Zobrazeno 1 - 10
of 815
pro vyhledávání: '"T helper 17 cells"'
Autor:
WU Dingjiang, ZHANG Xiufeng
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 8, Pp 1165-1169 (2024)
Severe asthma is a chronic inflammatory disease that is not sensitive to glucocorticoid treatment. In the pathogenesis of severe asthma, T helper cell 17(Th17) and interleukin 17 (IL-17) play an important role, mainly by aggregating the infiltration
Externí odkaz:
https://doaj.org/article/4c101f3740834bd5b691668392cebd41
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 57 (2024)
Jun N-terminal kinase pathway-associated phosphatase (JKAP) regulates CD4+ T-cell differentiation and immunity, which are linked to mental disorders. This study aimed to explore the relationships between JKAP and T helper 17 (Th17)/regulatory T (Treg
Externí odkaz:
https://doaj.org/article/772534bb4e2c4c5fb770c087a41400fb
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract Background Bone regeneration is a well‐regulated dynamic process, of which the prominent role of the immune system on bone homeostasis is more and more revealed by recent research. Before fully activation of the bone remodeling cells, the
Externí odkaz:
https://doaj.org/article/83f0a87045f74abea030148f713dfe51
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRheumatoid arthritis (RA) is an autoimmune disease with various subtypes. Among these, seronegative rheumatoid arthritis (SnRA), distinguished by its distinctive seronegative antibody phenotype, presents clinical diagnosis and treatment cha
Externí odkaz:
https://doaj.org/article/cc4eff039d504f86b4c0c49931308da2
Autor:
Rahim Iranzad, Maryam Hosseini, Mahdi Bagheri, Mohammad Sadegh Soltani-Zangbar, Mohammadbagher Pirouzpanah, Negin Biglari, Mohammadali Zolfaghari, Arash Khaki, Leili Aghebati-Maleki, Leila Roshangar, Elham Badihi, Farshid Afandideh, Reihane Shahabirad, Ali Akbar Shekarchi, Javad Ahmadian Heris, Jalal Etemadi, Mehdi Yousefi
Publikováno v:
Molecular and Cellular Probes, Vol 76, Iss , Pp 101969- (2024)
The progression and pathogenesis of membranous glomerulonephritis (MGN) are inextricably linked to chronic inflammation. Despite improving clinical remission rates due to the application of cyclophosphamide (CYC), treatment of MGN still requires furt
Externí odkaz:
https://doaj.org/article/8be28ab0abc447cbaeccc5cd75faab73
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
ObjectiveLeucine-rich α-2 glycoprotein 1 (LRG1) promotes inflammation and myocardial injury, but its clinical role in ST-elevation myocardial infarction (STEMI) is rarely disclosed. Herein, this prospective study aimed to explore the value of plasma
Externí odkaz:
https://doaj.org/article/faf788c236c1405aad4f080d6ebd0aa1
Autor:
Sayuri Yoshikawa, Kurumi Taniguchi, Haruka Sawamura, Yuka Ikeda, Tomoko Asai, Ai Tsuji, Satoru Matsuda
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 4, Pp 556-568 (2023)
Hepatocellular carcinoma (HCC) constitutes an extremely malignant form of primary liver cancer. Intricate connections linking to the immune system might be associated with the pathogenesis of HCC. Meanwhile, immunotherapy with immune checkpoint inhib
Externí odkaz:
https://doaj.org/article/31a7c70a785741fa9481565ec1ae9628
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 2, Pp n/a-n/a (2024)
Abstract Introduction Regulatory T cells (Tregs) play an important role in inflammatory bowel diseases (IBDs) through modulating intestinal inflammation. However, the factors affecting Treg function and plasticity during IBD progression are not thoro
Externí odkaz:
https://doaj.org/article/e22afabf396e490781d9ac216421f9b0
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveTo assess the effect of B cell depletion therapy (BCDT) on circulating T follicular helper (cTfh) and circulating T helper 17 (cTh17) cells and its relation to clinical improvement in patients with myasthenia gravis (MG).Methods28 anti-AchR
Externí odkaz:
https://doaj.org/article/74b3c04d5eef4771b608663ad58fdf47
Publikováno v:
Autoimmunity, Vol 56, Iss 1 (2023)
The factors regulating the heterogeneity of interleukin-17A (IL-17A)-expressing CD4+ T cells in inflammatory bowel diseases remain unclear. In the current study, we characterised the expression and function of zinc finger protein 189 (ZFP189) in a mu
Externí odkaz:
https://doaj.org/article/a6540a58f6e14ed8b035d1e3e7077964