Curcumin induced oxidative stress attenuation by N-acetylcysteine co-treatment: a fibroblast and epithelial cell in-vitro study in idiopathic pulmonary fibrosis

Autor: L. R. Rodriguez, S. N. Bui, R. T. Beuschel, E. Ellis, E. M. Liberti, M. K. Chhina, B. Cannon, M. Lemma, S. D. Nathan, G. M. Grant

Publikováno v: Molecular Medicine, Vol 25, Iss 1, Pp 1-12 (2019)

Abstract Background Idiopathic Pulmonary Fibrosis (IPF) is a fatal lung disease of unknown etiology with only two federally approved drug options. Given the complex molecular pathogenesis of IPF involving multiple cell types and multiple pathways, we

Externí odkaz: https://doaj.org/article/ea796480e119472e82dd264c11f4be2c

IBEX: A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Autor: Anita Gola, Li Yao, Joshua Croteau, Rebecca T. Beuschel, Rochelle M. Shih, Colin J Chu, Juraj Kabat, Nishant Thakur, Andrea J. Radtke, Ronald N. Germain, Jonathan M. Hernandez, Bradley C. Lowekamp, Evelyn Kandov, Jeremy L. Davis, Ziv Yaniv, Emily Speranza

Publikováno v: Proc Natl Acad Sci U S A
Radtke, A J, Kandov, E, Lowekamp, B, Speranza, E, Chu, C J, Gola, A, Thakur, N, Shih, R, Yao, L, Yaniv, Z R, Beuschel, R T, Kabat, J, Croteau, J, Davis, J, Hernandez, J M & Germain, R N 2020, ' IBEX : A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 52, pp. 33455-33465 . https://doi.org/10.1073/pnas.2018488117

The diverse composition of mammalian tissues poses challenges for understanding the cell-cell interactions required for organ homeostasis and how spatial relationships are perturbed during disease. Existing methods such as single-cell genomics, lacki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0666e9c8d6dfd405da5ddb973c146f0
https://doi.org/10.1073/pnas.2018488117

Anatomical Structures, Cell Types, and Biomarkers Tables Plus 3D Reference Organs in Support of a Human Reference Atlas

Autor: Sun X, Muzlifah Haniffa, Valerius Mt, Jacqueline Ho, Yongqun He, Sunshine J, Rebecca T. Beuschel, Avinash Boppana, Laura Jardine, James C. Gee, Sarah A. Teichmann, Fiona Ginty, Teri A. Longacre, S. Lee, Marda Jorgensen, Yangyang Lin, Bernard A, Shin Lin, Andrea J. Radtke, David Osumi-Sutherland, Jeremy A. Miller, Andreas Bueckle, Rajeev Malhotra, Ellen M. Quardokus, John W. Hickey, Griffin M. Weber, Maigan A. Brusko, Marc K. Halushka, Katy Börner, Gloria S. Pryhuber, Paul H, Clive Wasserfall, Bruce Herr, Songlin Ding, Kristen Browne, Sanjay Jain

Publikováno v: Nat Cell Biol

1.AbstractThis paper reviews efforts across 16 international consortia to construct human anatomical structures, cell types, and biomarkers (ASCT+B) tables and three-dimensional reference organs in support of a Human Reference Atlas. We detail the on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c6fc5a9bec028cbf953fafa06d43eb
https://europepmc.org/articles/PMC10079270/

IBEX – A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Autor: Bradley C. Lowekamp, Anita Gola, Jonathan M. Hernandez, Colin J Chu, Jeremy L. Davis, Rebecca T. Beuschel, Joshua Croteau, Rochelle M. Shih, Evelyn Kandov, Ronald N. Germain, Ziv Yaniv, Emily Speranza, Juraj Kabat, Nishant Thakur, Andrea J. Radtke, Li Yao

The diverse composition of mammalian tissues poses challenges for understanding the cell-cell interactions required for organ homeostasis and how spatial relationships are perturbed during disease. Existing methods such as single-cell genomics, lacki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06665875c0e5026e315e46b11972f37d
https://doi.org/10.1101/2020.11.20.390690

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