Zobrazeno 1 - 10
of 80
pro vyhledávání: '"T-Lymphocyte Subsets/immunology"'
Autor:
S. Almeida, Afonso P. Basto, Vanessa G. Oliveira, Kalet León, Rita F. Santos, Luis Graca, Carine M. Gonçalves, Jesus Corria-Osorio, Raquel F. Freitas, Alexandre M. Carmo, Tânia Carvalho
Publikováno v:
EBioMedicine
In recent years molecules involved on the immune synapse became successful targets for therapeutic immune modulation. CD6 has been extensively studied, yet, results regarding CD6 biology have been controversial, in spite of the ubiquitous presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000c3982119e1bc616c460837851466b
https://doi.org/10.1016/j.ebiom.2019.08.008
https://doi.org/10.1016/j.ebiom.2019.08.008
Autor:
Laetitia Aerts, Violette Dirix, Véronique Corbière, Emmanuelle Petit, Nicolas Dauby, Elodie Selis, Kaatje Smits, Mahavir Singh, Camille Locht, Anne Van Praet, Françoise Mascart
Publikováno v:
The Journal of immunology, 202 (2
The Journal of Immunology
The Journal of Immunology
Heparin-binding hemagglutinin (HBHA), a surface protein of Mycobacterium tuberculosis, is an attractive vaccine candidate and marker of protective immunity against tuberculosis, although the mechanisms underlying this protective immunity are not full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebfb699ca858f05e488d2cf829492a9
https://doi.org/10.4049/jimmunol.1800840
https://doi.org/10.4049/jimmunol.1800840
Autor:
Massimo, Andreatta, Jesus, Corria-Osorio, Sören, Müller, Rafael, Cubas, George, Coukos, Santiago J, Carmona
Publikováno v:
Nature communications, vol. 12, no. 1, pp. 2965
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Single-cell RNA sequencing (scRNA-seq) has revealed an unprecedented degree of immune cell diversity. However, consistent definition of cell subtypes and cell states across studies and diseases remains a major challenge. Here we generate reference T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7aa6ca7323ee966e64c8b77a30c42f7f
https://serval.unil.ch/notice/serval:BIB_BE1D257DF142
https://serval.unil.ch/notice/serval:BIB_BE1D257DF142
Autor:
Terhi Ruohtula, Anita Kondrashova, Jussi Lehtonen, Sami Oikarinen, Anu-Maaria Hämäläinen, Onni Niemelä, Aleksandr Peet, Vallo Tillmann, Janne K. Nieminen, Jorma Ilonen, Mikael Knip, Outi Vaarala, Heikki Hyöty, the DIABIMMUNE Study Group, Taina Härkönen, Samppa Ryhänen, Heli Siljander, Katriina Koski, Matti Koski, Janne Nieminen, Anne Ormisson, Valentina Ulich, Elena Kuzmicheva, Sergei Mokurov, Svetlana Markova, Svetlana Pylova, Marina Isakova, Elena Shakurova, Vladimir Petrov, Natalya V. Dorshakova, Tatyana Karapetyan, Tatyana Varlamova, Minna Kiviniemi, Kristi Alnek, Helis Janson, Raivo Uibo, Tiit Salum, Erika von Mutius, Juliane Weber, Helena Ahlfors, Henna Kallionpää, Essi Laajala, Riitta Lahesmaa, Harri Lähdesmäki, Robert Moulder, Hanna Honkanen, Hermie J. M. Harmsen, Marcus C. De Goffau, Gjalt Welling, Kirsi Alahuhta, Suvi M. Virtanen
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology, 11:567046. Frontiers Media SA
Frontiers in Immunology
Frontiers in Immunology, 11:567046. Frontiers Media SA
Frontiers in Immunology
Early childhood infections have been implicated in the development of immune-mediated diseases, such as allergies, asthma, and type 1 diabetes. We set out to investigate the immunomodulatory effects of early viral infections experienced before the ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef6aec3d5c5933745a4d04fc2deb4a0
https://www.frontiersin.org/articles/10.3389/fimmu.2020.567046/full
https://www.frontiersin.org/articles/10.3389/fimmu.2020.567046/full
Autor:
Mirjam Lutz, Ekaterina Friebel, Roland S. Liblau, Antoine Roquilly, Guillaume Martin-Blondel, Manfred Claassen, Benjamin Gaborit, Manuel Kauffmann, Sepideh Babaei, Donatella De Feo, Nicolás Gonzalo Núñez, Nisar P. Malek, Chiara Alberti, Sally Al-Hajj, Susanne Unger, Siri Goepel, Ikram Ayoub, Helene A. Häberle, Jakob Nilsson, Nicole Puertas Jurado, Peter Rosenberger, Stefanie Kreutmair, Sinduya Krishnarajah, Burkhard Becher, Michael Bitzer, Florian Ingelfinger
