Zobrazeno 1 - 10 of 20 pro vyhledávání: '"T. A. Shtam"'
1
Akademický článek
EVALUATION OF EXPRESSION OF 4 MIRNAS IN CYTOLOGICAL SAMPLES AS AN ADDITIONAL METHOD OF CERVICAL CANCER DIAGNOSIS
Autor: P. A. Arkhangelskaya, R. B. Samsonov, T. A. Shtam, M. S. Knyazeva, M. K. Ivanov, S. E. Titov, N. N. Kolesnikov, E. V. Bakhidze, I. V. Berlev, A. А. Mikhetko, S. L. Vorobyev, A. V. Malek
Publikováno v: Опухоли женской репродуктивной системы, Vol 13, Iss 3, Pp 63-72 (2017)
Introduction. Cervical cancer is the 4th most common cancer among women. The main screening method for cervical cancer is cytological examination of the cervical epithelium. This method allows to evaluate the level of cervical dysplasia (malignant po
Externí odkaz: https://doaj.org/article/ff30241dd4884fb1a845af569b1177c5
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2
Akademický článek
ANALYSIS OF A MIRNA SET (MIR-21, -181A, AND -146A) AS A METHOD OF DIFFERENTIAL DIAGNOSIS OF THYROID NODULES
Autor: R. B. Samsonov, V. S. Burdakov, T. A. Shtam, Z. A. Radzhabova, Y. V. Cheburkin, D. A. Vasilyev, E. V. Tsyrlina, S. E. Titov, M. К. Ivanov, M. V. Filatov, L. M. Berstein, N. N. Kolesnikov, А. V. Malek
Publikováno v: Опухоли головы и шеи, Vol 7, Iss 2, Pp 16-24 (2017)
Introduction. In clinical practice, differential diagnosis of nodular thyroid diseases poses a serious problem which can be solved by development of new, safe, and specific thyroid tumor markers. Small regulatory RNAs (microRNA, miRNA) are a class of
Externí odkaz: https://doaj.org/article/845b68abb2c54b678a0da55371b7bead
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4
[Plasma Exosomes in Inherited Forms of Parkinson's Disease]
Autor: D G, Kulabukhova, L A, Garaeva, A K, Emelyanov, K A, Senkevich, E V, Gracheva, I V, Miliukhina, E Y, Varfolomeeva, A A, Timofeeva, A L, Schwartsman, T A, Shtam, S N, Pchelina
Publikováno v: Molekuliarnaia biologiia. 55(2)
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Alpha-synuclein misfolding and aggregation resulting in neurototoxicity is a hallmark of PD. The prion properties of alpha-synuclein are still under discussion. Exosomes (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5845626c292749e17b1167072833668c
https://pubmed.ncbi.nlm.nih.gov/33871446
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6
Aggregation by lectins as an approach for exosome isolation from biological fluids: Validation for proteomic studies
Autor: T. A. Shtam, V. Yu. Bairamukov, Stanislav N. Naryzhny, Sergey Landa, A. V. Malek, Yu. N. Orlov, Michael V. Filatov, Vladimir Burdakov
Publikováno v: Cell and Tissue Biology. 11:172-179
Exosomes, a special type of microparticles produced by cells, are currently of considerable interest for researchers. The term “exosomes” denotes extracellular vesicles of less than 120 nm in size derived from intracellular multivesicular bodies.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb05966cffe81c421083d973d19b0c2e
https://doi.org/10.1134/s1990519x17020043
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7
Histone deacetylase inhibitors cause TP53-dependent induction of p21/Waf1 in tumor cells with TP53 mutations
Autor: R. A. Kovalev, T. A. Shtam, M. V. Filatova, Andrey Volnitskiy, Evgeny M. Makarov, Vladimir Burdakov, D. V. Karelov
Publikováno v: Cell and Tissue Biology. 9:191-197
The p21/Waf1 protein is one of the main regulators of cell cycle arrest and one of the best-known transcriptional targets of the TP53 protein. Here, we demonstrated that there is activation of expression of the p21/Waf1 gene when the cells were treat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e25b21ee71451509a2b5d309d793dae
https://doi.org/10.1134/s1990519x15030086
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8
The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis
Autor: Elena Yu. Varfolomeeva, R. A. Kovalev, T. A. Shtam, Michael V. Filatov, Evgeny M. Makarov, R. A. Pantina
Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0185126 (2017)
PLoS ONE
P53 protein is more frequently mutated in human tumours compared with the other proteins. While the majority of the p53 mutations, especially within its DNA-binding domain, lead to the loss of the wild-type function, there are accumulating data demon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d053ca33986c24d74fa50ee31f316388
https://bura.brunel.ac.uk/handle/2438/16513
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9
Aberrant expression of the sox2 gene in malignant gliomas
Autor: Volnitskiĭ Av, Filatov Mv, T. A. Shtam, Semenova Ev, R. A. Kovalev
Publikováno v: Cell and Tissue Biology. 8:368-373
Both genetic and epigenetic changes underlie the mechanisms of tumor initiation and progression. In this study, we analyzed sox2 gene expression and its epigenetic changes in primary cultures of malignant gliomas. The sox2 expression was detected in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5375db47b7246d85bfc8ee7aba6b07e1
https://doi.org/10.1134/s1990519x14050101
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10
Purification and in vitro analysis of exosomes secreted by malignantly transformed human cells
Autor: S. B. Landa, Vladimir Burdakov, T. A. Shtam, Stanislav N. Naryzhny, Michael V. Filatov, T. O. Artamonova
Publikováno v: Cell and Tissue Biology. 6:317-325
Exosomes are natural nanoparticles secreted by different cells and capable of carrying protein markers and genetic information, thus participating in cellular communication. There is good reason to think that quantitative and qualitative characteriza
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1888c560d846671d826306d7d3fc9d1b
https://doi.org/10.1134/s1990519x12040116
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