Zobrazeno 1 - 10
of 60
pro vyhledávání: '"T-Y. Dora Tang"'
Autor:
Adrian Zambrano, Giorgio Fracasso, Mengfei Gao, Martina Ugrinic, Dishi Wang, Dietmar Appelhans, Andrew deMello, T-Y. Dora Tang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Our understanding of how compartmentalisation and intercellular communication can tune enzyme reactions is still in its infancy. Here, the authors show that multi-enzyme reactions within semi-permeable compartments have distinct properties compared t
Externí odkaz:
https://doaj.org/article/9a07094325254dbe8bdb7d53a21aadb9
Autor:
Nino Lauber, Ondrej Tichacek, Rudrarup Bose, Christoph Flamm, Luca Leuzzi, T-Y Dora Tang, Kepa Ruiz-Mirazo, Daniele De Martino
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106300- (2023)
Summary: Physical mechanisms of phase separation in living systems play key physiological roles and have recently been the focus of intensive studies. The strongly heterogeneous nature of such phenomena poses difficult modeling challenges that requir
Externí odkaz:
https://doaj.org/article/3877b7526eb14139988ef31c4b2d3f35
Autor:
Damian Wollny, Benjamin Vernot, Jie Wang, Maria Hondele, Aram Safrastyan, Franziska Aron, Julia Micheel, Zhisong He, Anthony Hyman, Karsten Weis, J. Gray Camp, T.‐Y. Dora Tang, Barbara Treutlein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here, the authors demonstrate that single cell RNA sequencing technology can be leveraged to characterize RNA content of individual membrane-free condensates formed by liquid-liquid phase separation processes such as coacervation.
Externí odkaz:
https://doaj.org/article/48b715e11b9444c0bb85084287f0da15
Autor:
Thomas E. Gorochowski, Sabine Hauert, Jan-Ulrich Kreft, Lucia Marucci, Namid R. Stillman, T.-Y. Dora Tang, Lucia Bandiera, Vittorio Bartoli, Daniel O. R. Dixon, Alex J. H. Fedorec, Harold Fellermann, Alexander G. Fletcher, Tim Foster, Luca Giuggioli, Antoni Matyjaszkiewicz, Scott McCormick, Sandra Montes Olivas, Jonathan Naylor, Ana Rubio Denniss, Daniel Ward
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Many complex behaviors in biological systems emerge from large populations of interacting molecules or cells, generating functions that go beyond the capabilities of the individual parts. Such collective phenomena are of great interest to bioengineer
Externí odkaz:
https://doaj.org/article/1690bd498c644b809310d629489f45c1
Autor:
Björn Drobot, Juan M. Iglesias-Artola, Kristian Le Vay, Viktoria Mayr, Mrityunjoy Kar, Moritz Kreysing, Hannes Mutschler, T-Y Dora Tang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via coacervation. Here authors demonstrate that a coacervate microenvironment supports RNA catalysis whilst selectively sequesterin
Externí odkaz:
https://doaj.org/article/ffa9ae58dd1c47ec95dba2093bd693d4
Autor:
T.‐Y. Dora Tang, Avinash J. Patil
Publikováno v:
ChemSystemsChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97074eb0fe8c79db86e433eafa2979c8
https://doi.org/10.1002/syst.202300007
https://doi.org/10.1002/syst.202300007
Building synthetic multicellular systems using non-living molecular components is a grand challenge in the field of bottom-up synthetic biology. Towards this goal, a diverse range of chemistries have been developed to provide mechanisms of intercellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7bf82d478f9936affc839e43be2c04
https://doi.org/10.1101/2023.03.04.531082
https://doi.org/10.1101/2023.03.04.531082
Publikováno v:
ACS Synthetic Biology
The ability to build synthetic cellular populations from the bottom-up provides the groundwork to realize minimal living tissues comprising single cells which can communicate and bridge scales into multicellular systems. Engineered systems made of sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1edba42288bfb19211b9c945639934a
https://doi.org/10.1021/acssynbio.1c00376
https://doi.org/10.1021/acssynbio.1c00376
Publikováno v:
Angewandte Chemie International Edition
The ability of RNA to catalyze RNA ligation is critical to its central role in many prebiotic model scenarios, in particular the copying of information during self-replication. Prebiotically plausible ribozymes formed from short oligonucleotides can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5498141c85242c31628a0f6dc83cb4
https://doi.org/10.1002/ange.202109267
https://doi.org/10.1002/ange.202109267
Condensed coacervate phases are now understood to be important features of modern cell biology, as well as valuable protocellular models in origin of life studies and synthetic biology. In each of these fields, the development of model systems with v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a2aca7235b77f9e2e216d8711be525f
https://doi.org/10.1101/2022.10.25.513667
https://doi.org/10.1101/2022.10.25.513667