with variant sequences unrecognized by CTL. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3595f4ae7baeed6f180be987d0353c11
https://doi.org/10.4049/jimmunol.155.4.2232

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Antiviral activity and dose optimum of recombinant macrophage colony-stimulating factor on herpes simplex genitalis in guinea pigs

Autor: R J Ho, K T Chong, T C Merigan

Publikováno v: The Journal of Immunology. 146:3578-3582

The antiviral activity of recombinant human macrophage CSF (M-CSF) against genital herpes simplex virus type-2 (HSV-2) infection in guinea pigs was investigated. M-CSF stimulates proliferation of human and guinea pig peripheral blood monocytes, speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56a58d670fe11ebcb48f1c81bd2ecc87
https://doi.org/10.4049/jimmunol.146.10.3578

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Zidovudine (azido dideoxythymidine) inhibits characteristic early alterations of lymphoid cell populations in retrovirus-induced murine AIDS

Autor: D Portnoi, A M Stall, D Schwartz, T C Merigan, L A Herzenberg, T Basham

Publikováno v: The Journal of Immunology. 144:1705-1710

Using flow cytometry technology and multiparameter analyses, we report early and characteristic alterations in lymphoid cell profile in spleen and lymph nodes due to LP-BM5 retrovirus disease (murine AIDS (MAIDS)) and the effect of azido dideoxythymi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81776de61f5ac1ef0e69dc1f01f44fb8
https://doi.org/10.4049/jimmunol.144.5.1705

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In vivo persistence of donor cells following adoptive transfer of allogeneic dendritic cells in HIV-infected patients

Autor: M H, Shapero, S K, Kundu, E, Engleman, R, Laus, W C, van Schooten, T C, Merigan

Publikováno v: Cell transplantation. 9(3)

Peripheral blood samples from HIV-seropositive individuals enrolled in a pilot clinical trial investigating the use of allogeneic dendritic cell therapy were evaluated for mixed chimerism. In this study, dendritic cells from HLA-identical, HIV-serone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::759e4fabe9f9cc9dd42308995bc4dc9a
https://pubmed.ncbi.nlm.nih.gov/10972330

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A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS

Autor: J D, Baxter, D L, Mayers, D N, Wentworth, J D, Neaton, M L, Hoover, M A, Winters, S B, Mannheimer, M A, Thompson, D I, Abrams, B J, Brizz, J P, Ioannidis, T C, Merigan

Publikováno v: AIDS (London, England). 14(9)

To determine the short-term effects of using genotypic antiretroviral resistance testing (GART) with expert advice in the management of patients failing on a protease inhibitor and two nucleoside reverse transcriptase inhibitors.Prospective randomize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbd9d9d9e01b70ac863d95a121972a39
https://pubmed.ncbi.nlm.nih.gov/10894268

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Frequency of antiretroviral drug resistance mutations in HIV-1 strains from patients failing triple drug regimens. The Terry Beirn Community Programs for Clinical Research on AIDS

Autor: M A, Winters, J D, Baxter, D L, Mayers, D N, Wentworth, M L, Hoover, J D, Neaton, T C, Merigan

Publikováno v: Antiviral therapy. 5(1)

The frequency of protease and reverse transcriptase (RT) gene mutations was determined in HIV-1 strains from 153 patients entering the CPCRA 046 (GART) study who were failing triple-drug regimens consisting of one protease inhibitor (PI) and two RT i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14f6c24d5a8c1e93afbf575507cbb023
https://pubmed.ncbi.nlm.nih.gov/10846594

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Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART)

Autor: C M, Gray, J, Lawrence, J M, Schapiro, J D, Altman, M A, Winters, M, Crompton, M, Loi, S K, Kundu, M M, Davis, T C, Merigan

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(3)

Peptide/MHC tetrameric complexes were used to enumerate the frequency of HLA class I-restricted epitope-specific CD8+ T cells in 18 HLA-A*0201 HIV type 1-infected asymptomatic patients. HLA-A*0201 molecules were complexed to HIV Gag p17 (amino acids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bfdce98d2f291f58960317f69e770583
https://pubmed.ncbi.nlm.nih.gov/9973442

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