Výsledky vyhledávání - "T-lymphopenia"

Akademický článek

Enabling immune checkpoint blockade efficacy in T-lymphopenia by restoring CD8 T cell dynamics with IL-7 cytokine therapy

Autor: Yeon-Woo Kang, Donghoon Choi, Dain Moon, Kun-Joo Lee, Youngsik Oh, Jaehyuk Yang, Siheon Jeong, Uni Park, Sun-Kyoung Im, Se Hwan Yang, Seung-Woo Lee

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionT-lymphopenia (TLP) is a frequently observed condition in cancer patients, often exacerbated by conventional chemo/radiotherapy, which impairs the efficacy of subsequent immune checkpoint blockade (ICB) therapy. This study aimed to unders

Externí odkaz: https://doaj.org/article/a694ec51210f48e0923f8ee384541068

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Akademický článek

Prognostic value of CD4+ T lymphopenia in non-small cell lung Cancer

Autor: Guillaume Eberst, Dewi Vernerey, Caroline Laheurte, Aurélia Meurisse, Vincent Kaulek, Laurie Cuche, Pascale Jacoulet, Hamadi Almotlak, Jean Lahourcade, Marie Gainet-Brun, Elizabeth Fabre, Françoise Le Pimpec-Barthes, Olivier Adotevi, Virginie Westeel

Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)

Highlights This study investigates the unknown prognostic influence of peripheral blood CD4+ T lymphopenia in non-small cell lung cancer (NSCLC) with long-term follow-up CD4+ but not CD8 + T lymphopenia was associated with poor survival in patients w

Externí odkaz: https://doaj.org/article/346b09f08c3e400eaefd24234a603f8a

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Akademický článek

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Akademický článek

Association of Apoptosis-Mediated CD4+ T Lymphopenia With Poor Outcome After Type A Aortic Dissection Surgery

Autor: Wei Luo, Jing-Jing Sun, Hao Tang, Di Fu, Zhan-Lan Hu, Hai-Yang Zhou, Wan-Jun Luo, Jun-Mei Xu, Hui Li, Ru-Ping Dai

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Background: Many patients with type A aortic dissection (AAD) show low lymphocyte counts pre-operatively. The present study investigated the prognostic values of lymphopenia and lymphocyte subsets for the postoperative major adverse events (MAEs) in

Externí odkaz: https://doaj.org/article/10343648f4ad47308a674d830652fb68

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Prognostic value of CD4+ T lymphopenia in non-small cell lung Cancer

Publikováno v: BMC Cancer
BMC Cancer, BioMed Central, 2022, 22 (1), pp.529. ⟨10.1186/s12885-022-09628-8⟩

Background There is a paucity of data regarding the prognostic influence of peripheral blood CD4+ T lymphopenia in non-small cell lung cancer (NSCLC). Therefore, we investigated the prognostic value of T lymphopenia in NSCLC. Materials Treatment-naiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1407bee78f9e564e1d09f9e3617668f1
https://pubmed.ncbi.nlm.nih.gov/35546670

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Long-Term Follow-Up of Newborns with 22q11 Deletion Syndrome and Low TRECs

Autor: Jenny Lingman Framme, Christina Lundqvist, Anna-Carin Lundell, Pauline A. van Schouwenburg, Andri L. Lemarquis, Karolina Thörn, Susanne Lindgren, Judith Gudmundsdottir, Vanja Lundberg, Sofie Degerman, Rolf H. Zetterström, Stephan Borte, Lennart Hammarström, Esbjörn Telemo, Magnus Hultdin, Mirjam van der Burg, Anders Fasth, Sólveig Oskarsdóttir, Olov Ekwall

Publikováno v: Journal of Clinical Immunology, 42, 618-633. SPRINGER/PLENUM PUBLISHERS

Background Population-based neonatal screening using T-cell receptor excision circles (TRECs) identifies infants with profound T lymphopenia, as seen in cases of severe combined immunodeficiency, and in a subgroup of infants with 22q11 deletion syndr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a75d5bd7e741da61caee4f8e2ce768
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-192261