Zobrazeno 1 - 10
of 38
pro vyhledávání: '"T-Lymphocytes/*physiology"'
Autor:
Bovay, Amandine, Zoete, Vincent, Dolton, Garry, Bulek, Anna M., Cole, David K., Rizkallah, Pierre J., Fuller, Anna, Beck, Konrad, Michielin, Olivier, Speiser, Daniel E., Sewell, Andrew K., Fuertes Marraco, Silvia A.
Publikováno v:
European Journal of Immunology
European journal of immunology, vol. 48, no. 2, pp. 258-272
European journal of immunology, vol. 48, no. 2, pp. 258-272
The repertoire of human αβ T-cell receptors (TCRs) is generated via somatic recombination of germline gene segments. Despite this enormous variation, certain epitopes can be immunodominant, associated with high frequencies of antigen-specific T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f7873ec14a9e47cbac9929748b7e2e26
http://europepmc.org/articles/PMC5887915
http://europepmc.org/articles/PMC5887915
Autor:
Fabian J. Theis, Maarten van den Berge, Marnix R. Jonker, Paulina M. Strzelecka, Ana Cvejic, Roser Vento-Tormo, Mirjana Efremova, Karen Affleck, Felipe A. Vieira Braga, Sarah A. Teichmann, Carlos Talavera-López, Herbert B. Schiller, Sharon Brouwer, Eirini S. Fasouli, Marijn Berg, Laura Hesse, Antoon J. M. van Oosterhout, Corry-Anke Brandsma, Gerard H. Koppelman, Lukas M. Simon, Helen V. Firth, Krzysztof Polanski, Kourosh Saeb-Parsy, Tomás Gomes, Subarna Palit, Kerstin B. Meyer, Ilias Angelidis, Marjan Luinge, Gozde Kar, Martijn C. Nawijn, Orestes A Carpaij, Wim Timens, Maximilian Strunz, Jian Jiang, Krishnaa T. Mahbubani
Publikováno v:
Nat. Med. 25, 1153-1163 (2019)
Nature Medicine, 25(7), 1153-1163. Nature Publishing Group
Nature Medicine
Nature medicine, 25(7), 1153-1163. Nature Publishing Group
Nature Medicine, 25(7), 1153-1163. Nature Publishing Group
Nature Medicine
Nature medicine, 25(7), 1153-1163. Nature Publishing Group
Human lungs enable efficient gas exchange and form an interface with the environment, which depends on mucosal immunity for protection against infectious agents. Tightly controlled interactions between structural and immune cells are required to main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6769ea082e29de0408a2fcd2b3a15168
https://www.repository.cam.ac.uk/handle/1810/292289
https://www.repository.cam.ac.uk/handle/1810/292289
Publikováno v:
Experimental Gerontology. 77:87-95
INTRODUCTION: Immunosenescence is the age-related deterioration of immunocompetence which is reflected in a poorer response to new antigens. This process is characterized by decreases in naïve T cells and increases in memory T cells. The highly prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::c0d10d6d115c084d09f9f27a3ad000f7
https://research.rug.nl/en/publications/864557da-cde6-4076-9ebd-349d4224dcf8
https://research.rug.nl/en/publications/864557da-cde6-4076-9ebd-349d4224dcf8
Publikováno v:
Experimental Gerontology. 77:87-95
Introduction Immunosenescence is the age-related deterioration of immunocompetence which is reflected in a poorer response to new antigens. This process is characterized by decreases in naive T cells and increases in memory T cells. The highly preval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32af887dae2f324adc4c1cf988ae9cee
https://doi.org/10.1016/j.exger.2016.02.005
https://doi.org/10.1016/j.exger.2016.02.005
Autor:
Daniela Wesch, Matthias Peipp, Andreas Humpe, J.G.J. van de Winkel, P. W. Parren, Dieter Kabelitz, Anja Muskulus, Renate Burger, Christian Kellner, Sebastian Lutz, Martin Gramatzki, Hans-Heinrich Oberg
Publikováno v:
Peipp, M, Wesch, D, Oberg, H H, Lutz, S, Muskulus, A, van de Winkel, J G J, Parren, P W H I, Burger, R, Humpe, A, Kabelitz, D, Gramatzki, M & Kellner, C 2017, ' CD20-Specific Immunoligands Engaging NKG2D Enhance γδ T Cell-Mediated Lysis of Lymphoma Cells ', Scandinavian Journal of Immunology, vol. 86, no. 4, pp. 196-206 . https://doi.org/10.1111/sji.12581
