Zobrazeno 1 - 10
of 369 908
pro vyhledávání: '"T-Cell Receptor"'
T cell receptor signaling must operate reliably under tight time constraints. While assuming quite different mechanisms, two prominent models of T cell receptor activation, kinetic segregation and kinetic proofreading, both introduce a distinct time
Externí odkaz:
http://arxiv.org/abs/2412.06773
Identifying T-cell receptors (TCRs) that interact with antigenic peptides provides the technical basis for developing vaccines and immunotherapies. The emergent deep learning methods excel at learning antigen binding patterns from known TCRs but stru
Externí odkaz:
http://arxiv.org/abs/2411.17798
Autor:
Cieslak, Cassandra1 (AUTHOR), Hain, Carsten2 (AUTHOR), Rückert-Reed, Christian2 (AUTHOR), Busche, Tobias2 (AUTHOR), Klages, Levin Joe2 (AUTHOR), Schaper-Gerhardt, Katrin1 (AUTHOR), Gutzmer, Ralf1 (AUTHOR), Kalinowski, Jörn2 (AUTHOR) joern@cebitec.uni-bielefeld.de, Stadler, Rudolf1 (AUTHOR) joern@cebitec.uni-bielefeld.de
Publikováno v:
Cancers. Nov2024, Vol. 16 Issue 21, p3700. 12p.
Autor:
Linhu Hui1, Fengli Wu1, Yuanyuan Xu1, Guangjun Yang2, Qiaorong Luo3, Yangyang Li1, Long Ma1, Xinsheng Yao1, Jun Li1 huosu2014@163.com
Publikováno v:
Animal Bioscience. Dec2024, Vol. 37 Issue 12, p2178-2188. 11p.
Autor:
Yang, Meng1 (AUTHOR), He, Dan1 (AUTHOR), Sun, Yu2 (AUTHOR), Guo, Yunquan1 (AUTHOR), Ma, Yu3 (AUTHOR), Feng, Lin2 (AUTHOR), Liu, Meng1 (AUTHOR) liuxiaomeng198154@163.com
Publikováno v:
Journal of Translational Medicine. 11/27/2024, Vol. 22 Issue 1, p1-13. 13p.
Autor:
Grundy, Erin E.1,2,3 (AUTHOR), Shaw, Lauren C.4 (AUTHOR), Wang, Loretta1,2 (AUTHOR), Lee, Abigail V.1,2,3 (AUTHOR), Argueta, James Castro5 (AUTHOR), Powell Jr, Daniel J.4 (AUTHOR), Ostrowski, Mario6 (AUTHOR), Jones, R. Brad7 (AUTHOR), Cruz, C. Russell Y.2,3,8 (AUTHOR), Gordish-Dressman, Heather5,9 (AUTHOR), Chappell, Nicole P.2 (AUTHOR), Bollard, Catherine M.2,3,8 (AUTHOR), Chiappinelli, Katherine B.1,2,3 (AUTHOR) kchiapp1@email.gwu.edu
Publikováno v:
Mobile DNA. 10/9/2024, Vol. 15 Issue 1, p1-18. 18p.
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a malignant neoplasm with detrimental implications for human health. The landscape of ESCC therapy has been revolutionized by the introduction of immunotherapy, specifically involving i
Externí odkaz:
https://doaj.org/article/cbff68607cde4c7eb4022dd69fc6cb51
Autor:
Erin E. Grundy, Lauren C. Shaw, Loretta Wang, Abigail V. Lee, James Castro Argueta, Daniel J. Powell, Mario Ostrowski, R. Brad Jones, C. Russell Y. Cruz, Heather Gordish-Dressman, Nicole P. Chappell, Catherine M. Bollard, Katherine B. Chiappinelli
Publikováno v:
Mobile DNA, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transposable elements (TEs) are often expressed at higher levels in tumor cells than normal cells, implicating these genomic regions as an untapped pool of tumor-associated antigens. In ovarian cancer (OC), protein from the TE ERV-K is frequ
Externí odkaz:
https://doaj.org/article/ae60226c036b4df8a06919f4dc2441a1
Autor:
Sehoon Hong, Kyurae Kim, Young-Ri Shim, Jiyeon Park, Sung Eun Choi, Hyungyu Min, Seulgi Lee, Ji-Joon Song, Suk-Jo Kang, Won-Il Jeong, Rho Hyun Seong, Seyun Kim
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Phospholipase C gamma 1 (PLCγ1) is an important mediator of the T cell receptor (TCR) and growth factor signaling. PLCγ1 is activated by Src family kinases (SFKs) and produces inositol 1,4,5-triphosphate (InsP3) from phosphatidy
Externí odkaz:
https://doaj.org/article/29ed39e31ccc47c68fe3da67de62d33d