Zobrazeno 1 - 10
of 227
pro vyhledávání: '"T cell stimulation"'
Autor:
Kathrin Balz, Magali Grange, Uta Pegel, Zain A. Karamya, Marielle Mello, Xiaoying Zhou, Thilo Berger, Konstantin Bloch, Diane Dunham, Sharon Chinthrajah, Kari Nadeau, Hervé Luche, Chrysanthi Skevaki
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Understanding antigen-specific T-cell responses, for example, following virus infections or allergen exposure, is of high relevance for the development of vaccines and therapeutics. We aimed on optimizing immunophenotyping of T cells after antigen st
Externí odkaz:
https://doaj.org/article/cd666241a2b54fa2b38d3d9aa950af30
Autor:
Daniel Snell, Tea Gunde, Stefan Warmuth, Bithi Chatterjee, Matthias Brock, Christian Hess, Maria Johansson, Alexandre Simonin, Fabio Mario Spiga, Christopher Weinert, Niels Kirk, Nicole Bassler, Lucia Campos Carrascosa, Naomi Flückiger, Robin Heiz, Sandro Wagen, Noreen Giezendanner, Alessandra Alberti, Yasemin Yaman, Dana Mahler, Dania Diem, Peter Lichtlen, David Urech
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTMesothelin (MSLN) is an attractive immuno-oncology target, but the development of MSLN-targeting therapies has been impeded by tumor shedding of soluble MSLN (sMSLN), on-target off-tumor activity, and an immunosuppressive tumor microenvironme
Externí odkaz:
https://doaj.org/article/37427098ffe74543b7338afdbca88496
Publikováno v:
Bioactive Materials, Vol 15, Iss , Pp 160-172 (2022)
In immunotherapy, ex vivo stimulation of T cells requires significant resources and effort. Here, we report artificial dendritic cell-mimicking DNA microflowers (DM) for programming T cell stimulation in situ. To mimic dendritic cells, DNA-based arti
Externí odkaz:
https://doaj.org/article/d57d76aaaadc4a6bb78eb6844a063f30
Autor:
Daniel B. Rodrigues, Helena R. Moreira, Mariana T. Cerqueira, Alexandra P. Marques, António G. Castro, Rui L. Reis, Rogério P. Pirraco
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-19 (2022)
Abstract Background T cell priming has been shown to be a powerful immunotherapeutic approach for cancer treatment in terms of efficacy and relatively weak side effects. Systems that optimize the stimulation of T cells to improve therapeutic efficacy
Externí odkaz:
https://doaj.org/article/9e240c53884d402faeacec8e70cfcb61
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Stefan Warmuth, Tea Gunde, Daniel Snell, Matthias Brock, Christopher Weinert, Alexandre Simonin, Christian Hess, Julia Tietz, Maria Johansson, Fabio Mario Spiga, Robin Heiz, Naomi Flückiger, Sandro Wagen, Julia Zeberer, Dania Diem, Dana Mahler, Belinda Wickihalder, Simone Muntwiler, Bithi Chatterjee, Benjamin Küttner, Bettina Bommer, Yasemin Yaman, Peter Lichtlen, David Urech
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Co-stimulatory 4–1BB receptors on tumor-infiltrating T cells are a compelling target for overcoming resistance to immune checkpoint inhibitors, but initial clinical studies of 4–1BB agonist mAbs were accompanied by liver toxicity. We sought to en
Externí odkaz:
https://doaj.org/article/2cef15a66dc442d1a31020e1730a9800
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3949 (2022)
European black elderberry (Sambucus nigra L.) is a popular way to treat common colds or influenza infections. Mechanistically, this might be due to a direct antiviral effect or a stimulatory effect on the immune system of the host. Here, we evaluated
Externí odkaz:
https://doaj.org/article/419e2cb42cf24446b35ad7315a70a5a7
Autor:
Tünde Fekete, Beatrix Ágics, Dóra Bencze, Krisztián Bene, Antónia Szántó, Tünde Tarr, Zoltán Veréb, Attila Bácsi, Kitti Pázmándi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
To detect replicating viruses, dendritic cells (DCs) utilize cytoplasmic retinoic acid inducible gene-(RIG) I-like receptors (RLRs), which play an essential role in the subsequent activation of antiviral immune responses. In this study, we aimed to e
Externí odkaz:
https://doaj.org/article/d1c33aeefe6c4d528205777a67b620f1
Autor:
Diallo, Madeleine Aby
Le VIH-1 reste incurable dû à sa diversité génétique et sa capacité à se cacher dans des réservoirs cellulaires. Certaines études ont révélé que le clade du VIH peut influencer l’issue de l’infection. D'autres études chez l'adulte et
Externí odkaz:
http://hdl.handle.net/1866/27605
Autor:
Stefan Warmuth, Tea Gunde, Daniel Snell, Matthias Brock, Christopher Weinert, Alexandre Simonin, Christian Hess, Julia Tietz, Maria Johansson, Fabio Mario Spiga, Robin Heiz, Naomi Flückiger, Sandro Wagen, Julia Zeberer, Dania Diem, Dana Mahler, Belinda Wickihalder, Simone Muntwiler, Bithi Chatterjee, Benjamin Küttner, Bettina Bommer, Yasemin Yaman, Peter Lichtlen, David Urech
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Co-stimulatory 4–1BB receptors on tumor-infiltrating T cells are a compelling target for overcoming resistance to immune checkpoint inhibitors, but initial clinical studies of 4–1BB agonist mAbs were accompanied by liver toxicity. We sought to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c65a392b42386048d75da1b31b47ae5
https://pubmed.ncbi.nlm.nih.gov/35844969
https://pubmed.ncbi.nlm.nih.gov/35844969