Zobrazeno 1 - 10 of 230 pro vyhledávání: '"T. A. Waldmann"'
1
Simultaneous Effect of Salt Creep and Dissolution in Caliper Prediction During Drilling Operations
Autor: Amílcar Martins, Rosana F. T. Lomba, Gustavo Camargo Longhin, A. A. T. A. Waldmann, B. F. da Silva
Publikováno v: Day 1 Tue, October 24, 2017.
The Brazilian pre-salt operation presents many technological challenges. Among the key aspects for a successful operation, the choice of drilling fluid is important to avoid structural problems and predict the final well caliper. Drilling operation s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b625812ba1e48046b9dab280430b92f
https://doi.org/10.4043/28006-ms
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2
T-cell receptors for cytokines: Targets for immunotherapy of leukemia/lymphoma
Autor: T. A. Waldmann
Publikováno v: Annals of Oncology. 11:S101-S106
Summary Background: Cytokine receptors are exceptionally valuable targets for immunotherapy. For example, the high affinity IL-2 receptor is expressed by abnormal T cells in patients with certain lymphoid malignancies or autoimmune disorders and in i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7a21337ced0479c6421228cbff45e5a
https://doi.org/10.1093/annonc/11.suppl_1.s101
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3
Responses in Refractory Hairy Cell Leukemia to a Recombinant Immunotoxin
Autor: T. A. Waldmann, David Robbins, Inger Margulies, Robert J. Kreitman, Wyndham H. Wilson, Maryalice Stetler-Stevenson, Ira Pastan
Publikováno v: Blood. 94:3340-3348
We report major responses in 4 of 4 patients with hairy cell leukemia (HCL) who have recently been treated on a phase I trial with the recombinant immunotoxin LMB-2. The immunotoxin, designed to target CD25+ malignancies, is composed of the Fv portio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41004c90a56149ed415343e7a20f7dd8
https://doi.org/10.1182/blood.v94.10.3340.422k19_3340_3348
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6
Recent progress in B- and T-cell lymphomas
Autor: Robert Peter Gale, T. A. Waldmann, James O. Armitage, Franco Cavalli
Publikováno v: Annals of Oncology. 5:689-696
The data we review indicate substantial progress in understanding of the biology of T- and B-cell lymphomas in humans. They indicate how processes central to normal development of B- and T-cells are corrupted in lymphomas and how these abnormalities
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebbcc1dc2363af5fd3479555e3caac7a
https://doi.org/10.1093/oxfordjournals.annonc.a058970
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7
T-cell receptor gene rearrangement in T-cell large granular leukocyte leukemia: preferential V alpha but diverse J alpha usage in one of five patients
Autor: C, Kasten-Sportès, S, Zaknoen, R G, Steis, W C, Chan, E F, Winton, T A, Waldmann
Publikováno v: Blood. 83:767-775
T-gamma lymphoproliferative disease (T-gamma LPD) is a chronic disorder of mature T cells that is associated with neutropenia and autoimmune phenomena. Although the progression of the lymphoproliferation is indolent, it is often associated with a mon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea165663c43eb3f0944da58b19576a52
https://doi.org/10.1182/blood.v83.3.767.bloodjournal833767
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8
The interleukin-2 receptor: a target for monoclonal antibody treatment of human T-cell lymphotrophic virus I-induced adult T-cell leukemia
Autor: Ivan D. Horak, Sara Zaknoen, Claude Kasten-Sportes, Richard N. Bamford, Erich Roessler, Lois E. Top, Angus Grant, T. A. Waldmann, Jeffrey D. White, Carolyn K. Goldman
Publikováno v: Blood. 82:1701-1712
Adult T-cell leukemia (ATL) is a malignancy of mature lymphocytes caused by the retrovirus human T-cell lymphotrophic virus-I (HTLV-I). It is an aggressive leukemia with an overall mortality rate of 50% within 5 months; no conventional chemotherapy r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf4b2750dd8e1e0776e440a17232bfa
https://doi.org/10.1182/blood.v82.6.1701.1701
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9
Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC
Autor: J Hakimi, V C Ha, P Lin, E Campbell, M K Gately, M Tsudo, P W Payne, T A Waldmann, A J Grant, W H Tsien
Publikováno v: The Journal of Immunology. 151:1075-1085
Mik beta 1 is a mouse mAb directed at the beta-subunit of the human IL-2R (Tac) that inhibits IL-2 binding and inhibits IL-2 induction of large granular lymphocytes (LGL). Mik beta 1 alone does not inhibit IL-2-induced T-cell proliferation, but acts
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85e4cc717588c7324b2591b92702ec69
https://doi.org/10.4049/jimmunol.151.2.1075
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10
Mik-beta 1(Fv)-PE40, a recombinant immunotoxin cytotoxic toward cells bearing the beta-chain of the IL-2 receptor
Autor: R J Kreitman, W P Schneider, C Queen, M Tsudo, D J Fitzgerald, T A Waldmann, I Pastan
Publikováno v: The Journal of Immunology. 149:2810-2815
Mik-beta 1 is a mAb that binds to the beta subunit of the IL-2R. We have constructed a recombinant single chain immunotoxin Mik-beta 1(Fv)-PE40 by genetically fusing the H and L V domains of Mik-beta 1 to each other via a peptide linker, and then to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3357d93aacf10e3a3083e04f61ef37be
https://doi.org/10.4049/jimmunol.149.8.2810
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