Publikováno v:
Immunity
Immunity, 2021, 54 (7), pp.1578-1593.e5. ⟨10.1016/j.immuni.2021.05.002⟩
Immunity, 2021, 54 (7), pp.1578-1593.e5. ⟨10.1016/j.immuni.2021.05.002⟩
Immune profiling of COVID-19 patients has identified numerous alterations in both innate and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or driven by a general inflammatory response shared across severely ill pneumoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a70271704dd1c2b9bc69005e3664513
https://doi.org/10.1016/j.immuni.2021.05.002
https://doi.org/10.1016/j.immuni.2021.05.002
Autor:
Guillaume Martin-Blondel, Jacques Izopet, Mary Requena, Bertrand Suc, Laurent Alric, Manon Nayrac, Nicolas Carrere, Pierre Delobel, Karl Barange, Claire Loiseau, Michelle Cazabat
Publikováno v:
Mucosal Immunology
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
International audience; Gut CD4+ T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7063cc54ac3d26c97d0c23435a80444c
https://ut3-toulouseinp.hal.science/hal-03157449
https://ut3-toulouseinp.hal.science/hal-03157449
Autor:
Véronique Adoue, Olivier Joffre
Publikováno v:
médecine/sciences
médecine/sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, EDP Sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, EDP Sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
Upon priming by dendritic cells, naïve CD4 T lymphocytes are exposed to distinct molecular environments depending on the nature of the pathological stimulus. In response, they mobilize different gene networks that establish lineage-specific developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d8bbf56b7f22d0ec282cc76e4db22f
https://doi.org/10.1051/medsci/2020022
https://doi.org/10.1051/medsci/2020022
Autor:
Kent Riemondy, Anjana Rao, Brian P. O'Connor, S. Harsha Krovi, Laurent Gapin, Adam R. Lefferts, Jay R. Hesselberth, Leonard L. Dragone, Catherine Halluszczak, Philippa Marrack, Jingjing Zhang, Lisa K. Peterson, Kathryn D. Tuttle, Laura Harmacek, James P. Scott-Browne, Romain Bedel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650
Nature Communications
Nature communications, vol. 9, no. 1, pp. 2650
During development in the thymus, invariant natural killer T (iNKT) cells commit to one of three major functionally different subsets, iNKT1, iNKT2, and iNKT17. Here, we show that T cell antigen receptor (TCR) signal strength governs the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89e4c35d3becfa75c6b45c62a82a633
http://link.springer.com/article/10.1038/s41467-018-05026-6
http://link.springer.com/article/10.1038/s41467-018-05026-6
Autor:
Viktor H. Koelzer, Didier Lardinois, Kirsten D. Mertz, Spasenija Savic Prince, Ping-Chih Ho, Jonathan C Hanhart, Daniela S. Thommen, Alfred Zippelius, Catherine Schill, Marcel P. Trefny, Vaios Karanikas, Sarah Dimeloe, Ton N. Schumacher, Mark Wiese, Andreas Roller, Petra Herzig, Christoph Hess, Christian Klein, Anna Kiialainen
Publikováno v:
Nature medicine
Nature medicine, vol. 24, no. 7, pp. 994-1004
Nature Medicine
Nature medicine, vol. 24, no. 7, pp. 994-1004
Nature Medicine
Evidence from mouse chronic viral infection models suggests that CD8 + T cell subsets characterized by distinct expression levels of the receptor PD-1 diverge in their state of exhaustion and potential for reinvigoration by PD-1 blockade. However, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a11afb8d7bbc106488bcd31ac01e17
http://europepmc.org/articles/PMC6110381
http://europepmc.org/articles/PMC6110381
Publikováno v:
Immunology letters
Identification of antigen specificity of CD4 T cells is instrumental in understanding adaptive immune responses in health and disease. The high diversity of CD4 T cell repertoire combined with the functional heterogeneity of the compartment poses a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a58a5b93f5c593e09fb95b2159eec8
https://pubmed.ncbi.nlm.nih.gov/31881234
https://pubmed.ncbi.nlm.nih.gov/31881234