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pro vyhledávání: '"T. Arvinte"'
Akademický článek
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Akademický článek
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Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 78(1-3)
Transforming growth factor betas (TGF-betas) play critical roles in many diseased states and injury repair processes. Exogenous delivery of TGF-beta may thus have therapeutic applications. Here, crystals of TGF-beta3 (TGF-beta3) are being evaluated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e63e1ed938025798186d28ca2b1b90
https://pubmed.ncbi.nlm.nih.gov/11772446
https://pubmed.ncbi.nlm.nih.gov/11772446
Publikováno v:
Journal of molecular biology. 310(1)
Lyophilization is frequently used to increase the shelf-life of biopharmaceuticals containing antibodies. A case in which an anti-idiotypic antibody, MMA 383, substantially lost its in vivo immunogenic properties although the protein was not degraded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62dd6d7140491086961dbafea4992feb
https://pubmed.ncbi.nlm.nih.gov/11419944
https://pubmed.ncbi.nlm.nih.gov/11419944
Publikováno v:
Journal of biomolecular NMR. 16(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::091ac6a0e49ab587638fe4770d3388fd
https://pubmed.ncbi.nlm.nih.gov/10723998
https://pubmed.ncbi.nlm.nih.gov/10723998
Publikováno v:
Pharmaceutical research. 16(10)
The formation of succinimide intermediates at Asp-Gly sites and their hydrolysis products, e.g., isoAsp isomers, represents a common source of microheterogeneity in therapeutic proteins. Here we report on the stabilization effect of a zinc chloride i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cfd856ca240ca669f8ff65023bafcc2
https://pubmed.ncbi.nlm.nih.gov/10554108
https://pubmed.ncbi.nlm.nih.gov/10554108
Publikováno v:
Journal of molecular biology. 285(1)
Late-onset diabetes is typically associated with amyloid deposits of fibrillar amylin in the pancreatic islets. Aqueous synthetic human amylin spontaneously forms polymorphic fibrils in vitro, and this system was used to examine the dynamics of fibri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba30eb9fccfacc9c9e87a675b18ed139
https://pubmed.ncbi.nlm.nih.gov/9878384
https://pubmed.ncbi.nlm.nih.gov/9878384
Publikováno v:
Pharmaceutical research. 15(9)
To gain information on the chemical stability pattern and the kinetics of the degradation of recombinant hirudin variant HV1 (rHir), a thrombin-specific inhibitor protein of 65 amino acids, in aqueous solution as a function of pH.Stability of rHir wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ea2814bc94f240c50db78089d398983
https://pubmed.ncbi.nlm.nih.gov/9755900
https://pubmed.ncbi.nlm.nih.gov/9755900
Autor:
T, Arvinte, A F, Drake
Publikováno v:
The Journal of biological chemistry. 268(9)
Molecular conformations of salmon (sCT) and human (hCT) calcitonin in media with different concentrations of methanol/water and trifluoroethanol/water have been investigated by fluorescence, circular dichroism (CD) and infrared spectroscopy technique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b38bf7da45ae48dbe55acba03b5e7a83
https://pubmed.ncbi.nlm.nih.gov/8454613
https://pubmed.ncbi.nlm.nih.gov/8454613
Publikováno v:
The Journal of biological chemistry. 268(9)
Turbidity measurements of the kinetics of human calcitonin (hCT) fibrillation showed a linear dependence of the logarithm of fibrillation time (the time the sample is not fibrillated) and the logarithm of hCT concentration. This ln/ln plot linearity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be8a46c9a2c1e66c7b5dc18e257257ba
https://pubmed.ncbi.nlm.nih.gov/8454614
https://pubmed.ncbi.nlm.nih.gov/8454614