Zobrazeno 1 - 10
of 29
pro vyhledávání: '"T. Andrew Mitchell"'
Autor:
Sarita Singh, Jacob P. Grabowski, Shilpa Pohani, C. Fiore Apuzzo, David C. Platt, Marjorie A. Jones, T. Andrew Mitchell
Publikováno v:
Molecules, Vol 25, Iss 22, p 5461 (2020)
Construction of a focused library of polycyclic ether-benzopyrans was undertaken in order to discover new therapeutic compounds that affect Leishmania growth and infectivity. This is especially of interest since there are few drug therapies for leish
Externí odkaz:
https://doaj.org/article/8bc3ca7971904e0db3edcafb773f4877
Autor:
Adam J. Youman, Samantha N. Rokey, Jacob P. Grabowski, Wentao Guo, Qing Sun, Susanna N. Angles, John R. Goodell, Dean J. Tantillo, T. Andrew Mitchell
Publikováno v:
The Journal of Organic Chemistry. 88:5972-5981
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::168e13c2c06bc168a9ba7190d8d42ee9
https://doi.org/10.1021/acs.joc.3c00318
https://doi.org/10.1021/acs.joc.3c00318
Autor:
Seth I. Corrie, Aaron C. Pearce, Jacob P. Grabowski, Kee A. Randolph, Wentao Guo, Dean J. Tantillo, T. Andrew Mitchell
Publikováno v:
Tetrahedron Letters. 107:154094
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9787e0a305aa9376877d8129f3411fd7
https://doi.org/10.1016/j.tetlet.2022.154094
https://doi.org/10.1016/j.tetlet.2022.154094
Autor:
T. Andrew Mitchell, Marjorie A. Jones, David C. Platt, C. Fiore Apuzzo, Shilpa Pohani, Sarita Singh, Jacob P. Grabowski
Publikováno v:
Molecules
Volume 25
Issue 22
Molecules, Vol 25, Iss 5461, p 5461 (2020)
Volume 25
Issue 22
Molecules, Vol 25, Iss 5461, p 5461 (2020)
Construction of a focused library of polycyclic ether-benzopyrans was undertaken in order to discover new therapeutic compounds that affect Leishmania growth and infectivity. This is especially of interest since there are few drug therapies for leish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5713b59a1282c9ae133d97839c9fb8
Autor:
Paul Wendelboe, Erica L. Woodall, Chunyin M. Law, Christian R. Zwick, Riley H. Kaufman, John R. Goodell, T. Andrew Mitchell, Christopher G. Hamaker, Justin A. Simanis, Henry B. Wedler, Dean J. Tantillo
Publikováno v:
The Journal of Organic Chemistry. 83:9818-9838
Oxidopyrylium-alkene [5 + 2] cycloaddition conjugate addition cascade (C3) sequences are described. Intramolecular cycloadditions involving terminal alkenes, enals, and enones were investigated. Substrates with tethers of varying lengths delivered fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b4ce3b697cadef93db16ba633b75d6
https://doi.org/10.1021/acs.joc.8b01322
https://doi.org/10.1021/acs.joc.8b01322
Autor:
Chunyin M. Law, T. Andrew Mitchell, Jacob J. Bulandr, Jacob P. Grabowski, John R. Goodell, Jessica L Shaw
Publikováno v:
The Journal of organic chemistry. 84(16)
Systematic investigation of intramolecular silyloxypyrone-based [5 + 2] cycloadditions revealed three significant factors impacting conversion to cycloadduct: (1) the silyl transfer group has a substantial influence on the rate of reaction, and the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58d8672fc9fff102c7f474b5e183399
https://pubmed.ncbi.nlm.nih.gov/31322900
https://pubmed.ncbi.nlm.nih.gov/31322900
Autor:
Justin A. Simanis, Chunyin M. Law, John R. Goodell, T. Andrew Mitchell, Gregory M. Ferrence, Samantha Willens Behrends, Jacob J. Bulandr, Shilpa Pohani, Samantha N. Rokey
Publikováno v:
Tetrahedron Letters. 61:152377
Intramolecular oxidopyrylium-based [5 + 2] cycloadditions utilizing chiral auxiliaries were investigated. Both acetoxypyranones and silyloxypyrones were employed and sulfinimines, oxazolidinones, hydrazones, and chiral enamines were explored. Carbony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecf9b82d3d95e34e0b47e2ae0f3dac31
https://doi.org/10.1016/j.tetlet.2020.152377
https://doi.org/10.1016/j.tetlet.2020.152377
Publikováno v:
Tetrahedron Letters. 61:152324
Synthetic efforts toward the tricyclic core of (±)-toxicodenane A are reported. This strategy takes advantage of the Feist-Benary furan annulation, Achmatowicz oxidative rearrangement, and oxidopyrylium-based [5+2] cycloaddition to access a key tetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b78e0450c7419560e213f5322e3087
https://doi.org/10.1016/j.tetlet.2020.152324
https://doi.org/10.1016/j.tetlet.2020.152324
Autor:
Riley H, Kaufman, Chunyin M, Law, Justin A, Simanis, Erica L, Woodall, Christian R, Zwick, Henry B, Wedler, Paul, Wendelboe, Christopher G, Hamaker, John R, Goodell, Dean J, Tantillo, T Andrew, Mitchell
Publikováno v:
The Journal of organic chemistry. 83(17)
Oxidopyrylium-alkene [5 + 2] cycloaddition conjugate addition cascade (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::249db9664ab5968b0ad92d2e8d575342
https://pubmed.ncbi.nlm.nih.gov/30001484
https://pubmed.ncbi.nlm.nih.gov/30001484
Autor:
Christopher A. Olson, T. Andrew Mitchell, Gregory M. Ferrence, Sydney C. Roche, Courtnay E. Shaner
Publikováno v:
Synthesis. 47:2756-2766
Initial synthetic efforts toward muironolide A based upon an intramolecular Diels–Alder strategy were hampered by a conjugate reduction rather than the desired half-reduction. An intermolecular Diels–Alder strategy was initiated that utilized ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd23d19846c332d07832d3ba863721b
https://doi.org/10.1055/s-0034-1380221
https://doi.org/10.1055/s-0034-1380221