Zobrazeno 1 - 10
of 2 878
pro vyhledávání: '"T-cell epitope"'
Autor:
Ahyar Ahmad, Abdul Karim, Rugaiyah A. Arfah, Rosana Agus, Rusdina Bte Ladju, Najdah Hidayah, Muhammad N. Massi, Astutiati Nurhasanah, Harningsih Karim, Irda Handayani, Rizal Irfandi
Publikováno v:
Emerging Science Journal, Vol 8, Iss 4, Pp 1345-1365 (2024)
The efficacy of the BCG vaccine, a widely recognized tuberculosis vaccine, has shown varying degrees of effectiveness, ranging from 0% to 80%. Sirohydrochlorin cobaltochelatase (CbiX), found in Mycobacterium tuberculosis, plays a crucial role in the
Externí odkaz:
https://doaj.org/article/49af83ed1d1e47efb6086b90dbe1589b
Autor:
Huy Quang Quach, Tamar Ratishvili, Iana H. Haralambieva, Inna G. Ovsyannikova, Gregory A. Poland, Richard B. Kennedy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Although neutralizing antibody is an established correlate of protection for measles, T cell-mediated responses play at least two critical roles in immunity to measles: first, through provision of ‘help’ enabling robust humoral immune re
Externí odkaz:
https://doaj.org/article/a03db61bd8554ab08f43e9d543dc09f0
Publikováno v:
Инфекция и иммунитет, Vol 14, Iss 3, Pp 601-608 (2024)
Antigen-specific T cells are an important part of antiviral responses, and modern influenza vaccines are designed to induce this mode of immunity. Live attenuated influenza vaccine (LAIV) is a potent inducer of T-cell immunity because of its ability
Externí odkaz:
https://doaj.org/article/0fc63e90570b40839a9dfeec2e3686f0
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTCytotoxic T lymphocytes are key for controlling viral infection. Unravelling CD8+ T cell-mediated immunity to distinct influenza virus strains and subtypes across prominent HLA types is relevant for combating seasonal infections and emerging
Externí odkaz:
https://doaj.org/article/381264734ff34a789b289a2eb1c61cc3
Autor:
Brian J. Roberts, Aimee E. Mattei, Kristina E. Howard, James L. Weaver, Hao Liu, Sandra Lelias, William D. Martin, Daniela Verthelyi, Eric Pang, Katie J. Edwards, Anne S. De Groot
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Advances in synthetic peptide synthesis have enabled rapid and cost-effective peptide drug manufacturing. For this reason, peptide drugs that were first produced using recombinant DNA (rDNA) technology are now being produced using solid- and liquid-p
Externí odkaz:
https://doaj.org/article/674dd4b85a844bff9f2eb55deb7c7e13
Autor:
Grace J. Kim, Jacob H. Elnaggar, Mallory Varnado, Amy K. Feehan, Darlene Tauzier, Rebecca Rose, Susanna L. Lamers, Maya Sevalia, Najah Nicholas, Elizabeth Gravois, Daniel Fort, Judy S. Crabtree, Lucio Miele
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Long-term immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires the identification of T-cell epitopes affecting host immunogenicity. In this computational study, we explored the CD8+ epitope diversity estimated in 27
Externí odkaz:
https://doaj.org/article/90257aa2b3b64dcf9be7305ad6c307fd
Autor:
Mohammad Hossein Shams, Seyyed Mohsen Sohrabi, Reza Jafari, Ali Sheikhian, Hossein Motedayyen, Peyman Amanolahi Baharvand, Amin Hasanvand, Ali Fouladvand, Mohammad-Ali Assarehzadegan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Allergens originated from Salsola kali (Russian thistle) pollen grains are one of the most important sources of aeroallergens causing pollinosis in desert and semi-desert regions. T-cell epitope-based vaccines (TEV) are more effective among
Externí odkaz:
https://doaj.org/article/38dba43bba6f4fe98047f986d6002cb7
Autor:
Luisa Weisbrod, Luigi Capriotti, Marco Hofmann, Valerie Spieler, Herbert Dersch, Bernd Voedisch, Peter Schmidt, Susanne Knake
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The study of peptide repertoires presented by major histocompatibility complex (MHC) molecules and the identification of potential T-cell epitopes contribute to a multitude of immunopeptidome-based treatment approaches. Epitope mapping is essential f
Externí odkaz:
https://doaj.org/article/fb27fa931af34d61becd7e97b1be039f
Publikováno v:
PeerJ Computer Science, Vol 10, p e1980 (2024)
Majority of the existing SARS-CoV-2 vaccines work by presenting the whole pathogen in the attenuated form to immune system to invoke an immune response. On the other hand, the concept of a peptide based vaccine (PBV) is based on the identification an
Externí odkaz:
https://doaj.org/article/a9689a22392a488191127bb5eb00ddbe
Autor:
Noam Erez, Hagit Achdout, Yfat Yahalom-Ronen, Shimrit Adutler-Lieber, Liat Bar-On, Erez Bar-Haim, Boaz Politi, Einat B. Vitner, Hadas Tamir, Sharon Melamed, Nir Paran, Tomer Israely
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 7944-7955 (2023)
Following viral infection, T-cells are crucial for an effective immune response to intracellular pathogens, including respiratory viruses. During the COVID-19 pandemic, diverse assays were required in pre-clinical trials to evaluate the immune respon
Externí odkaz:
https://doaj.org/article/0ddd3a5019d54197809ada8edf944d5e