Zobrazeno 1 - 10
of 706
pro vyhledávání: '"T cell homeostasis"'
Autor:
Dohnke, Sebastian, Moehser, Stephanie, Surnov, Alexey, Kurth, Thomas, Jessberger, Rolf, Kretschmer, Karsten, Garbe, Annette I.
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91929
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
Autor:
Nannan Sun, Mengmeng Zhang, Jingjing Kong, Jin Li, Yong Dong, Xiaoqian Wang, Liyan Fu, Yiwei Zhou, Yaoyao Chen, Yingmei Li, Xianlei Sun, Rongqun Guo
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35775- (2024)
Aplastic anemia (AA) is an autoimmune hematopoietic disease mediated by autoreactive T cells leading to bone marrow failure. However, the precise role of autoreactive T cells in the development of AA is not fully understood, hindering the advancement
Externí odkaz:
https://doaj.org/article/cc3cc2523b4c4587be54684cb3e6c172
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn vivo T cell migration has been of interest to scientists for the past 60 years. T cell kinetics are important in the understanding of the immune response to infectious agents. More recently, adoptive T cell therapies have proven to be
Externí odkaz:
https://doaj.org/article/104efaa5aded44e295627f1eaa31bc94
Autor:
Jia Song, Xin Zhang, Yue Yin, Mengfan Guo, Xuyang Zhao, Likun Wang, Caixia Ren, Yuxin Yin, Xuehui Zhang, Xuliang Deng, Dan Lu
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract The peripheral T cell pool is maintained at dynamic homeostasis through fine‐tuning of thymic output and self‐renewal of naïve T cells. Lymphopenia or reduced lymphocyte number is implicated in autoimmune diseases, yet little is known a
Externí odkaz:
https://doaj.org/article/2189e4ea77284ef3a45bba4a60833168
Akademický článek
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Akademický článek
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Autor:
Gilbert Aaron Lee, Nan-Shih Liao
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 3, Pp 514-517 (2021)
The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells
Externí odkaz:
https://doaj.org/article/d42f0f020327408aaa4db02fe7e73fea
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T (Treg) cells are garnering increased attention in research related to autoimmune diseases, including rheumatoid arthritis (RA). They play an essential role in the maintenance of immune homeostasis by restricting effector T cell activity.
Externí odkaz:
https://doaj.org/article/89634c9a00084e9c8784d5f2a61ccf07
Autor:
Bin Hu, Rohit R. Jadhav, Claire E. Gustafson, Sabine Le Saux, Zhongde Ye, Xuanying Li, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1ffebb6d2fb24fafa2db95ebc9619d17
Autor:
Sebastian Dohnke, Stephanie Moehser, Alexey Surnov, Thomas Kurth, Rolf Jessberger, Karsten Kretschmer, Annette I. Garbe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://doaj.org/article/a04c09087b1344e5a827e4d3f0519357