Zobrazeno 1 - 10
of 242
pro vyhledávání: '"T. Bruder"'
Autor:
T. Bruder-Nascimento, S. Cordellini
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 44, Iss 4, Pp 337-344 (2011)
Androgenic anabolic steroid, physical exercise and stress induce cardiovascular adaptations including increased endothelial function. The present study investigated the effects of these conditions alone and in combination on the vascular responses of
Externí odkaz:
https://doaj.org/article/cab44b3442b54c0587422281ee4624e5
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 330-343 (2023)
Impairment of GABAergic inhibitory neuronal function is linked to epilepsy and other neurological and psychiatric disorders. Recombinant adeno-associated virus (rAAV)-based gene therapy targeting GABAergic neurons is a promising treatment for GABA-as
Externí odkaz:
https://doaj.org/article/633f6c85c70a407c989042e89a913a96
Autor:
Bradley S. Hollidge, Hayley B. Carroll, Randolph Qian, Madison L. Fuller, April R. Giles, Andrew C. Mercer, Olivier Danos, Ye Liu, Joseph T. Bruder, Jared B. Smith
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare t
Externí odkaz:
https://doaj.org/article/211584121410446c9ae0775d23eb5024
Autor:
Alexander W.M. Hooper, Hayes Wong, Yosuke Niibori, Rozita Abdoli, Subha Karumuthil-Melethil, Chunping Qiao, Olivier Danos, Joseph T. Bruder, David R. Hampson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 196-209 (2021)
Fragile X syndrome (FXS), a neurodevelopmental disorder with no known cure, is caused by a lack of expression of the fragile X mental retardation protein (FMRP). As a single-gene disorder, FXS is an excellent candidate for viral-vector-based gene the
Externí odkaz:
https://doaj.org/article/39f2762e4bc2409e975a474aed179042
Autor:
Hayes Wong, Alexander W.M. Hooper, Yosuke Niibori, Shiron J. Lee, Luca A. Hategan, Liang Zhang, Subha Karumuthil-Melethil, Sally M. Till, Peter C. Kind, Olivier Danos, Joseph T. Bruder, David R. Hampson
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105118- (2020)
Fragile X syndrome (FXS), a neurodevelopmental disorder with autistic features, is caused by the loss of the fragile X mental retardation protein. Sex-specific differences in the clinical profile have been observed in FXS patients, but few studies ha
Externí odkaz:
https://doaj.org/article/408689585b4c4ab0b7a92f55b5b78196
Autor:
Matthew Piechnik, Paige C. Amendum, Kazuki Sawamoto, Molly Stapleton, Shaukat Khan, Nidhi Fnu, Victor Álvarez, Angelica Maria Herreño Pachon, Olivier Danos, Joseph T. Bruder, Subha Karumuthil-Melethil, Shunji Tomatsu
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12693
Adeno-associated virus (AAV) vector-based therapies can effectively correct some disease pathology in murine models with mucopolysaccharidoses. However, immunogenicity can limit therapeutic effect as immune responses target capsid proteins, transduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c3b2d0ff5777290423eb717e88e027
Autor:
Rozita Abdoli, Subha Karumuthil-Melethil, Yosuke Niibori, Alexander W.M. Hooper, David R. Hampson, Olivier Danos, Hayes Wong, Chunping Qiao, Joseph T. Bruder
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 196-209 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 196-209 (2021)
Fragile X syndrome (FXS), a neurodevelopmental disorder with no known cure, is caused by a lack of expression of the fragile X mental retardation protein (FMRP). As a single-gene disorder, FXS is an excellent candidate for viral-vector-based gene the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bc7c918cc34d19f59dd4201f282537
https://doi.org/10.1016/j.omtm.2021.06.013
https://doi.org/10.1016/j.omtm.2021.06.013
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Shunji Tomatsu, Kazuki Sawamoto, Molly Stapleton, Shaukat Khan, Subha Karumuthil-Melethil, Olivier Danos, Joseph T. Bruder
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 50-61 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 50-61 (2020)
Mucopolysaccharidosis type IVA (MPS IVA) is due to the deficiency of GALNS (N-acetylgalactosamine 6-sulfate sulfatase) and is characterized by systemic skeletal dysplasia. We have evaluated adeno-associated virus 8 (AAV8) vectors expressing different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56331e54e1a2d93dce38dd3a8bd8e78c
https://doi.org/10.1016/j.omtm.2020.05.015
https://doi.org/10.1016/j.omtm.2020.05.015