Zobrazeno 1 - 10
of 26
pro vyhledávání: '"T. Braakman"'
Autor:
Maarten van Reeuwijk, Sietse T. Braakman, Mean Ghim, Spencer J. Sherwin, Sung-Wook Yang, Paola Alpresa, Stephen G. Gray, Peter D. Weinberg
Publikováno v:
H973
H959
Am J Physiol Heart Circ Physiol
H959
Am J Physiol Heart Circ Physiol
Transport of macromolecules across vascular endothelium and its modification by fluid mechanical forces are important for normal tissue function and in the development of atherosclerosis. However, the routes by which macromolecules cross endothelium,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2016aa6993234f4be6d8ebfa0512d53a
https://doi.org/10.1152/ajpheart.00218.2017
https://doi.org/10.1152/ajpheart.00218.2017
Autor:
Darryl R. Overby, Enhua H. Zhou, C. Ross Ethier, Sietse T. Braakman, W. Daniel Stamer, Jeffrey J. Fredberg, Mark Johnson
Publikováno v:
Progress in Retinal and Eye Research. 44:86-98
Ocular hypertension in glaucoma develops due to age-related cellular dysfunction in the conventional outflow tract, resulting in increased resistance to aqueous humor outflow. Two cell types, trabecular meshwork (TM) and Schlemm's canal (SC) endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c24c15ed1f6a50f27639c72af9b24fd
https://doi.org/10.1016/j.preteyeres.2014.08.002
https://doi.org/10.1016/j.preteyeres.2014.08.002
Correction: Corrigendum: Biomechanics of subcellular structures by non-invasive Brillouin microscopy
Autor:
Sietse T. Braakman, Giuseppe Antonacci
Publikováno v:
Scientific Reports. 7
Scientific Reports 6: Article number: 37217; published online: 15 November 2016; updated: 09 May 2017 The authors wish to acknowledge other contributors and other sources of funding. The Author Contributions statement should read: G.A. and S.B. contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee077f09132789cdbcee399c4c957df
https://doi.org/10.1038/srep46789
https://doi.org/10.1038/srep46789
Autor:
A. Thomas Read, Ryan M. Pedrigi, James A.E. Smith, W. Daniel Stamer, Darryl R. Overby, Sietse T. Braakman, C. Ross Ethier
Publikováno v:
Experimental Eye Research. 127:224-235
The bulk of aqueous humor passing through the conventional outflow pathway must cross the inner wall endothelium of Schlemm's canal (SC), likely through micron-sized transendothelial pores. SC pore density is reduced in glaucoma, possibly contributin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a507151ae9e90de5b7fb07d1ac2cf76c
https://doi.org/10.1016/j.exer.2014.08.003
https://doi.org/10.1016/j.exer.2014.08.003
Autor:
Giuseppe Antonacci, Sietse T. Braakman
Publikováno v:
Scientific Reports.
Cellular biomechanics play a pivotal role in the pathophysiology of several diseases. Unfortunately, current methods to measure biomechanical properties are invasive and mostly limited to the surface of a cell. As a result, the mechanical behaviour o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166affeed1d4494e57efff233b6a66cc
All aqueous humor draining through the conventional outflow pathway must cross the endothelium of Schlemm's canal (SC), likely by passing through micron-sized transendothelial pores. SC pores are non-uniformly distributed along the inner wall endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2259566e856a396b99d548a351835f47
http://hdl.handle.net/10044/1/19251
http://hdl.handle.net/10044/1/19251
Autor:
Darryl R, Overby, Enhua H, Zhou, Rocio, Vargas-Pinto, Ryan M, Pedrigi, Rudolf, Fuchshofer, Sietse T, Braakman, Ritika, Gupta, Kristin M, Perkumas, Joseph M, Sherwood, Amir, Vahabikashi, Quynh, Dang, Jae Hun, Kim, C Ross, Ethier, W Daniel, Stamer, Jeffrey J, Fredberg, Mark, Johnson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(38)
Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not known. We tested the hypothesis that altered biomechanical behavior of Schlemm's canal (SC) ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df81091ad1329c5d30022133e57ad136
https://pubmed.ncbi.nlm.nih.gov/25201985
https://pubmed.ncbi.nlm.nih.gov/25201985
Autor:
S. J. H. Van Deventer, Daniel H. Present, Bruce E. Sands, Daniel K. Podolsky, Paul Rutgeerts, Stephan R. Targan, Th.F. Schaible, T. Braakman, Lloyd Mayer, R. A. van Hogezand, Stephen B. Hanauer, K. L. Dewoody
Publikováno v:
The New England journal of medicine, 340, 1398-1405. Massachussetts Medical Society
New England journal of medicine, 340(18), 1398-1405. Massachussetts Medical Society
New England journal of medicine, 340(18), 1398-1405. Massachussetts Medical Society
Background Enterocutaneous fistulas are a serious complication of Crohn's disease and are difficult to treat. Infliximab, a chimeric monoclonal antibody to tumor necrosis factor alpha, has recently been developed as a treatment for Crohn's disease. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ebdb0980b5b78beddf7620384d5593
https://dare.uva.nl/personal/pure/en/publications/infliximab-for-the-treatment-of-fistulas-in-patients-with-crohns-disease(a106b22a-103b-4afc-adf9-64798bf0a278).html
https://dare.uva.nl/personal/pure/en/publications/infliximab-for-the-treatment-of-fistulas-in-patients-with-crohns-disease(a106b22a-103b-4afc-adf9-64798bf0a278).html
Autor:
S. J. H. Van Deventer, Paul Rutgeerts, C Kothe, Karel Geboes, R. A. van Hogezand, F Baert, DM Chalmers, T. F. Schaible, Geert D'Haens, T. Braakman
Publikováno v:
Gastroenterology, 116(5), 1029-1034. W.B. Saunders Ltd
Background & Aims: Tumor necrosis factor (TNF) is a pivotal cytokine in intestinal inflammation. Controlled trials using a chimeric anti-TNF antibody (infliximab) have shown its efficacy in refractory Crohn's disease. Methods: Endoscopic and histolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84990064c3c03435f4fcb979c15bad15
https://doi.org/10.1016/s0016-5085(99)70005-3
https://doi.org/10.1016/s0016-5085(99)70005-3
Autor:
K. L. Dewoody, T. F. Schaible, Stephan R. Targan, S. J. H. Van Deventer, T. Braakman, Stephen B. Hanauer, Paul Rutgeerts, Daniel H. Present, Lloyd Mayer
Publikováno v:
The New England journal of medicine, 337, 1029-1035. Massachussetts Medical Society
Background Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor alpha, specifically chimeric monoclonal antibody cA2, in the treatment of Crohn's disease. Methods We conducted a 12-week multicenter,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37d1fc27af96e76e0059277982b305f
https://doi.org/10.1056/nejm199710093371502
https://doi.org/10.1056/nejm199710093371502