Zobrazeno 1 - 10
of 467
pro vyhledávání: '"T cell mediated immunity"'
Autor:
Oana Diana Preda, Sorina Bădeliță, Iulia Ursuleac, Ruxandra Maria Irimia, Sonia Balanica, Monica Cojocaru, Cristina Cotruta, Camelia Dobrea, Daniel Coriu
Publikováno v:
Hematology Reports, Vol 16, Iss 2, Pp 299-307 (2024)
Background: Brentuximab Vedotin (BV) has revolutionized the treatment landscape for Hodgkin’s lymphoma, yet its effects on pre-existing autoimmune disorders remain elusive. Methods: Here, we present four cases of patients with concurrent autoimmune
Externí odkaz:
https://doaj.org/article/01f1b47944764b9c933513ad5b91d2f4
Autor:
Bhawna Sharma, Elena Bekerman, Hoa Truong, Johnny Lee, Maria Gamez-Guerrero, Archana Boopathy, Rohit Mital, Katell Bidet Huang, Sarah Ahmadi-Erber, Raphaela Wimmer, Sophie Schulha, Henning Lauterbach, Klaus Orlinger, Silpa Suthram, Mark G. Lewis, Wade Blair, Tariro Makadzange, Romas Geleziunas, Jeffrey P. Murry, Sarah Schmidt
Publikováno v:
Vaccines, Vol 12, Iss 7, p 735 (2024)
Arenavirus-based vectors are being investigated as therapeutic vaccine candidates with the potential to elicit robust CD8 T-cell responses. We compared the immunogenicity of replicating (artPICV and artLCMV) and non-replicating (rPICV and rLCMV) aren
Externí odkaz:
https://doaj.org/article/12cd484f588c476caa2e1468f51b5006
Autor:
Jinsong Zhang, Jianghua Yang, Qianlin Li, Ruihao Peng, Shoudong Fan, Huaimin Yi, Yuying Lu, Yuanli Peng, Haozhen Yan, Lidan Sun, Jiahai Lu, Zeliang Chen
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Antigen delivery based on non‐virus‐like particle self‐associating protein nanoscffolds, such as Aquifex aeolicus lumazine synthase (AaLS), is limited due to the immunotoxicity and/or premature clearance of antigen‐scaffold complex r
Externí odkaz:
https://doaj.org/article/09b1a2b7f17d4b049923de434e79e28d
Autor:
Tim K. Tsang, Kwok-Tai Lam, Yinping Liu, Vicky J. Fang, Xiaofeng Mu, Nancy H. L. Leung, J. S. Malik Peiris, Gabriel M. Leung, Benjamin J. Cowling, Wenwei Tu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The protective effect of T cell-mediated immunity against influenza virus infections in natural settings remains unclear, especially in seasonal epidemics. Methods To explore the potential of such protection, we analyzed the blood
Externí odkaz:
https://doaj.org/article/ce7914eb109b444984597152877d9f03
Autor:
Antti Hurme, Pinja Jalkanen, Minna Marttila-Vaara, Jemna Heroum, Heidi Jokinen, Saimi Vara, Oona Liedes, Johanna Lempainen, Merit Melin, Ilkka Julkunen, Leena Kainulainen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Primary antibody deficiencies, such as common variable immunodeficiency (CVID), are heterogenous disease entities consisting of primary hypogammaglobulinemia and impaired antibody responses to vaccination and natural infection. CVID is the most commo
Externí odkaz:
https://doaj.org/article/cf14b535be11405fa6025bf0759a239d
Autor:
Yashan Bu, Kendrick Co Shih, Ho Lam Wong, Sum Sum Kwok, Amy Cheuk-Yin Lo, Joseph Yau-Kei Chan, Alex Lap-Ki Ng, Tommy Chung-Yan Chan, Vishal Jhanji, Louis Tong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeWe aim to investigate the effect of sustained hyperglycemia on corneal epithelial wound healing, ocular surface and systemic immune response, and microbiome indices in diabetic mice compared to controls after alkaline chemical injury of the ey
Externí odkaz:
https://doaj.org/article/b991c22f3ee84e6db208911ff01e30fe
Akademický článek
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Autor:
Lipin Liu, Bijun Sun, Wenjing Ying, Danru Liu, Ying Wang, Jinqiao Sun, Wenjie Wang, Mi Yang, Xiaoying Hui, Qinhua Zhou, Jia Hou, Xiaochuan Wang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Talaromyces marneffei (T. marneffei) is an opportunistic pathogen. Patients with inborn errors of immunity (IEI) have been increasingly diagnosed with T. marneffei in recent years. The disseminated infection of T. marneffei can be life-threatening wi
Externí odkaz:
https://doaj.org/article/2c3145da55874e29b22c98946baa0fa6
Long-Lasting T Cell Responses in BNT162b2 COVID-19 mRNA Vaccinees and COVID-19 Convalescent Patients
Autor:
Antti Hurme, Pinja Jalkanen, Jemna Heroum, Oona Liedes, Saimi Vara, Merit Melin, Johanna Teräsjärvi, Qiushui He, Sakari Pöysti, Arno Hänninen, Jarmo Oksi, Tytti Vuorinen, Anu Kantele, Paula A. Tähtinen, Lauri Ivaska, Laura Kakkola, Johanna Lempainen, Ilkka Julkunen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The emergence of novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made it more difficult to prevent the virus from spreading despite available vaccines. Reports of breakthrough infections and decreased capacity o
Externí odkaz:
https://doaj.org/article/e8a1c8a39f4545bf9a1055f78f72e7cf
Publikováno v:
Vaccines, Vol 11, Iss 3, p 548 (2023)
The adaptive (T-cell-mediated) immune response is a key player in determining the clinical outcome, in addition to neutralizing antibodies, after SARS-CoV-2 infection, as well as supporting the efficacy of vaccines. T cells recognize viral-derived pe
Externí odkaz:
https://doaj.org/article/11ed2ce986524cd789396e2205fe6f01