Zobrazeno 1 - 10
of 53
pro vyhledávání: '"T cell-based immunotherapy"'
Autor:
Zihao Zhou, Jiarong Zheng, Ye Lu, Zizhao Mai, Yunfan Lin, Pei Lin, Yucheng Zheng, Xu Chen, Rongwei Xu, Xinyuan Zhao, Li Cui
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract CD8+ T cells are integral to the effective management of cancer and infectious diseases due to their cytotoxic functions. The efficacy of these cells is profoundly influenced by their metabolic state, which regulates their activation, differ
Externí odkaz:
https://doaj.org/article/bf49ad5f6f5c4284b1e249956fd8cfa5
Autor:
Alexandra Kegler, Laura Drewitz, Claudia Arndt, Cansu Daglar, Liliana Rodrigues Loureiro, Nicola Mitwasi, Christin Neuber, Karla Elizabeth González Soto, Tabea Bartsch, Larysa Baraban, Holger Ziehr, Markus Heine, Annabel Nieter, Andres Moreira-Soto, Arne Kühne, Jan Felix Drexler, Barbara Seliger, Markus Laube, Domokos Máthé, Bernadett Pályi, Polett Hajdrik, László Forgách, Zoltán Kis, Krisztián Szigeti, Ralf Bergmann, Anja Feldmann, Michael Bachmann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to millions of infections and deaths worldwide. As this virus evolves rapidly, there is a high need for treatment options that
Externí odkaz:
https://doaj.org/article/6f9dbf914b914345892894df2414c939
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunotherapy has emerged as a promising approach to combat immunosuppressive tumor microenvironment (TME) for improved cancer treatment. FDA approval for the clinical use of programmed death receptor 1/programmed death-ligand 1 (PD-1/PD-L1) inhibito
Externí odkaz:
https://doaj.org/article/9b093e038ab14005960c83d76ee030b4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
T lymphocytes function as major players in antigen-mediated cytotoxicity and have become powerful tools for exploiting the immune system in tumor elimination. Several types of T cell-based immunotherapies have been prescribed to cancer patients with
Externí odkaz:
https://doaj.org/article/f4c1c0ff29124dabb92a2b0399a93231
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chimeric antigen receptors (CARs) or bispecific antibodies (bsAbs) redirected T cell against tumors is one of the most promising immunotherapy approaches. However, insufficient clinical outcomes are still observed in treatments of both solid and non-
Externí odkaz:
https://doaj.org/article/84426f97cc4d42e7ae2bf18cd8506826
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Kegler, A., Drewitz, L., Arndt, C., Daglar, C., Rodrigues Loureiro, L. R., Mitwasi, N., Neuber, C., González Soto, K. E., Bartsch, T., Baraban, L., Ziehr, H., Heine, M., Nieter, A., Moreira-Soto, A., Kühne, A., Drexler, J. F., Seliger, B., Laube, M., Máthé, D., Pályi, B., Hajdrik, P., Forgách, L., Kis, Z., Szigeti, K., Bergmann, R., Feldmann, A., Bachmann, M.
Publikováno v:
Frontiers in Immunology 14(2023), 1204543
The COVID-19 pandemic caused by SARS-CoV-2 led to millions of infections and deaths worldwide. As this virus evolves rapidly, there is a high need for treatment options, which can win the race against new emerging variants of concern. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::fdce3d0afa5c96d96efc48a7e94d2f77
https://www.hzdr.de/publications/Publ-37085-1
https://www.hzdr.de/publications/Publ-37085-1
Autor:
Annika Nelde, Daniel J. Kowalewski, Linus Backert, Heiko Schuster, Jan-Ole Werner, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Helmut R. Salih, Hans-Georg Rammensee, Stefan Stevanović, Juliane S. Walz
Publikováno v:
OncoImmunology, Vol 7, Iss 4 (2018)
Recent studies suggest that CLL is an immunogenic disease, which might be effectively targeted by antigen-specific T-cell-based immunotherapy. However, CLL is associated with a profound immune defect, which might represent a critical limitation for m
Externí odkaz:
https://doaj.org/article/15df9cff2f754b7fa0d8ffffe76398f3