Zobrazeno 1 - 10
of 4 685
pro vyhledávání: '"T cell response"'
Autor:
Yogita Rajput, Arvind Neral, Nikita Sherwani, Vijaylakshmi Jain, Malti Sahu, Fulsay Paikra, Aarti Kushwaha, Aparna Sahu, Heeramani Lodhi, Omprakash Sundrani, Ravindra Kumar Panda, Vinit Jain, Masood A. Shammas, Jagannath Pal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Unpredictable fatal outcome of COVID-19 is attributed to dysregulated inflammation. Impaired early adaptive immune response leads to late-stage inflammatory outcome. The purpose of this study was to develop biomarkers for early detection of
Externí odkaz:
https://doaj.org/article/9756de8050f84618b29c49962e691046
Autor:
Franziska Fischer, Johannes Mücke, Louisa Werny, Katrin Gerrer, Lorenz Mihatsch, Stefanie Zehetmaier, Isa Riedel, Jonas Geisperger, Maren Bodenhausen, Lina Schulte-Hillen, Dieter Hoffmann, Ulrike Protzer, Josef Mautner, Uta Behrends, Tanja Bauer, Nina Körber
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Infection with the Epstein-Barr virus (EBV) elicits a complex T-cell response against a broad range of viral proteins. Hence, identifying potential differences in the cellular immune response of patients with different EBV-associa
Externí odkaz:
https://doaj.org/article/4e4abcc0fc7141f2a905e4cbc62eafc1
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 1381-1393 (2024)
Bennan Zhao,1,* Qingxiao Liu,2,* Qing Du,3 Jun Kang,1 Rong Tang,4 Yalan Tu,5 Dafeng Liu1 1The First Ward of Internal Medicine, Public Health Clinical Center of Chengdu, Chengdu, People’s Republic of China; 2Department of Neurology, Hospital
Externí odkaz:
https://doaj.org/article/0ea61d6ddba34bbcb7c5cfb51b5562ee
Autor:
Jun-Hong Xing, Tian-Ming Niu, Bo-Shi Zou, Gui-Lian Yang, Chun-Wei Shi, Qing-Song Yan, Ming-Jie Sun, Tong Yu, Shu-Min Zhang, Xi-Ze Feng, Shu-Hui Fan, Hai-Bin Huang, Jun-Hong Wang, Ming-Han Li, Yan-Long Jiang, Jian-Zhong Wang, Xin Cao, Nan Wang, Yan Zeng, Jing-Tao Hu, Di Zhang, Wu-Sheng Sun, Wen-Tao Yang, Chun-Feng Wang
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-25 (2024)
Abstract Background The gut microbiota is a critical factor in the regulation of host health, but the relationship between the differential resistance of hosts to pathogens and the interaction of gut microbes is not yet clear. Herein, we investigated
Externí odkaz:
https://doaj.org/article/fd240ba8806c4d35acba3adcd3a20e20
Autor:
Anuradha S. Tripathy, Dharmendra Singh, Diptee Trimbake, Sukeshani Salwe, Srikanth Tripathy, Arjun Kakrani, Priyanka Jali, Hanmant Chavan, Pragya Yadav, Rima Sahay, Prakash Sarje, Prasad Babar, Anita Shete, Ashok Nandapurkar, Milind Kulkarni
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Several COVID-19 vaccines were developed using different approaches to prevent both symptomatic COVID-19 cases and fatalities. The adults were vaccinated with two doses of AZD1222/Covishield (n = 77) [manufactured by Serum Institute of India Pvt Ltd]
Externí odkaz:
https://doaj.org/article/f92581fa1d4842b89feaee2c5d3d4f27
Autor:
Xinyu Zhang, Yanhong Chen, Shuhui Wang, Ling Zhong, Zheng Xiang, Xiao Zhang, Shanshan Zhang, Xiang Zhou, Wanlin Zhang, Yan Zhou, Qiuting Zhang, Jingtong Liang, Yanran Luo, Yufei Wang, Ling Chen, Xiaoping Ye, Qisheng Feng, Mu-Sheng Zeng, Ying Liu, Yi-Xin Zeng, Yiming Shao, Miao Xu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Epstein–Barr virus (EBV) infection has been related to multiple epithelial cancers and lymphomas. Current efforts in developing a prophylactic EBV vaccine have focused on inducing neutralizing antibodies. However, given the lifelong and persistent
Externí odkaz:
https://doaj.org/article/f7d0204b93db4bb1a89729dce21b35bb
Autor:
Lulu Huang, Shun Zhang, Tongyi Zhao, Ting Cai, Lingling Bu, Zhenhua Di, Yujie Zhang, Chen Yang, Yong Yang, Ang Lin
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
mRNA platform holds promise for next-generation Varicella-zoster Virus (VZV) vaccine development due to its high potency at inducing strong T-cell response. Built upon the design of our 1st-generation VZV mRNA vaccine that encodes for full-length gE
Externí odkaz:
https://doaj.org/article/4ade3a6adf0242be84fbec5123300e61
Autor:
Jiapei Yu, Congcong Shang, Xiaoyan Deng, Ju Jia, Xiao Shang, Zeyi Wang, Ying Zheng, Rongling Zhang, Yeming Wang, Hui Zhang, Hongyu Liu, William J. Liu, Hui Li, Bin Cao
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Throughout history, the influenza A virus has caused numerous devastating global pandemics. Macrophages, as pivotal innate immune cells, exhibit a wide range of immune functions characterized by distinct polarization states, reflecting their intricat
Externí odkaz:
https://doaj.org/article/6ea0c2a1096a45f7870373cf614d1ed0
Autor:
Changxing Gao, Mei Liu, Yue Xin, Yong Zeng, Hui Yang, Xinyu Fan, Cheng Zhao, Bo Zhang, Lingzhi Zhang, Jing J. Li, Ming Zhao, Zijun Wang, Qianjin Lu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract Background The meticulous selection of appropriate vaccine adjuvants is crucial for optimizing immune responses. Traditionally, pemphigus vulgaris (PV), an autoimmune disorder, has been modelled using complete Freund's adjuvant (CFA). In thi
Externí odkaz:
https://doaj.org/article/606d8f8fe24f43149453c44ee5b9d6b9
Autor:
Tim R. Mosmann, Jonathan A. Rebhahn, Stephen C. De Rosa, Michael C. Keefer, M. Juliana McElrath, Nadine G. Rouphael, Giuseppe Pantaleo, Peter B. Gilbert, Lawrence Corey, James J. Kobie, Juilee Thakar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe HVTN 105 vaccine clinical trial tested four combinations of two immunogens - the DNA vaccine DNA-HIV-PT123, and the protein vaccine AIDSVAX B/E. All combinations induced substantial antibody and CD4+ T cell responses in many participa
Externí odkaz:
https://doaj.org/article/52dd5afd41534ef9921ac84b943b0929