Zobrazeno 1 - 10
of 50
pro vyhledávání: '"T. B. Adams"'
Autor:
Alan M. Jeffrey, Sean V. Taylor, T. B. Adams, Wasma Alhusainy, Michael J. Iatropoulos, Gary M. Williams, Ivonne M.C.M. Rietjens
Publikováno v:
Food and Chemical Toxicology. 74:28-34
The alkenylbenzene methyleugenol occurs naturally in a variety of spices and herbs, including basil, and their essential oils. At high dose levels methyleugenol induces hepatocarcinogenicity in rodents following bioactivation to 1'-sulfooxymethyleuge
Autor:
Maria Bastaki, M. M. McGowen, Ivonne M.C.M. Rietjens, Lawrence J. Marnett, Robert L. Smith, Samuel M. Cohen, Stephen S. Hecht, Nigel J. Gooderham, Sean V. Taylor, Shoji Fukushima, Christie L. Harman, T. B. Adams
Publikováno v:
Journal of Food Science. 79:R428-R441
This publication is the 1st in a series of publications by the Expert Panel of the Flavor and Extract Manufacturers Assoc. summarizing the Panel's 3rd re-evaluation of Generally Recognized as Safe (GRAS) status referred to as the GRASr2 program. In 2
Autor:
Stephen S. Hecht, Sean V. Taylor, Robert L. Smith, Maria Bastaki, Shoji Fukushima, Nigel J. Gooderham, Lawrence J. Marnett, C. G. Harman, Samuel M. Cohen, T. B. Adams, Ivonne M.C.M. Rietjens
Publikováno v:
Chemical Research in Toxicology, 27(7), 1092-1103
Chemical Research in Toxicology 27 (2014) 7
Chemical Research in Toxicology 27 (2014) 7
The metabolic fate of a compound is determined by numerous factors including its chemical structure. Although the metabolic options for a variety of functional groups are well understood and can often provide a rationale for the comparison of toxicit
Autor:
Gabriele Scholz, T. B. Adams, Alicia Paini, Ivonne M.C.M. Rietjens, Sean V. Taylor, Wasma Alhusainy, Benoît Schilter, Johannes H.J. van den Berg, Peter J. van Bladeren, Ans Punt
Publikováno v:
Molecular Nutrition & Food Research, 57(11), 1969-1978
Molecular Nutrition & Food Research 57 (2013) 11
Molecular Nutrition & Food Research 57 (2013) 11
ScopeThe present work investigates whether the previous observation that the basil flavonoid nevadensin is able to inhibit sulfotransferase (SULT)-mediated estragole DNA adduct formation in primary rat hepatocytes could be validated in vivo. Methods
Autor:
Peter J. van Bladeren, Ans Punt, Suzanne J. P. L. van den Berg, Mariska Asselman, T. B. Adams, Alicia Paini, Ivonne M.C.M. Rietjens, Wasma Alhusainy, Gabriele Scholz, A. Spenkelink, Adelaine Campana, Benoît Schilter
Publikováno v:
Toxicological sciences 129 (2012) 1
Toxicological sciences, 129(1), 174-187
Toxicological sciences, 129(1), 174-187
The alkenylbenzene estragole is a constituent of several herbs and spices. It induces hepatomas in rodents at high doses following bioactivation by cytochrome P450s and sulfotransferases (SULTs) giving rise to the ultimate carcinogenic metabolite 1'-
Autor:
Ans Punt, Jochem Louisse, Wasma Alhusainy, P.J. van Bladeren, T. B. Adams, Ivonne M.C.M. Rietjens, Alicia Paini, Gabriele Scholz, A. Spenkelink, Benoît Schilter, Thierry Delatour, J.J.M. Vervoort
Publikováno v:
Toxicology and Applied Pharmacology 245 (2010) 2
Toxicology and Applied Pharmacology, 245(2), 179-190
Toxicology and Applied Pharmacology, 245(2), 179-190
Estragole is a natural constituent of several herbs and spices including sweet basil. In rodent bioassays, estragole induces hepatomas, an effect ascribed to estragole bioactivation to 1'-sulfooxyestragole resulting in DNA adduct formation. The prese
Autor:
T. B. Adams, Finlay D. Morrison, Robert M. Bowman, Gustau Catalan, M. M. Saad, J. M. Gregg, A. Schilling, P. Baxter, James F. Scott
Publikováno v:
Integrated Ferroelectrics. 92:53-64
This paper summarises some of the most recent work that has been done on nanoscale ferroelectrics as a result of a joint collaborative research effort involving groups in Queen's University Belfast, the University of Cambridge and the University of S
Autor:
Finlay D. Morrison, A. Schilling, P. Baxter, M. M. Saad, J. M. Gregg, T. B. Adams, X. H. Zhu, Pavlo Zubko, Robert M. Bowman, James F. Scott
Publikováno v:
Journal de Physique IV (Proceedings). 128:63-70
The focused ion beam microscope has been used to make thin lamellae and nanoscale washers from single crystals of BaTiO3. The thin lamellae were used as the dielectric layers in ‘thin film’ capacitor heterostructures, and investigated for their f
Autor:
Jay I. Goodman, Philip S. Portoghese, Samuel M. Cohen, William J. Waddell, Robert L. Smith, T. B. Adams, Victor J. Feron, John Doull, Lawrence J. Marnett, I. C. Munro, Bernard M. Wagner
Publikováno v:
Food and Chemical Toxicology. 43:1207-1240
This publication is the eighth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the panel initiated a comprehensive program to re-evaluate the safety of more than 170
Autor:
Samuel M. Cohen, Victor J. Feron, T. B. Adams, Robert L. Smith, Bernard M. Wagner, Jay I. Goodman, Philip S. Portoghese, William J. Waddell, I. C. Munro, John Doull, Lawrence J. Marnett
Publikováno v:
Food and Chemical Toxicology. 43:1141-1177
The current status of the GRAS evaluation program of flavoring substances operated by the Expert Panel of FEMA is discussed. The Panel maintains a rigorous rotating 10-year program of continuous review of scientific data related to the safety evaluat