Zobrazeno 1 - 10
of 15
pro vyhledávání: '"T-Lymphocyte Subsets/metabolism"'
Autor:
S. Almeida, Afonso P. Basto, Vanessa G. Oliveira, Kalet León, Rita F. Santos, Luis Graca, Carine M. Gonçalves, Jesus Corria-Osorio, Raquel F. Freitas, Alexandre M. Carmo, Tânia Carvalho
Publikováno v:
EBioMedicine
In recent years molecules involved on the immune synapse became successful targets for therapeutic immune modulation. CD6 has been extensively studied, yet, results regarding CD6 biology have been controversial, in spite of the ubiquitous presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000c3982119e1bc616c460837851466b
https://doi.org/10.1016/j.ebiom.2019.08.008
https://doi.org/10.1016/j.ebiom.2019.08.008
Autor:
Mirjam Lutz, Ekaterina Friebel, Roland S. Liblau, Antoine Roquilly, Guillaume Martin-Blondel, Manfred Claassen, Benjamin Gaborit, Manuel Kauffmann, Sepideh Babaei, Donatella De Feo, Nicolás Gonzalo Núñez, Nisar P. Malek, Chiara Alberti, Sally Al-Hajj, Susanne Unger, Siri Goepel, Ikram Ayoub, Helene A. Häberle, Jakob Nilsson, Nicole Puertas Jurado, Peter Rosenberger, Stefanie Kreutmair, Sinduya Krishnarajah, Burkhard Becher, Michael Bitzer, Florian Ingelfinger
Publikováno v:
Immunity
Immunity, 2021, 54 (7), pp.1578-1593.e5. ⟨10.1016/j.immuni.2021.05.002⟩
Immunity, 2021, 54 (7), pp.1578-1593.e5. ⟨10.1016/j.immuni.2021.05.002⟩
Immune profiling of COVID-19 patients has identified numerous alterations in both innate and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or driven by a general inflammatory response shared across severely ill pneumoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a70271704dd1c2b9bc69005e3664513
https://doi.org/10.1016/j.immuni.2021.05.002
https://doi.org/10.1016/j.immuni.2021.05.002
Autor:
Guillaume Martin-Blondel, Jacques Izopet, Mary Requena, Bertrand Suc, Laurent Alric, Manon Nayrac, Nicolas Carrere, Pierre Delobel, Karl Barange, Claire Loiseau, Michelle Cazabat
Publikováno v:
Mucosal Immunology
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
International audience; Gut CD4+ T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7063cc54ac3d26c97d0c23435a80444c
https://ut3-toulouseinp.hal.science/hal-03157449
https://ut3-toulouseinp.hal.science/hal-03157449
Autor:
Kent Riemondy, Anjana Rao, Brian P. O'Connor, S. Harsha Krovi, Laurent Gapin, Adam R. Lefferts, Jay R. Hesselberth, Leonard L. Dragone, Catherine Halluszczak, Philippa Marrack, Jingjing Zhang, Lisa K. Peterson, Kathryn D. Tuttle, Laura Harmacek, James P. Scott-Browne, Romain Bedel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650
During development in the thymus, invariant natural killer T (iNKT) cells commit to one of three major functionally different subsets, iNKT1, iNKT2, and iNKT17. Here, we show that T cell antigen receptor (TCR) signal strength governs the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89e4c35d3becfa75c6b45c62a82a633
http://link.springer.com/article/10.1038/s41467-018-05026-6
http://link.springer.com/article/10.1038/s41467-018-05026-6
Autor:
Marit Renée Myhre, Theodossis A. Theodossiou, Pierre Dillard, Gunnar Kvalheim, Nadia Mensali, Else Marit Inderberg, Sébastien Wälchli, June Helen Myklebust, Anne Fåne, Susanne Lorenz, Michael Hebeisen, Gustav Gaudernack
Publikováno v:
EBioMedicine
EBioMedicine, vol. 40, pp. 106-117
EBioMedicine, vol. 40, pp. 106-117
Background Adoptive T-cell transfer of therapeutic TCR holds great promise to specifically kill cancer cells, but relies on modifying the patient's own T cells ex vivo before injection. The manufacturing of T cells in a tailor-made setting is a long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd5f8aa4294932b7d12784781053737
http://hdl.handle.net/10852/74614
http://hdl.handle.net/10852/74614
Autor:
