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Akademický článek

Synthesis and characterization of novel imidazoquinoline based 2-azetidinones as potent antimicrobial and anticancer agents

Autor: Reshma Kayarmar, G.K. Nagaraja, Prashantha Naik, H. Manjunatha, B.C. Revanasiddappa, T. Arulmoli

Publikováno v: Journal of Saudi Chemical Society, Vol 21, Iss S1, Pp S434-S444 (2017)

A new series of N-substituted azetidinones (9a–h) synthesized by condensation of 4-arylidene hydrazino 1-isobutyl-1H-imidazo[4,5-c]quinolines (8a–h) with chloroacetyl chloride afforded 4-arylazetidin-2-ones (9a–h). The synthesized compounds wer

Externí odkaz: https://doaj.org/article/d3664b433b8d4851abd340a5f18eb26a

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Akademický článek

1-[2-(4-Chlorophenyl)-5-phenyl-2,3-dihydro-1,3,4-oxadiazol-3-yl]ethanone

Autor: Hoong-Kun Fun, Suhana Arshad, P. C. Shyma, Balakrishna Kalluraya, T. Arulmoli

Publikováno v: Acta Crystallographica Section E, Vol 68, Iss 6, Pp o1901-o1901 (2012)

In the title compound, C16H14ClN3O2, the 2,3-dihydro-1,3,4-oxadiazole ring [maximum deviation = 0.030 (1) Å] and the pyridine ring [maximum deviation = 0.012 (1) Å] are inclined slightly to one another, making a dihedral angle of 11.91 (5)°. The c

Externí odkaz: https://doaj.org/article/2210c1dfb09242b8b1250880d6fd3d13

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Akademický článek

2-(4-Chloroanilino)-1-(4-chlorophenyl)ethanone

Autor: Hoong-Kun Fun, Ching Kheng Quah, A. M. Vijesh, A. M. Isloor, T. Arulmoli

Publikováno v: Acta Crystallographica Section E, Vol 67, Iss 12, Pp o3373-o3373 (2011)

In the title compound, C14H11Cl2NO, the benzene rings form a dihedral angle of 3.14 (6)°. Overall, the molecule is close to being planar (r.m.s. deviation for all the non-H atoms = 0.054 Å). No significant directional intermolecular interactions ar

Externí odkaz: https://doaj.org/article/38a7e0ea97b64af5a33657e913985014

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Akademický článek

2-(4-Chlorophenyl)-2-oxoethyl 3,4-dimethoxybenzoate

Autor: Hoong-Kun Fun, Ching Kheng Quah, A. M. Vijesh, A. M. Isloor, T. Arulmoli

Publikováno v: Acta Crystallographica Section E, Vol 67, Iss 12, Pp o3351-o3351 (2011)

In the title compound, C17H15ClO5, the benzene rings forms a dihedral angle of 74.45 (10)°. In the crystal, molecules are linked into C(13) chains along [011] via C—H...O hydrogen bonds. The crystal packing also features short Cl...Cl contacts of

Externí odkaz: https://doaj.org/article/c26797f77a8f435c8dceec1bd1a25d85

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Akademický článek

Diethyl 4-[5-(biphenyl-4-yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate ethanol monosolvate

Autor: Hoong-Kun Fun, Madhukar Hemamalini, A. M. Vijesh, Arun M. Isloor, T. Arulmoli

Publikováno v: Acta Crystallographica Section E, Vol 67, Iss 7, Pp o1768-o1769 (2011)

In the title compound, C28H29N3O4·C2H6O, the benzene ring makes dihedral angles of 33.72 (13) and 32.86 (13)°, respectively, with the adjacent pyrazole and phenyl rings. In the crystal, the components are connected via intermolecular N—H...O, N�

Externí odkaz: https://doaj.org/article/327816114ea64a76b4ca6c509d3f7482

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Synthesis of azabicyclo[4.2.0]octa-1,3,5-trien-8-one analogues of 1H-imidazo[4,5-c]quinoline and evaluation of their antimicrobial and anticancer activities

Autor: Prashantha Naik, Reshma Kayarmar, K. P. Rajesh, Suchetha Shetty, Manjunath Bhat, T. Arulmoli, Gundibasappa Karikannar Nagaraja

Publikováno v: Medicinal Chemistry Research. 23:2964-2975

In search of new and efficient antimicrobial and anticancer agents based on the imidazoquinoline structural framework, a series of novel 7-(1-isobutyl-1H-imidazo[4,5-c]quinolin-4-yl)-7-azabicyclo[4.2.0]octa-1,3,5-trien-8-ones (8a–f) were synthesize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d85b311ef06faec4c3acc319af59623
https://doi.org/10.1007/s00044-013-0885-9

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Synthesis and biological evaluation of some Schiff bases of 4-amino-5-(4-methylsulfonyl)benzyl-2,4-dihydro-3H-[1,2,4]-triazole-3-thione

Autor: Boja Poojary, V. Sumangala, N. Chidananda, T. Arulmoli, Shalini Shenoy

Publikováno v: Medicinal Chemistry Research. 22:2921-2928

The basic nucleus 4-amino-5-[4-(methylsulfonyl)benzyl]-2,4-dihydro-3H-[1,2,4]-triazole-3-thione was prepared by cyclisation of potassium dithiocarbazinate with hydrazine hydrate using ethanol as solvent under reflux condition. The compound which has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9a4460d8939f3a8e46e0fda0b1a8d04
https://doi.org/10.1007/s00044-012-0294-5

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