Zobrazeno 1 - 10
of 801
pro vyhledávání: '"T-regulatory cell"'
Autor:
Natalija Jonić, Ivan Koprivica, Stavroula G. Kyrkou, Vasileios-Panagiotis Bistas, Christos Chatzigiannis, Nataša Radulović, Ivan Pilipović, Andjelina Jovanović, Milan B. Jovanović, Mirjana Dimitrijević, Andreas G. Tzakos, Ivana Stojanović
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type 1 diabetes (T1D) is an autoimmune disease with a strong chronic inflammatory component. One possible strategy for the treatment of T1D is to stimulate the regulatory arm of the immune response, i.e. to promote the function of tolerogenic dendrit
Externí odkaz:
https://doaj.org/article/11b51184e3184bd1b78ab93ef5a4d033
Autor:
Lanette M. Christensen, Tatiana Akimova, Liqing Wang, Rongxiang Han, Arabinda Samanta, Eros Di Giorgio, Wayne W. Hancock
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Histone deacetylases 1 and 2 play a major role in the transcriptional regulation of T-regulatory (Treg) cells via interactions with a myriad of coregulatory factors. Sin3a has been well established as a Hdac1/2 cofactor, while its role within Tregs h
Externí odkaz:
https://doaj.org/article/ce5b2e2a49e74bcd86d6e921a8749fc3
Autor:
David A. Horwitz, Ju Hua Wang, Dongin Kim, Chang Kang, Katja Brion, Sean Bickerton, Antonio La Cava
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
We have previously reported that nanoparticles (NPs) loaded with IL-2 and TGF-β and targeted to T cells induced polyclonal T regulatory cells (Tregs) that protected mice from graft-versus-host disease (GvHD). Here, we evaluated whether administratio
Externí odkaz:
https://doaj.org/article/bf7e97bd85f64b0fbcc7aa4e6dd95d31
Autor:
R. V. Vardanyan, S. G. Zakharov, T. A. Mitina, P. A. Zeynalova, Yu. Yu. Chuksina, A. V. Zakharova
Publikováno v:
Онкогематология, Vol 18, Iss 3, Pp 44-49 (2023)
Multiple primary malignant neoplasms (MPMNs) is a complex process in which the development of 2 or more neoplasms simultaneously or after a certain interval is observed. MPMNs develop independently from each other within one or more organs. Many etio
Externí odkaz:
https://doaj.org/article/3cb970c490e748dd9a7659e40dea1623
Autor:
Natalija Jonić, Ivan Koprivica, Christos M. Chatzigiannis, Antonis D. Tsiailanis, Stavroula G. Kyrkou, Eleftherios Paraskevas Tzakos, Aleksandar Pavić, Mirjana Dimitrijević, Andjelina Jovanović, Milan B. Jovanović, Sérgio Marinho, Inês Castro-Almeida, Vesna Otašević, Pedro Moura-Alves, Andreas G. Tzakos, Ivana Stojanović
Publikováno v:
Molecules, Vol 29, Iss 13, p 2988 (2024)
Aryl Hydrocarbon Receptor (AHR) ligands, upon binding, induce distinct gene expression profiles orchestrated by the AHR, leading to a spectrum of pro- or anti-inflammatory effects. In this study, we designed, synthesized and evaluated three indole-co
Externí odkaz:
https://doaj.org/article/d5220a5cc49f40db84cdc61e1239331b
Autor:
Volker Schirrmacher
Publikováno v:
Immuno, Vol 3, Iss 3, Pp 289-329 (2023)
Bone marrow is known as the site of hematopoiesis. What is not being described in textbooks of immunology is the fact that bone marrow is not only a generative, but also an antigen-responsive, immune organ. It is also a major storage site for antigen
Externí odkaz:
https://doaj.org/article/654d37d1689f40e8b8f1131e2392f9a4
Publikováno v:
Advances in Rheumatology, Vol 63, Iss 1, Pp 1-9 (2023)
Abstract Introduction/objectives Systemic lupus erythematosus (SLE) is a classic prototype of the multisystem autoimmune disease and follows a relapsing and remitting course. Triptolide is a diterpene triepoxide extracted from Chinese medicine Tripte
Externí odkaz:
https://doaj.org/article/f6c83f9340ce4b2c8b5fd1fc7ad638e6
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-14 (2022)
Abstract Background The T helper 17 (Th17)/T regulatory (Treg) cell imbalance is involved in the course of obesity and type 2 diabetes mellitus (T2DM). In the current study, the exact role of glucagon-like peptide-1 receptor agonist (GLP-1RA) exenati
Externí odkaz:
https://doaj.org/article/a0094b01db0c4992be649d9c9fafc438
Akademický článek
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Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100563- (2022)
Autism spectrum disorder (ASD) is a complicated neurodevelopmental disorder, which is categorized by deficiency of social contact and communication, and stereotyped forms of performance. Meningeal immunity conditions the immune reflection and immune
Externí odkaz:
https://doaj.org/article/4c757b03058b4c82b14d907cc214c2a1