Daniel J. Powell, Lana E. Kandalaft, Renee Frank, Thomas Garrabrant, Priyanka Duttagupta, Hongzhe Li, Denarda Dangaj, Davide Bedognetti, Ian S. Hagemann, George Coukos, Emese Zsiros, Ena Wang, Michael Feldman, Janos L. Tanyi, Francesco M. Marincola, Carl H. June, Lin Zhang, Bruce L. Levine
Publikováno v:
Clinical Cancer Research, vol. 21, no. 12, pp. 2840-2850
Purpose: Chemokines are implicated in T-cell trafficking. We mapped the chemokine landscape in advanced stage ovarian cancer and characterized the expression of cognate receptors in autologous dendritic cell (DC)–vaccine primed T cells in the conte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0080014a9788b518e2b39aae8b14b6
https://doi.org/10.1158/1078-0432.ccr-14-2777
https://doi.org/10.1158/1078-0432.ccr-14-2777
Autor:
Christophe Paget, Maya Hassane, Emmanuel C. Patin, Sébastien Fleury, Daphnée Soulard, François Trottein, Christelle Faveeuw, David Dombrowicz
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (1), pp.195-204. ⟨10.1158/0008-5472.CAN-17-1416⟩
Cancer Research, 2018, 78 (1), pp.195-204. ⟨10.1158/0008-5472.CAN-17-1416⟩
Cancer Research, American Association for Cancer Research, 2018, 78 (1), pp.195-204. ⟨10.1158/0008-5472.CAN-17-1416⟩
Cancer Research, 2018, 78 (1), pp.195-204. ⟨10.1158/0008-5472.CAN-17-1416⟩
The protumoral activity of γδT17 cells has recently emerged in a wide variety of solid malignancies, including breast cancer. These cells exert their detrimental functions by promoting tumor growth, angiogenesis, and subsequent metastasis developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e09b4212303852f721fd35a700bae12
https://hal-univ-tours.archives-ouvertes.fr/hal-03534418
https://hal-univ-tours.archives-ouvertes.fr/hal-03534418
Autor:
Daniel E. Speiser, Leticia Barba, Amandine Legat, Lukas Baitsch, Nathalie Rufer, Hanifa Bouzourene, Sunil K. Raghav, Petra Baumgaertner, Pedro Romero, Bart Deplancke, Sébastien Wieckowski, Estelle Devevre
Publikováno v:
Journal of Clinical Investigation, vol. 121, no. 6, pp. 2350-2360
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (6), pp.2350-2360. ⟨10.1172/JCI46102⟩
The Journal of clinical investigation
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (6), pp.2350-2360. ⟨10.1172/JCI46102⟩
The Journal of clinical investigation
International audience; In chronic viral infections, CD8⁺ T cells become functionally deficient and display multiple molecular alterations. In contrast, only little is known of self- and tumor-specific CD8⁺ T cells from mice and humans. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fae003bc650a938f54e2ed5ba1e640
https://doi.org/10.1172/jci46102
https://doi.org/10.1172/jci46102
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (12), pp.5674-5680. ⟨10.4049/jimmunol.1402457⟩
Journal of Immunology, 2015, 194 (12), pp.5674-5680. ⟨10.4049/jimmunol.1402457⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (12), pp.5674-5680. ⟨10.4049/jimmunol.1402457⟩
Journal of Immunology, 2015, 194 (12), pp.5674-5680. ⟨10.4049/jimmunol.1402457⟩
Citrullinated peptides are major targets of disease-specific autoantibodies in rheumatoid arthritis. Currently, citrullinated peptides are used as biomarkers for diagnosing rheumatoid arthritis by measuring anti-citrullinated protein Ab (ACPA) titers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d48c500831826e67c9549df5de0617
https://pubmed.ncbi.nlm.nih.gov/25964493
https://pubmed.ncbi.nlm.nih.gov/25964493
Autor:
Rocío Ramos-Medina, Bárbara Alonso, Armanda Casrouge, Janet Vega, Matthew L. Albert, Marta Tejera-Alhambra, Silvia Sánchez-Ramón, Clara de Andrés
Publikováno v:
Clinical Immunology
Clinical Immunology, Elsevier, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, Elsevier, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
International audience; Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073eb035795c59681898d72ef93eb841