Zobrazeno 1 - 8
of 8
pro vyhledávání: '"T. A. S. Amos"'
Autor:
R. J. Davidson, John M. Goldman, J. L. Lewis, S. B. Marley, Francis H. Grand, D. X. Nguyen, Myrtle Y. Gordon, T. A. S. Amos
Publikováno v:
Journal of Clinical Investigation. 102:710-715
The biological target for interferon (IFN)-alpha in chronic myeloid leukemia (CML) is unknown, but one possibility is that amplification of granulocyte-macrophage colony-forming cells (CFU-GM) is reduced. Replating CFU-GM colonies and observing secon
Autor:
M. Y. Gordon, T. A. S. Amos
Publikováno v:
STEM CELLS. 12:175-179
Stochastic effects underlie all hemopoietic cell responses but can only be observed at the level of one or a very few cells. Here we have considered the relevance of stochastic effects to aspects of hemopoietic cell development.
Publikováno v:
Leukemialymphoma. 24(1-2)
We compared bcl-2 with P-glycoprotein expression (C494 and JSB1), and both with ex vivo chemosensitivity by Differential Staining Cytotoxicity (DiSC) assay (25 cytotoxic drugs), in 76 fresh haematological specimens, including 51 chronic lymphocytic l
Publikováno v:
British journal of haematology. 92(3)
Colony formation by erythroid burst-forming units (BFU-E) involves a variable number of cell divisions before individual 'subcolonies' begin to appear. Consequently the numbers of subcolonies vary amongst individual bursts. If this observation is int
Publikováno v:
British journal of haematology. 91(2)
Inhibition of apoptosis (genetically programmed active cell death) by p210 BCR-ABL expression is a mechanism that might contribute to clonal expansion in chronic myeloid leukaemia (CML). Since cell death following exposure to ionizing radiation and m
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 40(12)
Previous cell subfractionation studies have indicated that bcl-2 is an inner mitochondrial membrane protein. We have sought to determine the ultrastructural localization of bcl-2 protein in lymphoma and breast carcinoma cell lines and biopsy material
Publikováno v:
British medical journal (Clinical research ed.). 294(6570)
Plasma glucose, insulin, and C peptide concentrations were determined after an oral glucose load in normal subjects and in a group of patients with non-insulin-dependent diabetes mellitus before and during a short course of treatment with chloroquine
Publikováno v:
Clinical Science. 74:63P-63P