Zobrazeno 1 - 10
of 162
pro vyhledávání: '"T. A. Bogush"'
Autor:
A. Lee, T. A. Bogush, A. N. Grishanina, I. P. Romanov, E. A. Bogush, S. A. Kaliuzhny, K. I. Chandran, A. M. Scherbakov, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 5-6, Pp 28-34 (2024)
Background. The cytoskeletal protein β-tubulin class III (Tubb3) is associated with tumor resistance to taxanes and vinca alkaloids, as well as with the metastatic potential of neoplasm, however, data from immunohistochemical analysis of Tubb3 expre
Externí odkaz:
https://doaj.org/article/0555cd44bacb4de28f772016a8bfef2f
Autor:
I. P. Romanov, T. A. Bogush, A. M. Scherbakov, A. A. Alimov, E. A. Bogush, A. B. Ravcheeva, A. Lee, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 1-2, Pp 29-36 (2024)
Background. Progesterone receptors (PR) are regulators of cell proliferation and therefore can be considered as an aim for targeted medications in the treatment of oncological diseases. At the same time, a quantitative assessment of PR expression in
Externí odkaz:
https://doaj.org/article/f81b3dbafd994c15b83ca033a4c0bdaf
Autor:
Yu. Yu. Shchegolev, M. A. Karpukhina, D. V. Sorokin, A. M. Scherbakov, O. E. Andreeva, V. E. Razuvaeva, T. A. Bogush, I. N. Mikhaylova, L. V. Demidov, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 50-58 (2023)
Introduction. Melanoma belongs to the group of the most malignant tumors characterized by aggressive growth and active metastasis. At the same time, the effectiveness of therapy, primarily targeted therapy, is largely limited by the rapid development
Externí odkaz:
https://doaj.org/article/94aa493afae74c17a55cd214163d9cbc
Autor:
T. A. Bogush, I. E. Mizaeva, A. A. Basharina, A. N. Grishanina, M. A. Baryshnikova, O. S. Burova, A. A. Rudakova, V. S. Kosorukov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 82-89 (2023)
Introduction. Despite advances in the treatment of melanoma, the results of therapy cannot be considered satisfactory, and the search for new drugs and effective combinations of medicine continues. The drugs are being developed aimed at reducing the
Externí odkaz:
https://doaj.org/article/e0be4c00c4b7451ab885dcd242e7fb68
Autor:
T. A. Bogush, P. D. Potselueva, A. M. Scherbakov, E. A. Bogush, A. B. Ravcheeva, N. O. Vikhlyantseva, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 3-4, Pp 39-45 (2023)
Background. Estrogen receptors beta (ERβ) are an important biological regulator and target of antiestrogens, however, unlike estrogen receptors alpha (ERɑ), their significance in the prognosis and treatment of breast cancer remains unclear. Purpose
Externí odkaz:
https://doaj.org/article/00e296c6a91b4121835632d7739bf5a6
Autor:
E. N. Kosobokova, N. A. Kalinina, M. A. Baryshnikova, V. S. Pokrovsky, O. N. Solopova, T. A. Bogush, V. S. Kosorukov
Publikováno v:
Кардиоваскулярная терапия и профилактика, Vol 22, Iss 11 (2023)
Bioresource collection of the N. N. Blokhin National Medical Research Center of Oncology is a unique structured biobank that combines different types of primary and subsidiary samples and ensures its comprehensive characterization, including both gen
Externí odkaz:
https://doaj.org/article/547d69410aa346ac9f527cf336b72004
Autor:
T. A. Bogush, S. A. Samsonik, A. A. Basharina, E. A. Bogush, O. M. Ryabinina, A. N. Grishanina, V. Yu. Kirsanov, A. V. Karpukhin, V. S. Kosorukov
Publikováno v:
Антибиотики и Химиотерапия, Vol 66, Iss 5-6, Pp 23-29 (2021)
The expression level of estrogen receptors (ERα and ERβ) in surgical tumor biopsy specimens from 167 patients with non-small cell lung cancer (NSCLC) was quantified by flow cytometry-based immunofluorescence analysis. ERα and ERβ expression wa
Externí odkaz:
https://doaj.org/article/236e774f4f544f8caaddb17ef842d030
Autor:
T. A. Bogush, A. S. Popova, E. A. Dudko, E. O. Ignatova, B. E. Polotsky, S. A. Tjuljandin, M. I. Davydov
Publikováno v:
Антибиотики и Химиотерапия, Vol 58, Iss 7-8, Pp 40-47 (2020)
The aim of the review was systematization of the data on discordance in expression of estrogen receptors between primary and metastatic breast cancer, different metastases and repeated analyses of the same tissue. The possible reasons for the phenome
Externí odkaz:
https://doaj.org/article/4ac97a55831a4873850c4cc5d4346603
Publikováno v:
Антибиотики и Химиотерапия, Vol 55, Iss 5-6, Pp 18-23 (2020)
Interaction of Glutoxime with P-glucoprotein (Pgp), a multiple drug resistance marker, as well as the Glutoxime impact on doxorubicin intracellular accumulation were investigated. It was shown that the Glutoxime effect on the Pgp expressing tumor cel
Externí odkaz:
https://doaj.org/article/f66f86e531b849d0a5aba4317bb23256
Autor:
A. S. Shaturova, T. A. Bogush, E. A. Dudko, G. YU. Chemeris, R. YU. Ramanauskaite, I. D. Kalganov
Publikováno v:
Антибиотики и Химиотерапия, Vol 57, Iss 5-6, Pp 11-17 (2020)
Comparability of the level and intensity of estrogen receptors ß (ERß expression in non-small cell lung cancer tissue of 32 patients was analyzed by flow cytometry using various antibodies - to the total fraction of ERß (clone 14C8) as well to the
Externí odkaz:
https://doaj.org/article/63cdb079a7e44e27baf34d4fe02124a7