Zobrazeno 1 - 10
of 241
pro vyhledávání: '"T. Aherne"'
Publikováno v:
Vascular & Endovascular Surgery; Nov2024, Vol. 58 Issue 8, p805-812, 8p
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 65:e93
Autor:
Fiona O'Neill, Martin Clynes, Finbarr O'Sullivan, Karina Horgan, Michael Henry, Joanne Keenan, Padraig Doolan, Paula Meleady, Richard Murphy, Niall Barron, Sinead T Aherne, Laura Breen, Colin Clarke
Publikováno v:
World Journal of Gastroenterology
AIM To identify miRNA-regulated proteins differentially expressed between Caco2 and HT-29: two principal cell line models of the intestine. METHODS Exponentially growing Caco-2 and HT-29 cells were harvested and prepared for mRNA, miRNA and proteomic
Matrix metalloproteinase processing of PTHrP yields a selective regulator of osteogenesis, PTHrP1–17
Autor:
G Shay, Conor C. Lynch, M Budzevich, Jeremy S. Frieling, V Izumi, S T Aherne, R G Saul, John M. Koomen
Publikováno v:
Oncogene. 36:4498-4507
Parathyroid hormone-related protein (PTHrP) is a critical regulator of bone resorption and augments osteolysis in skeletal malignancies. Here we report that the mature PTHrP1-36 hormone is processed by matrix metalloproteinases to yield a stable prod
Publikováno v:
Cancer Research. 75:P4-07
HER2 positive breast cancer accounts for approximately 20-25 % of breast cancers. Trastuzumab, a humanised monoclonal antibody, is approved for the treatment of HER2 positive breast cancer. However, the majority of metastatic HER2 positive breast can
Akademický článek
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Autor:
Maria Prencipe, Martin Clynes, Amanda O'Neill, Dara Lundon, R.W. Watson, Elaine W. Kay, G. Hurley, Sinead T Aherne, John M. Fitzpatrick, A. Boland, Colm Morrissey, Padraig Doolan, Stephen F. Madden
Publikováno v:
BMC Cancer
Background Docetaxel based therapy is one of the first line chemotherapeutic agents for the treatment of metastatic castrate-resistant prostate cancer. However, one of the major obstacles in the treatment of these patients is docetaxel-resistance. De
Autor:
Colin Clarke, Laura Breen, Mark Leonard, Niall Barron, Sinead T Aherne, Paula Kinsella, Paula Meleady, Padraig Doolan, Martin Clynes, Lin Zhang
Publikováno v:
Journal of Biotechnology. 166:105-113
The selection of clones displaying a high rate of cell growth is an essential component of Chinese hamster ovary (CHO) cell line development. In recent years various "omics" technologies have been utilised to understand the mechanisms underlying biop
Autor:
Sinéad T, Aherne, Nga T, Lao
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1509
There are a numerous target prediction algorithms that allow users to identify putative targets of their microRNAs (miRNAs) of interest. Although these tools are useful to gain insight into the potential role of miRNAs in regulating cellular processe
Autor:
Sinead T Aherne, Nga T. Lao
Publikováno v:
Methods in Molecular Biology ISBN: 9781493965229
There are a numerous target prediction algorithms that allow users to identify putative targets of their microRNAs (miRNAs) of interest. Although these tools are useful to gain insight into the potential role of miRNAs in regulating cellular processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d117de75011b9ccf5e0b006857f58ec
https://doi.org/10.1007/978-1-4939-6524-3_14
https://doi.org/10.1007/978-1-4939-6524-3_14