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pro vyhledávání: '"T-15"'
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Autor:
Jingqiao Qiao, Caixia Han, Li Yu, Hong Wang, Ruiqi Wang, Xiangyu Meng, Shujiao He, Yonghui Li, Xuefeng Gao
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Rho GTPase activating protein 9 (ARHGAP9) is expressed in various types of cancers and can inactivate Rho GTPases that mainly regulate cytoskeletal dynamics. However, the exact role of ARHGAP9 in acute myeloid leukemia (AML) has yet to be
Publikováno v:
Bosnian Journal of Basic Medical Sciences
Bosnian Journal of Basic Medical Sciences (2020)
Bosnian Journal of Basic Medical Sciences (2020)
Most acute promyelocytic leukemias (APL) are characterized by reciprocal translocations t(15;17)(q22;21), which results in the fusion of the promyelocytic leukemia protein (PML) gene at 15q22 with retinoic acid receptor a (RARα) gene at 17q21. Howev
Autor:
Jun Lee, Young Eun Kim
Publikováno v:
Laboratory Medicine Online. 11:211-213
Autor:
Hossein Ayatollahi, Omolbanin Sargazi-Aval, Ali Fani, Payam Siyadat, Maryam Sheikhi, Mohammad Hadi Sadeghian, Ali Bazi
Publikováno v:
Iranian Journal of Pathology
Background & Objective: Acute promyelocytic leukemia (APL) with t(15;17)(q22;q12) is a relatively common subtype of acute myeloid leukemia (AML). Here, our objective was to ascertain the survival of patients with this leukemia in north-east of Iran.
Autor:
Junqing Xu, Yanhong Zhang, Limei Yu, Riming Liu, Yongming Liu, Lina Chu, Weihua Wang, Yangyang Zhang, Li Ma, Yimin Xu
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-5 (2020)
Molecular Cytogenetics
Molecular Cytogenetics
Background Chromosomal rearrangements in addition to t(15;17) have been reported in 25-40% of APL patients, with a large predominance of trisomy 8. Other abnormalities are far less frequent, particularly as ider(17), and the prognostic significance i
Publikováno v:
Pathology. 52:273-276
Publikováno v:
Cancer Biol Ther
Acute promyelocytic leukemia (APL) is characterized by the presence of promyelocytic leukemia-retinoic acid receptor α (PML-RARα) fusion gene, which is formed following the specific chromosomal translocation t(15;17)(q22;q21). However, cases with P
Publikováno v:
Intractable Rare Dis Res
Acute promyelocytic leukemia (APL) is characterized by the translocation t (15 ; 17) (q22 ; q21) cytogenetic abnormality in the majority of cases. In most of the cases the cells of APL have normal, diploid karyotype. There are very few cases presente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbee9207a61eb555b8850b15de50343
https://www.bib.irb.hr/1114541
https://www.bib.irb.hr/1114541
Autor:
Depei Wu, Xiaoyu Xu, Lijun Wen, Jinlan Pan, Zhao Zeng, Changgeng Ruan, Dewan Zhao, Zheng Wang, Li Yao, Man Wang, Jingzhi Shen, Jia Zhilin, Guangquan Mo, Xiaoqian Chen, Cai Wei, Yi Xu, Suning Chen, Ling Zhang, Wang Yao, Xiaomeng Chi, Zhen Shen
Publikováno v:
Molecular carcinogenesisREFERENCES. 60(2)
Acute promyelocytic leukemia (APL) is a unique disease entity in acute myeloid leukemia, characterized by PML-RARA fusion gene, which is generated by chromosomal translocation t(15;17)(q24;q21). We identified TNRC18-RARA as novel RARA fusion in resem