Human γδ T cells are innate-like T cells which are able to kill a broad range of tumor cells and thus may have potential for cancer immunotherapy. The activating receptor natural killer group 2 member D (NKG2D) plays a key role in regulating immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446e5c0ed34b1f93fde1e38c1796209d
https://pubmed.ncbi.nlm.nih.gov/28708284
https://pubmed.ncbi.nlm.nih.gov/28708284
Autor:
Danilo Presotto, Olivier Michielin, Nathalie Rufer, Lukas Baitsch, Daniel E. Speiser, Petra Baumgaertner, Michael Hebeisen, Pedro Romero
Publikováno v:
Journal of Clinical Investigation, vol. 123, no. 3, pp. 1044-1056
J Clin Invest
The Journal of clinical investigation
J Clin Invest
The Journal of clinical investigation
Anti-self/tumor T cell function can be improved by increasing TCR-peptide MHC (pMHC) affinity within physiological limits, but paradoxically further increases (K(d) < 1 μM) lead to drastic functional declines. Using human CD8(+) T cells engineered w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd8312a40cacc009502b9ad194dae7e
https://doi.org/10.1172/jci65325
https://doi.org/10.1172/jci65325
Autor:
Marc R Suter, Christophe Gattlen, Romain-Daniel Gosselin, Christine B. Clarke, Guylène Kirschmann, Nicolas Piller, Isabelle Decosterd, Marie Pertin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 3; Pages: 352
International Journal of Molecular Sciences, Vol 17, Iss 3, p 352 (2016)
International journal of molecular sciences, vol. 17, no. 3, pp. 352
International Journal of Molecular Sciences; Volume 17; Issue 3; Pages: 352
International Journal of Molecular Sciences, Vol 17, Iss 3, p 352 (2016)
International journal of molecular sciences, vol. 17, no. 3, pp. 352
The immune system is involved in the development of neuropathic pain. In particular, the infiltration of T-lymphocytes into the spinal cord following peripheral nerve injury has been described as a contributor to sensory hypersensitivity. We used the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992ef7051f68f3cd2d687a45906d9427
http://europepmc.org/articles/PMC4813213
http://europepmc.org/articles/PMC4813213
Autor:
Grebing, Manuela, Nielsen, Helle H, Fenger, Christina D, T Jensen, Katrine, von Linstow, Christian U, Clausen, Bettina H, Söderman, Anders Martin, Lambertsen, Kate L, Thomassen, Mads, Kruse, Torben A, Finsen, Bente
Publikováno v:
Grebing, M, Nielsen, H H, Fenger, C D, T Jensen, K, von Linstow, C U, Clausen, B H, Söderman, A M, Lambertsen, K L, Thomassen, M, Kruse, T A & Finsen, B 2016, ' Myelin-specific T cells induce interleukin-1beta expression in lesion-reactive microglial-like cells in zones of axonal degeneration ', Glia, vol. 64, no. 3, pp. 407-424 . https://doi.org/10.1002/glia.22937
Infiltration of myelin-specific T cells into the central nervous system induces the expression of proinflammatory cytokines in patients with multiple sclerosis (MS). We have previously shown that myelin-specific T cells are recruited into zones of ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3062::744a98a89635bdfcdb89f107c96e8e16
https://portal.findresearcher.sdu.dk/da/publications/49e40e0b-b1b6-49be-b1ad-a65d0505e5d2
https://portal.findresearcher.sdu.dk/da/publications/49e40e0b-b1b6-49be-b1ad-a65d0505e5d2
Autor:
Augusto Faustino, Virgínia Maria Dinis Carvalhais, Bruna Miyazawa, Begoña Pérez-Cabezas, Alexandra Correia, Nuno Cerca, Gerald B. Pier, Anabela Cordeiro-da-Silva, Luzia Teixeira, Manuel Vilanova, Pedro Ferreirinha, Angela França
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Poly-N-acetyl glucosamine (PNAG) is a major component of Staphylococcus epidermidis biofilms extracellular matrix. However, it is not yet clear how this polysaccharide impacts the host immune response and infection-associated pathology. Faster neutro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061ad046f1f56783ba9d5da5c31440cc
https://repositorio-aberto.up.pt/handle/10216/118207
https://repositorio-aberto.up.pt/handle/10216/118207
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